The Boston Red Sox put up their most runs in a game versus the White Sox on August 30, 1970, with 21 runs.

Interpreted as:

red sox most runs in a regular-season game vs white sox

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Red Sox	21	8/30/1970	BOS	@	CWS	W 21-11	47	22	5	1	2	21	10	0	5	2	0	57	35	8	0	0	1	1	.468	.561	.745	1.306
2	Red Sox	19	5/13/1947	BSA	vs	CWS	W 19-6	40	18	3	3	3	17	11	0	3	0	1	53	36	9	2			0	.450	.569	.900	1.469
3	Red Sox	19	8/27/1938	BSA	vs	CWS	W 19-6	46	22	6	1	1	17	6	0	3	0	0	53	33	8	1				.478	.538	.717	1.256
4	Red Sox	18	5/16/1939	BSA	vs	CWS	W 18-4	42	19	5	0	1	17	6	1	1	0	0	49	27	6	0			1	.452	.531	.643	1.173
5	Red Sox	17	6/26/1999	BOS	vs	CWS	W 17-1	38	14	5	0	5	17	4	1	6	0	0	44	34	10	0	1	0	0	.368	.432	.895	1.327
6	Red Sox	17	6/4/1950	BSA	vs	CWS	W 17-7	45	21	4	1	0	17	9	0	3	0	0	54	27	5	0		0	1	.467	.556	.600	1.156
7	Red Sox	17	6/5/1929	BSA	vs	CWS	W 17-2	42	23	8	1	2	16	2	0	5	0	1	47	39	11	3				.548	.568	.929	1.497
8	Red Sox	16	5/26/2022	BOS	@	CWS	W 16-7	46	19	4	0	3	14	5	0	12	1	0	51	32	7	0	0	0	1	.413	.471	.696	1.166
9	Red Sox	16	5/24/2022	BOS	@	CWS	W 16-3	45	19	5	0	4	16	5	0	12	0	0	51	36	9	0	1	0	0	.422	.471	.800	1.271
10	Red Sox	16	5/5/1988	BOS	vs	CWS	W 16-3	40	18	6	0	1	15	6	0	2	0	0	47	27	7	1	0	0	1	.450	.522	.675	1.197
11	Red Sox	16	4/30/1936	BSA	vs	CWS	W 16-4	41	18	5	2	0	13	12	0	3	0	0	53	27	7	0				.439	.566	.659	1.225
12	Red Sox	16	7/18/1934	BSA	@	CWS	W 16-3	40	15	2	0	4	16	5	0	5	0	0	47	29	6	2				.375	.444	.725	1.169
13	Red Sox	16	5/13/1921	BSA	@	CWS	W 16-8	41	15	3	0	2	16	8	0	4	3	0	50	24	5	1				.366	.469	.585	1.055
14	Red Sox	16	5/26/1908	BOS	vs	CWS	W 16-5	37	17	0	1	0	15	2	2	2	3		44	19	1	3				.459	.512	.514	1.026
15	Red Sox	15	5/4/2019	BOS	@	CWS	W 15-2	48	21	5	0	4	14	5	0	8	0	0	53	38	9	0	0	0	2	.438	.491	.792	1.282
16	Red Sox	15	7/5/1998	BOS	vs	CWS	W 15-14	43	20	7	0	2	15	4	2	1	0	0	52	33	9	1	2	0	0	.465	.510	.767	1.277
17	Red Sox	15	7/3/1998	BOS	vs	CWS	W 15-2	42	17	2	1	3	13	3	1	6	1	0	47	30	6	0	1	0	0	.405	.447	.714	1.161
18	Red Sox	15	6/12/1949	BSA	@	CWS	W 15-3	40	14	3	0	3	14	5	1	2	2	0	46	26	6	0			2	.350	.435	.650	1.085
19	Red Sox	15	7/27/1932	BSA	@	CWS	W 15-5	45	18	3	1	1	13	7	1	2	4	0	53	26	5	0				.400	.491	.578	1.068
20	Red Sox	15	8/14/1919	BSA	@	CWS	W 15-6	45	20	3	2	1	14	2	0	4	1		47	30	6	0				.444	.468	.667	1.135
21	Red Sox	14	6/6/2024	BOS	@	CWS	W 14-2	49	24	3	0	3	14	5	1	5	0	0	56	36	6	0	1	0	1	.490	.536	.735	1.270
22	Red Sox	14	8/25/2007	BOS	@	CWS	W 14-2	41	15	4	0	0	13	10	2	6	0	0	53	19	4	0	0	1	2	.366	.509	.463	.973
23	Red Sox	14	6/28/1999	BOS	vs	CWS	W 14-1	45	21	2	1	2	14	3	1	7	0	0	49	31	5	0	0	0	1	.467	.510	.689	1.199
24	Red Sox	14	8/18/1987	BOS	@	CWS	W 14-8	43	20	1	1	1	13	5	1	6	4	1	52	26	3	3	0	0	0	.465	.531	.605	1.135
25	Red Sox	14	7/31/1984	BOS	@	CWS	W 14-4	40	14	4	1	3	14	11	0	1	2	0	51	29	8	0	0	1	1	.350	.490	.725	1.215