Between the 2012 and 2015 seasons, the Baltimore Orioles had the most wins by an AL team, with 355 wins.

Interpreted as:

most team regular-season wins in al from 2012 to 2015

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Orioles	355	293	.548	648	22,261	2,875	5,639	1,078	66	854	2,763	1,715	199	5,056	225	103	24,438	9,411	1,998	120	143	112	496	.253	.311	.423	.733
2	Yankees	351	297	.542	648	22,037	2,851	5,529	1,046	82	748	2,716	2,037	238	4,750	383	109	24,618	8,983	1,876	120	186	103	473	.251	.319	.408	.726
3	Angels	350	298	.540	648	22,193	2,934	5,789	1,090	113	682	2,778	1,899	213	4,750	349	140	24,651	9,151	1,885	147	199	145	516	.261	.322	.412	.735
4	Athletics	346	302	.534	648	22,193	2,903	5,477	1,098	136	673	2,748	2,184	179	4,788	357	109	24,801	8,866	1,907	81	164	113	447	.247	.317	.399	.717
5	Tigers	345	302	.533	647	22,446	2,968	6,164	1,185	137	645	2,856	1,940	185	4,579	283	135	24,868	9,558	1,967	115	182	173	591	.275	.335	.426	.761
6	Royals	342	306	.528	648	22,305	2,699	5,888	1,135	142	477	2,556	1,589	214	4,038	542	140	24,415	8,738	1,754	130	177	123	525	.264	.317	.392	.708
7	Rangers	339	310	.522	649	22,146	2,926	5,810	1,104	115	659	2,775	1,860	255	4,565	446	188	24,620	9,121	1,878	165	194	139	492	.262	.324	.412	.736
8	Rays	339	310	.522	649	21,937	2,653	5,458	1,087	109	624	2,533	2,123	244	4,928	357	154	24,621	8,635	1,820	120	197	110	529	.249	.319	.394	.713
9	Indians	326	321	.504	647	22,004	2,750	5,582	1,143	99	590	2,630	2,154	191	4,716	417	135	24,689	8,693	1,832	146	194	105	507	.254	.323	.395	.718
10	Blue Jays	323	325	.498	648	22,082	3,042	5,659	1,110	87	792	2,888	2,055	188	4,676	401	126	24,643	9,319	1,989	133	185	87	510	.256	.322	.422	.744
11	Red Sox	315	333	.486	648	22,446	2,969	5,875	1,278	98	627	2,821	2,022	231	4,990	354	102	25,006	9,230	2,003	108	199	142	507	.262	.326	.411	.738
12	Mariners	309	339	.477	648	22,046	2,533	5,310	999	98	671	2,405	1,869	157	5,180	318	145	24,335	8,518	1,768	131	132	106	452	.241	.303	.386	.689
13	White Sox	297	351	.458	648	22,157	2,628	5,575	1,004	107	650	2,520	1,693	224	5,003	367	163	24,332	8,743	1,761	99	159	102	488	.252	.309	.395	.704
14	Twins	285	363	.440	648	22,160	2,726	5,555	1,148	116	566	2,592	2,021	198	5,092	356	144	24,669	8,633	1,830	117	173	108	482	.251	.317	.390	.706
15	Astros	207	279	.426	486	16,363	1,968	3,987	784	61	541	1,853	1,407	163	4,369	353	146	18,146	6,516	1,386	96	117	66	334	.244	.308	.398	.706