Since 1963, the New York Yankees have the most wins by a team, with 5,487 wins.

Interpreted as:

most regular-season wins by a team in MLB since 1963

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	5,487	4,341	.558	9,839	335,867	46,689	87,899	15,448	1,598	10,803	44,314	35,032	2,787	59,160	5,689	2,410	378,901	138,952	27,849	2,338	2,877	2,465	7,931	.262	.334	.414	.748
2	Dodgers	5,399	4,447	.548	9,852	334,351	42,370	85,761	14,608	1,832	8,884	39,922	32,145	2,536	61,580	6,799	2,976	376,212	130,685	25,324	4,521	2,659	3,283	7,068	.256	.324	.391	.715
3	Red Sox	5,240	4,602	.532	9,843	339,363	47,754	91,086	18,333	1,870	10,347	45,235	34,444	2,856	60,813	4,381	2,202	382,011	144,200	30,550	2,405	2,943	2,687	8,301	.268	.338	.425	.763
4	Cardinals	5,210	4,624	.530	9,843	335,543	43,394	87,758	15,891	2,285	7,989	40,822	31,756	2,670	60,654	7,378	3,144	376,737	132,186	26,165	4,004	2,764	3,311	7,334	.262	.328	.394	.722
5	Braves	5,122	4,707	.521	9,838	334,623	43,485	86,007	15,280	1,660	9,882	41,095	32,363	2,432	62,115	5,294	2,744	375,966	134,253	26,822	4,055	2,493	3,163	7,556	.257	.325	.401	.726
6	Giants	5,065	4,783	.514	9,851	334,648	42,531	84,887	15,166	2,153	8,943	39,969	32,830	2,599	63,468	5,455	2,727	376,930	131,188	26,262	4,242	2,611	3,614	7,322	.254	.323	.392	.715
7	Reds	5,024	4,819	.510	9,852	334,944	43,806	85,933	16,047	1,955	9,634	41,257	32,732	2,835	66,263	7,464	3,002	377,092	134,792	27,636	3,947	2,634	3,228	7,022	.257	.326	.402	.728
8	Orioles	5,006	4,815	.510	9,826	335,085	44,068	86,139	15,615	1,486	10,448	41,781	32,703	2,730	60,924	5,109	2,373	375,939	136,070	27,549	2,675	2,746	2,309	7,842	.257	.326	.406	.732
9	Astros	4,962	4,884	.504	9,849	334,190	42,102	85,233	15,712	2,124	8,304	39,630	31,813	2,854	62,009	7,104	3,100	375,486	130,105	26,140	3,952	2,677	3,107	7,263	.255	.323	.389	.712
10	Athletics	4,957	4,885	.504	9,844	333,121	43,544	83,482	15,121	1,665	9,654	41,013	34,332	2,826	63,711	6,791	2,866	375,807	130,895	26,440	2,775	2,753	2,039	7,451	.251	.323	.393	.716
11	Phillies	4,937	4,907	.502	9,849	335,511	42,950	85,503	15,858	2,311	8,971	40,454	32,855	2,736	65,752	6,261	2,514	377,425	132,896	27,140	3,678	2,645	3,360	6,918	.255	.324	.396	.720
12	Twins	4,889	4,950	.497	9,845	337,400	44,543	88,708	16,406	2,180	8,860	41,951	31,385	2,868	60,084	5,249	2,660	377,134	136,054	27,446	2,677	2,804	2,411	7,987	.263	.328	.403	.732
13	Guardians	4,884	4,939	.497	9,828	335,376	44,085	87,178	15,797	1,708	9,390	41,602	32,161	2,789	59,569	6,237	3,008	376,209	134,561	26,895	2,963	2,920	2,284	7,683	.260	.327	.401	.728
14	Angels	4,878	4,967	.495	9,847	334,169	42,538	85,594	14,813	1,751	8,867	40,035	30,986	2,757	60,603	5,959	3,042	373,973	130,510	25,431	3,374	2,687	2,417	7,644	.256	.322	.391	.713
15	White Sox	4,840	4,991	.492	9,841	334,481	43,173	86,231	15,006	1,910	9,324	40,826	30,608	2,886	60,004	5,942	2,918	373,953	133,029	26,240	3,195	2,783	2,176	7,527	.258	.323	.398	.721
16	Tigers	4,817	5,023	.490	9,845	335,826	44,114	86,558	15,169	2,241	10,112	41,780	32,157	2,576	63,428	4,706	2,551	375,868	136,545	27,522	2,589	2,720	2,142	7,534	.258	.325	.407	.732
17	Cubs	4,801	5,032	.488	9,846	335,460	42,790	85,606	15,485	2,095	9,434	40,324	31,479	2,676	64,614	5,289	2,695	376,118	133,583	27,014	3,942	2,561	3,090	7,179	.255	.322	.398	.720
18	Mets	4,798	5,039	.488	9,844	333,024	40,668	83,272	14,946	1,774	8,425	38,299	31,737	2,818	63,846	5,811	2,686	374,077	127,041	25,145	3,928	2,570	3,108	7,321	.250	.318	.381	.700
19	Pirates	4,786	5,046	.487	9,841	336,044	41,750	86,678	15,866	2,457	8,026	39,371	29,506	2,904	63,783	6,201	2,921	375,124	131,536	26,349	3,946	2,724	3,260	7,146	.258	.321	.391	.712
20	Rangers	4,713	5,119	.479	9,837	335,997	44,498	86,794	15,528	1,808	9,927	42,050	31,821	2,656	63,355	5,751	2,744	376,039	135,719	27,263	2,819	2,746	2,194	7,528	.258	.325	.404	.729
21	Brewers	4,324	4,548	.487	8,876	301,308	39,466	77,164	14,382	1,755	8,693	37,389	28,996	2,706	58,796	5,962	2,727	338,584	121,135	24,830	3,160	2,414	2,157	6,605	.256	.325	.402	.727
22	Nationals	4,280	4,588	.483	8,872	300,073	37,167	76,144	14,683	1,788	7,590	34,931	28,218	2,617	57,075	6,536	2,771	337,067	117,173	24,061	3,877	2,282	2,880	6,490	.254	.321	.390	.712
23	Royals	4,226	4,639	.477	8,867	303,284	38,782	79,639	14,888	2,284	6,990	36,600	25,968	2,455	52,029	7,076	2,893	336,737	120,065	24,162	2,364	2,666	1,865	6,771	.263	.323	.396	.719
24	Padres	4,148	4,728	.467	8,878	300,112	35,975	74,840	13,243	1,757	7,246	33,831	28,570	2,122	59,364	5,997	2,603	336,756	113,335	22,246	3,709	2,243	2,685	6,492	.249	.317	.378	.695
25	Blue Jays	3,777	3,805	.498	7,585	259,870	35,055	67,575	13,505	1,491	8,239	33,249	24,095	2,421	48,864	4,567	1,962	290,003	108,779	23,235	1,496	2,121	1,397	5,916	.260	.326	.419	.745