Between the 2000 and 2010 seasons, Adam Dunn had the most strikeouts, with 1,632 strikeouts.

Interpreted as:

most strikeouts by a player between 2000 to 2010

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Adam Dunn A. Dunn	1,632	1,448	4,975	865	1,246	266	10	354	880	990	71	59	21	6,065	2,594	630	2	27	107	75	.250	.381	.521	.902	1019	282.8	.384	131	239.2
2	Jim Thome J. Thome	1,513	1,476	4,905	925	1,333	247	10	393	1,045	1,033	39	3	9	6,021	2,779	650	0	44	116	89	.272	.399	.567	.966	1128	387	.406	146	352.2
3	Pat Burrell P. Burrell	1,497	1,548	5,320	750	1,351	290	15	285	955	899	29	7	3	6,301	2,526	590	0	53	53	117	.254	.362	.475	.837	942	170.8	.361	117	139
4	Mike Cameron M. Cameron	1,473	1,435	5,236	823	1,324	303	42	225	775	663	70	208	57	6,034	2,386	570	18	47	16	90	.253	.342	.456	.798	827	84.1	.346	112	90.9
5	Bobby Abreu B. Abreu	1,353	1,728	6,373	1,149	1,867	449	38	236	1,071	1,125	28	319	100	7,599	3,100	723	2	71	85	127	.293	.398	.486	.884	1271	341.2	.382	132	311
6	Alex Rodriguez A. Rodriguez	1,341	1,661	6,254	1,264	1,881	314	18	465	1,368	909	128	183	40	7,363	3,626	797	0	72	83	156	.301	.396	.580	.976	1414	512.2	.412	152	476.8
7	Alfonso Soriano A. Soriano	1,307	1,460	5,899	926	1,633	374	27	313	838	383	68	262	71	6,400	3,000	714	9	41	55	76	.277	.326	.509	.835	916	136.6	.354	112	99.2
8	Derrek Lee D. Lee	1,298	1,596	5,801	934	1,678	374	26	289	921	768	54	95	44	6,674	2,971	689	2	49	68	169	.289	.375	.512	.887	1100	285.2	.380	129	246.3
9	Andruw Jones A. Jones	1,247	1,520	5,497	893	1,404	275	21	327	965	655	72	78	32	6,283	2,702	623	0	59	47	153	.255	.339	.492	.831	906	132.2	.354	113	101.2
10	Troy Glaus T. Glaus	1,183	1,335	4,694	785	1,207	255	10	290	848	768	40	50	28	5,542	2,352	555	0	40	39	126	.257	.364	.501	.865	876	195.6	.371	125	176
11	Jim Edmonds J. Edmonds	1,171	1,302	4,214	787	1,181	276	13	272	791	724	34	41	26	5,029	2,299	561	7	50	69	73	.280	.386	.546	.932	892	272.3	.394	139	255
12	Jorge Posada J. Posada	1,155	1,422	4,809	730	1,346	311	8	226	876	766	66	18	16	5,678	2,351	545	0	37	63	143	.280	.384	.489	.872	924	226.6	.377	129	212.4
13	Richie Sexson R. Sexson	1,152	1,179	4,264	647	1,107	229	9	264	792	548	45	10	9	4,885	2,146	502	0	28	31	120	.260	.348	.503	.851	743	139.3	.364	120	126.1
14	David Ortiz D. Ortiz	1,149	1,485	5,343	917	1,505	393	15	339	1,118	831	26	9	6	6,259	2,945	747	2	57	101	118	.282	.377	.551	.929	1092	326.5	.391	136	282.6
15	Manny Ramirez M. Ramirez	1,146	1,448	5,196	971	1,641	344	11	357	1,148	874	75	11	10	6,194	3,078	712	0	49	178	154	.316	.418	.592	1.011	1243	482.7	.422	157	449
16	Carlos Pena C. Pena	1,131	1,073	3,620	559	871	171	20	230	650	582	54	23	14	4,295	1,772	421	4	35	37	49	.241	.351	.490	.841	640	121.2	.361	123	123.4
17	Carlos Delgado C. Delgado	1,121	1,368	4,951	863	1,416	326	12	324	1,045	796	126	9	3	5,938	2,738	662	0	65	151	108	.286	.394	.553	.947	1069	335.2	.397	141	309.5
18	Lance Berkman L. Berkman	1,115	1,595	5,573	1,007	1,653	380	26	323	1,084	1,045	61	77	41	6,729	3,054	729	1	49	137	128	.297	.410	.548	.958	1258	434.4	.406	146	392.3
19	Brandon Inge B. Inge	1,109	1,297	4,337	496	1,028	201	36	136	564	393	64	44	38	4,873	1,709	373	38	41	15	83	.237	.307	.394	.701	507	-83.7	.307	84	-95.9
20	Derek Jeter D. Jeter	1,099	1,657	6,785	1,199	2,119	346	30	171	794	675	116	237	52	7,662	3,038	547	59	27	30	183	.312	.383	.448	.830	1174	236.7	.365	122	215.4
21	Torii Hunter T. Hunter	1,098	1,509	5,666	855	1,565	340	27	249	932	449	59	162	74	6,213	2,706	616	1	38	47	170	.276	.334	.478	.811	856	97.4	.348	111	81.9
22	Russell Branyan R. Branyan	1,056	979	2,765	390	649	134	8	188	447	382	29	14	4	3,206	1,363	330	4	26	30	29	.235	.331	.493	.824	451	60.9	.351	113	53.2
23	Geoff Jenkins G. Jenkins	1,038	1,130	3,991	585	1,093	248	18	191	623	363	87	26	10	4,476	1,950	457	0	35	66	96	.274	.345	.489	.833	643	88.7	.354	111	63.6
24	Ryan Howard R. Howard	1,035	875	3,237	552	902	159	16	253	748	465	33	11	4	3,765	1,852	428	0	30	116	64	.279	.372	.572	.944	656	200.4	.392	137	174.7
25	Jermaine Dye J. Dye	1,025	1,372	5,110	806	1,406	284	16	274	871	503	57	39	16	5,722	2,544	574	1	51	34	142	.275	.344	.498	.841	848	142.6	.359	114	106.2