Since 1999, the New York Yankees have the most wins by a team, with 2,478 wins.

Interpreted as:

most regular-season wins by an MLB team since 1999

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	2,478	1,790	.581	4,270	145,842	21,813	38,221	7,212	544	5,828	20,895	15,954	1,682	31,302	2,648	855	165,306	64,005	13,584	621	1,207	855	3,436	.262	.339	.439	.778
2	Dodgers	2,409	1,863	.564	4,272	145,135	19,883	37,398	7,295	727	4,828	18,974	14,727	1,591	31,080	2,566	941	163,962	60,631	12,850	1,353	1,156	1,128	3,161	.258	.330	.418	.748
3	Cardinals	2,332	1,936	.546	4,268	145,097	20,021	37,959	7,442	629	4,684	19,049	14,188	1,738	30,494	2,114	888	163,701	60,711	12,755	1,487	1,191	1,166	3,303	.262	.332	.418	.751
4	Braves	2,331	1,937	.546	4,269	145,709	19,923	37,786	7,553	643	4,859	19,026	14,352	1,397	31,994	2,187	868	163,972	61,202	13,055	1,436	1,078	1,127	3,270	.259	.329	.420	.749
5	Red Sox	2,328	1,943	.545	4,271	148,268	21,750	39,873	8,871	703	5,007	20,727	15,020	1,567	31,406	2,254	765	166,671	65,171	14,581	533	1,283	1,003	3,384	.269	.340	.440	.779
6	Guardians	2,231	2,038	.523	4,269	145,528	20,159	37,654	7,801	677	4,663	19,215	14,428	1,663	31,023	2,659	943	163,777	60,798	13,141	898	1,260	831	3,211	.259	.330	.418	.748
7	Giants	2,219	2,050	.520	4,270	145,229	18,860	37,090	7,456	887	4,196	17,952	13,938	1,401	30,625	1,944	828	163,190	58,908	12,539	1,413	1,209	1,288	3,321	.255	.324	.406	.730
8	Astros	2,213	2,057	.518	4,271	145,235	19,717	37,491	7,489	655	4,898	18,812	13,945	1,621	31,107	2,513	1,005	163,188	60,984	13,042	1,231	1,156	885	3,392	.258	.328	.420	.747
9	Athletics	2,193	2,077	.514	4,270	145,278	19,581	36,318	7,497	609	4,780	18,661	14,949	1,535	31,426	2,024	676	163,492	59,373	12,886	583	1,147	652	3,352	.250	.324	.409	.733
10	Phillies	2,192	2,079	.513	4,271	145,978	19,739	37,285	7,477	855	4,772	18,832	14,525	1,586	32,635	2,779	745	164,428	60,788	13,104	1,280	1,059	1,180	2,959	.255	.327	.416	.744
11	Angels	2,176	2,096	.509	4,272	145,616	19,572	37,671	7,161	688	4,632	18,634	13,006	1,541	29,979	2,815	1,120	162,210	60,104	12,481	867	1,180	915	3,280	.259	.324	.413	.736
12	Mets	2,156	2,115	.505	4,271	144,799	18,921	36,683	7,238	678	4,554	18,067	14,175	1,711	31,304	2,644	883	163,139	58,939	12,470	1,361	1,093	1,120	3,198	.253	.325	.407	.732
13	Blue Jays	2,155	2,116	.505	4,271	146,284	20,351	37,925	7,956	600	5,235	19,459	13,769	1,557	30,591	2,101	783	163,368	62,786	13,791	610	1,148	635	3,422	.259	.327	.429	.756
14	Mariners	2,144	2,128	.502	4,272	145,662	18,956	36,895	6,943	605	4,585	18,052	13,578	1,588	32,120	2,789	992	162,769	58,803	12,133	826	1,115	827	3,060	.253	.321	.404	.725
15	Brewers	2,131	2,140	.499	4,272	144,533	19,201	36,440	7,327	715	4,890	18,332	14,230	1,765	34,334	2,870	977	162,906	59,867	12,932	1,332	1,046	975	3,193	.252	.325	.414	.739
16	Cubs	2,128	2,142	.498	4,271	145,138	19,277	36,815	7,391	769	4,840	18,371	14,030	1,640	33,275	2,182	904	163,259	60,264	13,000	1,394	1,057	998	3,122	.254	.324	.415	.739
17	Twins	2,117	2,154	.496	4,272	146,370	19,639	38,009	7,677	811	4,370	18,622	13,625	1,493	31,024	2,293	947	163,398	60,418	12,858	723	1,187	787	3,343	.260	.327	.413	.739
18	Rangers	2,113	2,160	.495	4,273	146,782	20,896	38,390	7,575	699	5,296	19,905	13,397	1,530	31,673	2,633	948	163,681	63,251	13,570	771	1,201	739	3,089	.262	.327	.431	.758
19	Rays	2,105	2,165	.493	4,270	145,116	19,080	36,784	7,329	820	4,523	18,162	13,814	1,672	33,303	3,223	1,188	162,448	59,322	12,672	700	1,146	671	2,974	.253	.323	.409	.732
20	Diamondbacks	2,102	2,170	.492	4,272	145,760	19,631	37,168	7,659	1,049	4,600	18,727	14,235	1,418	32,332	2,512	892	163,944	60,725	13,308	1,309	1,222	1,073	3,033	.255	.325	.417	.741
21	Padres	2,052	2,221	.480	4,273	144,106	18,064	35,701	6,910	757	4,100	17,171	14,222	1,320	32,868	2,724	969	162,018	56,425	11,767	1,259	1,111	900	3,093	.248	.319	.392	.710
22	White Sox	2,046	2,225	.479	4,272	145,454	19,275	37,418	7,079	605	4,919	18,474	12,443	1,590	31,070	2,383	1,045	161,499	60,464	12,603	929	1,083	576	3,318	.257	.320	.416	.736
23	Reds	2,040	2,233	.477	4,275	144,981	19,175	36,557	7,240	656	4,903	18,295	14,079	1,776	33,677	2,755	1,026	163,355	59,818	12,799	1,470	1,049	979	3,019	.252	.324	.413	.736
24	Nationals	2,012	2,258	.471	4,270	144,345	18,564	36,811	7,500	728	4,264	17,655	13,539	1,527	31,333	2,624	1,042	162,033	58,559	12,492	1,544	1,078	1,078	3,265	.255	.323	.406	.729
25	Tigers	1,997	2,269	.468	4,266	146,139	19,090	38,003	7,293	1,008	4,461	18,253	12,544	1,353	31,999	1,964	904	161,970	60,695	12,762	774	1,160	700	3,261	.260	.322	.415	.737