The Pittsburgh Pirates are 97-129 versus the Astros since 2000.

	TEAM	OPP	REC	W%	G	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Pirates	Astros	97-129	.429	226	97	129	7,637	881	1,906	363	36	206	836	599	93	1,679	101	47	8,474	2,959	605	87	58	49	164	.250	.310	.387	.697
2	Pirates	Diamondbacks	70-92	.432	162	70	92	5,627	686	1,444	308	29	144	650	461	46	1,308	78	45	6,221	2,242	481	52	35	43	115	.257	.316	.398	.715
3	Pirates	Nationals	76-86	.469	162	76	86	5,401	690	1,357	283	23	144	666	487	71	1,145	78	44	6,061	2,118	450	55	47	45	122	.251	.319	.392	.711
4	Pirates	Mets	74-90	.451	164	74	90	5,556	696	1,410	257	27	142	664	499	67	1,237	91	30	6,223	2,147	426	59	42	38	128	.254	.321	.386	.707
5	Pirates	Marlins	85-78	.521	163	85	78	5,521	681	1,407	298	39	108	644	542	69	1,289	106	41	6,229	2,107	445	52	45	53	133	.255	.327	.382	.708
6	Pirates	Braves	69-97	.416	166	69	97	5,619	620	1,375	284	26	122	589	494	63	1,290	94	43	6,274	2,077	432	66	32	63	133	.245	.311	.370	.681
7	Pirates	Padres	69-93	.426	162	69	93	5,509	666	1,367	263	29	137	630	507	93	1,277	95	36	6,194	2,099	429	50	35	27	108	.248	.320	.381	.701
8	Pirates	Reds	207-219	.486	426	207	219	14,321	1,773	3,607	737	72	417	1,695	1,322	199	3,251	202	109	16,120	5,739	1,226	161	117	86	271	.252	.321	.401	.722
9	Pirates	Cardinals	167-253	.398	420	167	253	14,273	1,729	3,627	698	89	365	1,656	1,220	184	2,963	145	73	15,930	5,598	1,152	141	112	70	361	.254	.319	.392	.711
10	Pirates	Cubs	185-236	.439	422	185	236	14,196	1,738	3,434	684	85	399	1,654	1,395	170	3,439	268	101	15,985	5,485	1,168	121	103	86	292	.242	.315	.386	.701
11	Pirates	Brewers	185-234	.442	419	185	234	14,198	1,759	3,553	705	78	445	1,683	1,326	164	3,202	205	108	15,902	5,749	1,228	130	84	96	283	.250	.320	.405	.725
12	Pirates	Rockies	88-76	.537	164	88	76	5,599	804	1,521	304	47	151	771	543	71	1,093	88	39	6,321	2,372	502	59	49	44	132	.272	.341	.424	.765
13	Pirates	Royals	18-19	.486	37	18	19	1,265	151	327	66	7	33	140	113	12	278	23	18	1,409	506	106	11	8	5	26	.258	.323	.400	.723
14	Pirates	Tigers	44-39	.530	83	44	39	2,833	372	750	141	17	73	352	241	28	645	48	24	3,151	1,144	231	20	29	15	68	.265	.325	.404	.729
15	Pirates	Phillies	81-83	.494	164	81	83	5,508	644	1,338	295	33	134	617	452	66	1,297	97	40	6,106	2,101	462	50	30	42	114	.243	.306	.381	.688
16	Pirates	Twins	15-21	.417	36	15	21	1,231	155	303	63	5	39	145	113	11	265	19	4	1,371	493	107	7	9	4	19	.246	.313	.400	.714
17	Pirates	Guardians	21-27	.438	48	21	27	1,640	199	393	70	8	50	191	141	11	396	37	10	1,820	629	128	23	5	9	36	.240	.303	.384	.687
18	Pirates	Dodgers	59-110	.349	169	59	110	5,705	690	1,385	265	20	167	660	499	61	1,317	95	42	6,342	2,191	452	43	34	32	112	.243	.309	.384	.693
19	Pirates	Giants	75-78	.490	153	75	78	5,198	659	1,296	264	42	154	631	457	56	1,178	74	41	5,807	2,106	460	43	53	28	106	.249	.314	.405	.719
20	Pirates	White Sox	20-20	.500	40	20	20	1,340	174	351	74	8	29	167	103	15	301	22	9	1,477	528	111	7	12	4	30	.262	.319	.394	.713
21	Pirates	Angels	13-14	.481	27	13	14	951	130	257	57	3	37	121	77	12	192	14	9	1,051	431	97	8	3	6	18	.270	.332	.453	.785
22	Pirates	Athletics	7-17	.292	24	7	17	808	79	182	27	4	17	76	84	10	184	15	3	913	268	48	7	4	5	18	.225	.305	.332	.636
23	Pirates	Rangers	11-18	.379	29	11	18	1,002	116	257	52	5	19	110	70	13	232	24	7	1,098	376	76	7	6	4	16	.256	.312	.375	.687
24	Pirates	Red Sox	11-13	.458	24	11	13	791	85	181	34	4	21	80	69	11	167	11	7	882	286	59	4	7	1	18	.229	.297	.362	.659
25	Pirates	Blue Jays	8-16	.333	24	8	16	829	88	193	32	7	18	83	62	8	195	12	4	911	293	57	5	7	3	10	.233	.290	.353	.644