Since 2022, the Los Angeles Dodgers have the most wins by a team, with 346 wins.

Interpreted as:

most regular-season wins by a MLB team since 2022

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	346	201	.633	547	18,664	2,947	4,822	1,025	86	794	2,843	2,086	225	4,574	379	78	21,190	8,401	1,905	21	194	97	329	.258	.337	.450	.787
2	Braves	321	224	.589	545	18,589	2,679	4,761	946	55	826	2,572	1,693	208	4,749	323	89	20,637	8,295	1,827	18	129	48	386	.256	.323	.446	.769
3	Astros	317	228	.582	545	18,497	2,546	4,732	909	57	687	2,446	1,699	227	4,053	313	91	20,609	7,816	1,653	43	143	69	423	.256	.324	.423	.746
4	Yankees	312	233	.572	545	18,195	2,617	4,383	796	48	807	2,505	2,092	195	4,662	332	103	20,678	7,696	1,651	38	158	96	414	.241	.323	.423	.746
5	Phillies	309	237	.566	546	18,625	2,616	4,761	923	91	689	2,514	1,753	205	4,687	450	95	20,761	7,933	1,703	37	141	64	369	.256	.324	.426	.750
6	Brewers	305	244	.556	549	18,389	2,518	4,425	846	71	619	2,405	1,981	209	4,847	524	119	20,751	7,270	1,536	48	124	67	386	.241	.320	.395	.715
7	Mets	303	244	.554	547	18,385	2,526	4,551	876	76	662	2,422	1,768	349	4,399	332	67	20,694	7,565	1,614	52	140	60	386	.248	.323	.411	.735
8	Padres	299	246	.549	545	18,353	2,463	4,576	893	57	601	2,353	1,869	193	4,124	349	94	20,636	7,386	1,551	82	139	64	400	.249	.323	.402	.725
9	Orioles	298	247	.547	545	18,458	2,494	4,541	932	94	652	2,391	1,641	218	4,636	350	93	20,511	7,617	1,678	41	153	42	326	.246	.313	.413	.725
10	Rays	296	250	.542	546	18,315	2,391	4,460	916	67	578	2,274	1,689	246	4,802	517	148	20,392	7,244	1,561	24	118	36	329	.244	.314	.396	.709
11	Mariners	295	250	.541	545	18,210	2,388	4,238	810	47	672	2,288	1,934	347	5,153	395	103	20,654	7,158	1,529	36	127	48	356	.233	.316	.393	.709
12	Guardians	292	252	.537	544	18,304	2,305	4,502	894	84	497	2,178	1,577	246	3,930	462	123	20,349	7,055	1,475	60	162	115	368	.246	.312	.385	.697
13	Blue Jays	286	260	.524	546	18,541	2,443	4,702	981	59	604	2,342	1,771	223	4,198	273	94	20,703	7,613	1,644	39	129	56	436	.254	.324	.411	.735
14	Cardinals	280	266	.513	546	18,551	2,443	4,652	923	58	625	2,340	1,782	233	4,335	323	95	20,754	7,566	1,606	41	147	47	370	.251	.322	.408	.730
15	Twins	280	266	.513	546	18,474	2,469	4,533	939	72	653	2,357	1,755	296	4,808	221	70	20,697	7,575	1,664	33	139	43	404	.245	.319	.410	.729
16	Cubs	278	268	.509	546	18,454	2,561	4,555	902	105	606	2,443	1,850	247	4,674	473	115	20,759	7,485	1,613	57	151	54	343	.247	.321	.406	.727
17	Diamondbacks	276	270	.505	546	18,347	2,638	4,563	924	117	634	2,506	1,856	231	4,299	439	97	20,732	7,623	1,675	109	189	49	371	.249	.322	.415	.738
18	Giants	273	274	.499	547	18,278	2,333	4,300	865	70	592	2,234	1,820	248	4,921	225	67	20,541	7,081	1,527	44	151	53	382	.235	.311	.387	.698
19	Tigers	270	278	.493	548	18,396	2,210	4,331	819	113	510	2,117	1,570	185	4,904	229	77	20,314	6,906	1,442	31	132	35	342	.235	.300	.375	.675
20	Red Sox	267	283	.485	550	18,906	2,561	4,833	1,122	69	606	2,453	1,674	233	4,903	364	103	20,986	7,911	1,797	35	138	81	391	.256	.322	.418	.740
21	Rangers	265	282	.484	547	18,508	2,476	4,515	841	59	667	2,367	1,701	175	4,642	359	99	20,544	7,475	1,567	29	131	52	311	.244	.312	.404	.715
22	Reds	251	298	.457	549	18,314	2,410	4,378	867	91	592	2,296	1,722	291	4,949	512	146	20,498	7,203	1,550	52	119	27	351	.239	.313	.393	.706
23	Royals	239	308	.437	547	18,328	2,255	4,502	870	128	507	2,176	1,444	192	4,268	449	134	20,212	7,149	1,505	71	177	50	319	.246	.305	.390	.695
24	Marlins	238	308	.436	546	18,453	2,129	4,514	849	74	511	2,028	1,455	191	4,618	381	112	20,291	7,044	1,434	63	129	50	435	.245	.305	.382	.686
25	Angels	237	310	.433	547	18,299	2,252	4,299	780	79	674	2,150	1,606	244	5,070	307	118	20,321	7,259	1,533	51	121	65	365	.235	.303	.397	.700