The St. Louis Browns have scored the most runs by a team in a game on May 12, with 22 runs against the Orioles on May 12, 1887.

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Browns	22	5/12/1887	STL	vs	BAL	W 22-14
2	Rangers	19	5/12/1986	TEX	@	CLE	W 19-2	43	22	3	0	1	18	9	1	5	0	3	55	28	4	1	1	0	2	.512	.593	.651	1.244
3	Metropolitans	19	5/12/1887	NYM	@	CIN	W 19-6
4	Beaneaters	19	5/12/1887	BSN	vs	WSH	W 19-7
5	Reds	18	5/12/1911	CIN	@	BSN	W 18-8	50	21	3	2	0		4	1	2	0		55	28	5	0				.420	.473	.560	1.033
6	Phillies	18	5/12/1893	PHI	vs	NYG	W 18-6
7	Grooms	18	5/12/1891	BKN	@	CNN	W 18-7
8	Red Caps	18	5/12/1877	BOS	@	CWS	W 18-9
9	Cubs	17	5/12/2014	CHC	@	STL	W 17-5	45	20	5	1	2	16	1	1	4	0	0	50	33	8	1	2	0	0	.444	.449	.733	1.182
10	Royals	17	5/12/1976	KCR	vs	MIN	W 17-5	43	22	5	1	0	16	4	0	5	1	0	50	29	6	0	3	0	1	.512	.520	.674	1.194
11	Athletics	17	5/12/1911	PHA	@	SLA	W 17-13	42	19	2	0	0		4	3	0	6		51	21	2	2				.452	.531	.500	1.031
12	Bridegrooms	17	5/12/1890	BKN	@	PHN	W 17-7
13	Grays	17	5/12/1887	BKN	@	CLE	W 17-12
14	Quakers	17	5/12/1885	PHN	vs	DET	W 17-8
15	Rangers	16	5/12/2001	TEX	@	CWS	W 16-6	42	14	2	0	4	16	8	0	6	0	0	50	28	6	0	0	0	1	.333	.440	.667	1.107
16	Angels	16	5/12/1997	ANA	vs	CWS	W 16-8	40	18	1	0	1	15	6	1	2	1	0	50	22	2	1	2	0	1	.450	.510	.550	1.060
17	Beaneaters	16	5/12/1883	BSN	@	BUF	W 16-5
18	Yankees	15	5/12/2022	NYY	@	CWS	W 15-7	40	15	2	1	4	15	7	0	14	0	0	48	31	7	0	1	0	1	.375	.458	.775	1.233
19	Astros	15	5/12/2019	HOU	vs	TEX	W 15-5	43	18	3	1	4	14	2	0	8	0	0	45	35	8	0	0	0	0	.419	.444	.814	1.258
20	Rockies	15	5/12/2000	COL	vs	SFG	W 15-7	37	15	4	0	2	13	5	0	9	3	0	44	25	6	2	0	1	0	.405	.476	.676	1.152
21	Tigers	15	5/12/1987	DET	vs	CAL	W 15-2	43	18	3	0	2	13	6	0	6	2	0	50	27	5	0	1	0	0	.419	.480	.628	1.108
22	Dodgers	15	5/12/1974	LAD	@	SDP	W 15-9	59	23	6	0	1	14	4	0	3	2	1	64	32	7	1	0	3	1	.390	.429	.542	.971
23	Cardinals	15	5/12/1937	SLN	@	PHN	W 15-3	45	20	6	2	3	14	4	0	1	3	0	49	39	11	0			1	.444	.490	.867	1.356
24	Browns	15	5/12/1929	SLA	vs	BSA	W 15-3	39	18	1	0	2	11	3	0	1	1	0	43	25	3	1				.462	.500	.641	1.141
25	Red Sox	15	5/12/1928	BSA	vs	SLA	W 15-2	36	16	2	1	1	15	6	0	0	1	1	47	23	4	5				.444	.524	.639	1.163