Kerry Wood has struck out the most hitters by a rookie in a game, with 20 strikeouts versus the Astros on May 6, 1998.
Interpreted as:
most strikeouts by a rookie pitcher in a regular-season game| NAME | SO | DATE | TM | OPP | DEC | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | K. Wood | 20 | 5/6/1998 |  CHC | vs |  HOU | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 29 | 0 |
| 2 | | B. Gullickson | 18 | 9/10/1980 |  MON | vs | CHC | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 4 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 33 | 1 |
| 3 | | J. Coombs | 18 | 9/1/1906 |  PHA | @ |  BSA | W | 1 | 1 | 0 | 0 | 24.0 | 15 | 1 | 0 | 6 | 1 | 0 | 89 | 0 | |||
| 4 | | B. Feller | 17 | 9/13/1936 |  CLE | vs | PHA | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 2 | 2 | 2 | 0 | 9 | 1 | 0 | 39 | 1 | |
| 5 | | J. Pfiester | 17 | 5/30/1906 |  CHC | vs |  SLN | L | 1 | 1 | 0 | 0 | 15.0 | 12 | 4 | 0 | 2 | 0 | 0 | 57 | 0 | |||
| 6 |  | S. Strider | 16 | 9/1/2022 |  ATL | vs |  COL | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27 | 0 |
| 7 | | J. Gray | 16 | 9/17/2016 | COL | vs |  SDP | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 31 | 0 |
| 8 | | K. Wood | 16 | 8/26/1998 | CHC | @ |  CIN | W | 1 | 1.13 | 0 | 0 | 0 | 8.0 | 3 | 1 | 2 | 1 | 3 | 0 | 0 | 0 | 30 | 0 |
| 9 | | H. Nomo | 16 | 6/14/1995 |  LAD | @ |  PIT | W | 1 | 2.25 | 0 | 0 | 0 | 8.0 | 6 | 2 | 3 | 0 | 2 | 1 | 0 | 0 | 33 | 1 |
| 10 | | D. Gooden | 16 | 9/17/1984 |  NYM | @ |  PHI | L | 1 | 1.13 | 1 | 0 | 0 | 8.0 | 7 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 30 | 1 |
| 11 | | D. Gooden | 16 | 9/12/1984 | NYM | vs | PIT | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 32 | 0 |
| 12 | | H. Score | 16 | 5/1/1955 | CLE | vs |  BOS | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 4 | 1 | 1 | 0 | 4 | 0 | 0 | 0 | 34 | 0 |
| 13 | | J. Harshman | 16 | 7/25/1954 |  CWS | @ | BOS | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 5 | 2 | 2 | 0 | 5 | 0 | 0 | 1 | 36 | 0 |
| 14 |  | R. Clemens | 15 | 8/21/1984 |  BOS | vs |  KCR | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 7 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 33 | 0 |
| 15 | | J. Bibby | 15 | 8/30/1973 |  TEX | vs |  MIN | L | 1 | 4.22 | 0 | 0 | 0 | 10.2 | 7 | 5 | 5 | 0 | 6 | 0 | 0 | 0 | 44 | 0 |
| 16 | | B. Hooton | 15 | 9/15/1971 |  CHC | @ | NYM | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 3 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 32 | 0 |
| 17 | | J.R. Richard | 15 | 9/5/1971 |  HOU | @ |  SFG | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 7 | 2 | 3 | 0 | 3 | 0 | 0 | 0 | 38 | 0 |
| 18 | | M. Wegener | 15 | 9/10/1969 | MON | @ | NYM | 1 | 0.00 | 0 | 0 | 0 | 11.0 | 5 | 0 | 2 | 0 | 7 | 0 | 0 | 1 | 45 | 0 | |
| 19 | | D. Wilson | 15 | 6/18/1967 | HOU | vs | ATL | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 30 | 0 |
| 20 | | G. Nolan | 15 | 6/7/1967 | CIN | vs | SFG | 1 | 3.52 | 0 | 0 | 0 | 7.2 | 8 | 3 | 3 | 1 | 0 | 0 | 0 | 0 | 31 | 0 | |
| 21 | | D. Drott | 15 | 5/26/1957 | CHC | vs |  MIL | W | 1 | 4.00 | 1 | 0 | 0 | 9.0 | 7 | 4 | 5 | 2 | 1 | 0 | 0 | 0 | 37 | 0 |
| 22 | | K. Spooner | 15 | 9/22/1954 |  BKN | vs |  NYG | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 34 | 0 |
| 23 | | B. Feller | 15 | 8/23/1936 | CLE | vs |  SLA | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 6 | 1 | 1 | 0 | 4 | 0 | 0 | 37 | 1 | |
| 24 | | F. Glade | 15 | 7/15/1904 | SLA | @ |  WSH | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 7 | 1 | 2 | 0 | 0 | 2 | 0 | 39 | 0 | |
| 25 | | T. Hughes | 15 | 7/31/1901 |  CHO | @ | CIN | L | 1 | 3.29 | 1 | 0 | 0 | 13.2 | 13 | 5 | 5 | 0 | 6 | 0 | 0 | 58 | 1 | |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
Brewers 
Cardinals 
Phillies 
Padres 
Blue Jays 
Yankees 
Guardians 
Tigers 
Mariners 
Astros 
WSH 
TBR 
BAL 
