Since 2000, Joey Votto has the most strikeouts versus the Cardinals, with 170 strikeouts.

Interpreted as:

most strikeouts by a player vs cardinals since 2000

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Joey Votto J. Votto	170	224	774	124	231	50	3	36	112	156	8	6	1	944	395	89	0	6	13	16	.298	.418	.510	.929
2	Andrew McCutchen A. McCutchen	169	208	790	119	210	44	3	19	86	91	4	12	7	893	317	66	0	8	9	15	.266	.342	.401	.743
3	Ryan Braun R. Braun	158	196	745	85	205	41	5	30	97	41	6	6	3	796	346	76	0	4	5	29	.275	.317	.464	.781
4	Jay Bruce J. Bruce	135	145	548	64	127	20	5	23	75	42	1	2	3	598	226	48	1	6	4	7	.232	.285	.412	.697
5	Adam Dunn A. Dunn	118	130	426	73	99	23	0	32	78	88	4	4	2	523	218	55	0	5	4	8	.232	.365	.512	.877
6	Eugenio Suárez E. Suárez	116	123	443	61	113	25	1	26	80	42	5	2	1	493	218	52	1	2	2	8	.255	.325	.492	.817
7	Lance Berkman L. Berkman	112	153	548	98	172	37	2	39	118	92	7	4	4	652	330	78	0	5	12	12	.314	.416	.602	1.018
8	Ian Happ I. Happ	110	123	381	62	97	24	2	27	67	63	4	4	1	451	206	53	1	2	2	10	.255	.364	.541	.905
9	Kyle Schwarber K. Schwarber	110	96	327	37	58	11	0	14	37	57	2	1	0	387	111	25	0	1	6	4	.177	.302	.339	.642
10	Christian Yelich C. Yelich	108	118	420	78	115	18	2	22	69	67	2	6	1	490	203	42	0	1	5	8	.274	.376	.483	.859
11	Javier Báez J. Báez	107	112	356	46	84	13	2	13	42	20	6	4	3	384	140	28	2	0	3	9	.236	.288	.393	.681
12	Brandon Phillips B. Phillips	107	175	673	94	184	42	5	17	87	40	7	12	8	735	287	64	8	7	6	20	.273	.318	.426	.744
13	Geoff Jenkins G. Jenkins	107	112	397	61	118	33	2	16	55	41	11	4	1	453	203	51	0	4	8	8	.297	.375	.511	.887
14	Kris Bryant K. Bryant	104	100	372	52	90	19	3	10	49	38	10	0	1	423	145	32	0	3	2	6	.242	.326	.390	.716
15	Starling Marte S. Marte	103	129	501	65	143	20	9	8	45	26	18	16	3	550	205	37	3	2	1	16	.285	.342	.409	.751
16	Hunter Pence H. Pence	100	111	419	54	125	17	4	14	58	22	1	8	4	443	192	35	0	1	0	10	.298	.334	.458	.792
17	Derrek Lee D. Lee	100	128	472	78	150	39	0	25	66	64	2	5	1	542	264	64	1	3	8	19	.318	.399	.559	.959
18	Rickie Weeks Jr. R. Weeks Jr.	98	110	353	55	78	17	2	16	39	41	11	5	2	407	147	35	0	2	1	5	.221	.319	.416	.736
19	Alfonso Soriano A. Soriano	97	98	379	39	90	23	2	12	49	26	3	5	2	411	153	37	0	3	1	10	.237	.290	.404	.693
20	Aramis Ramirez A. Ramirez	94	211	793	106	247	49	3	38	146	63	10	1	1	872	416	90	0	6	7	20	.311	.367	.525	.892
21	Bryan Reynolds B. Reynolds	92	100	374	46	89	22	2	10	44	28	7	4	0	412	145	34	0	3	2	10	.238	.301	.388	.689
22	Starlin Castro S. Castro	88	121	480	52	137	26	4	10	58	14	5	3	3	504	201	40	1	4	4	19	.285	.310	.419	.729
23	Willson Contreras W. Contreras	87	95	297	42	74	10	1	15	47	46	10	2	2	354	131	26	1	0	3	8	.249	.368	.441	.809
24	Pedro Alvarez P. Alvarez	86	85	299	35	76	16	0	18	58	35	1	2	1	336	146	34	0	1	8	8	.254	.333	.488	.822
25	Jason Bay J. Bay	83	82	284	39	72	11	1	14	45	34	6	2	2	331	127	26	1	6	2	6	.254	.339	.447	.787

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StatMuse has game-level data for strikeouts going back to the 1916 season.

Some of the information used here was obtained free of charge from Retrosheet.

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Thu 3/26	BOS	@	CIN	4:10 PM
Sat 3/28	BOS	@	CIN	4:10 PM
Sun 3/29	BOS	@	CIN	1:40 PM
Mon 3/30	PIT	@	CIN	6:40 PM
Tue 3/31	PIT	@	CIN	6:40 PM

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Phillies - y	96	66	.593
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Marlins	79	83	.488	17.0
Braves	76	86	.469	20.0
Nationals	66	96	.407	30.0
NL Central	W	L	PCT	GB
Brewers - y	97	65	.599
Cubs - w	92	70	.568	5.0
Reds - w	83	79	.512	14.0
Cardinals	78	84	.481	19.0
Pirates	71	91	.438	26.0
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Dodgers - y	93	69	.574
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Diamondbacks	80	82	.494	13.0
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Yankees - w	94	68	.580
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Royals	82	80	.506	6.0
Twins	70	92	.432	18.0
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Astros	87	75	.537	3.0
Rangers	81	81	.500	9.0
Athletics	76	86	.469	14.0
Angels	72	90	.444	18.0