4 teams are tied for the most runs in a game in the 16th inning, with 5 runs. The first three are the Tampa Bay Rays on July 3, 2018, the Minnesota Twins on August 16, 2005 and the Houston Astros on April 8, 1988.
Interpreted as:
team most runs in a regular-season game in the 16th inning| TEAM | R | DATE | TM | OPP | AB | H | 2B | 3B | HR | RBI | BB | HBP | SO | PA | TB | XBH | SH | SF | IBB | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Rays | 5 | 7/3/2018 |  TBR | @ |  MIA | 6 | 4 | 2 | 0 | 0 | 5 | 2 | 1 | 0 | 9 | 6 | 2 | 0 | 0 | 1 | .667 | .778 | 1.000 | 1.778 |
| 2 |  | Twins | 5 | 8/16/2005 |  MIN | @ |  CWS | 8 | 5 | 1 | 0 | 0 | 5 | 2 | 0 | 0 | 10 | 6 | 1 | 0 | 0 | 1 | .625 | .700 | .750 | 1.450 |
| 3 |  | Astros | 5 | 4/8/1988 |  HOU | @ |  CIN | 6 | 5 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 9 | 5 | 0 | 1 | 1 | 0 | .833 | .750 | .833 | 1.583 |
| 4 |  | Yankees | 5 | 5/18/1976 |  NYY | @ |  CLE | 5 | 2 | 1 | 0 | 0 | 4 | 3 | 0 | 1 | 10 | 3 | 1 | 1 | 1 | 1 | .400 | .556 | .600 | 1.156 |
| 5 |  | Rangers | 4 | 6/11/1986 |  TEX | @ |  MIN | 8 | 5 | 2 | 0 | 1 | 4 | 1 | 0 | 2 | 9 | 10 | 3 | 0 | 0 | 0 | .625 | .667 | 1.250 | 1.917 |
| 6 |  | Angels | 4 | 4/8/1982 |  CAL | @ |  OAK | 6 | 4 | 0 | 0 | 1 | 3 | 1 | 0 | 0 | 8 | 7 | 1 | 0 | 1 | 0 | .667 | .625 | 1.167 | 1.792 |
| 7 |  | Expos | 4 | 5/2/1976 |  MON | @ | CIN | 6 | 3 | 2 | 0 | 0 | 4 | 2 | 0 | 1 | 8 | 5 | 2 | 0 | 0 | 1 | .500 | .625 | .833 | 1.458 |
| 8 |  | Rockies | 3 | 9/24/2019 |  COL | @ |  SFG | 6 | 4 | 1 | 0 | 1 | 3 | 1 | 0 | 2 | 8 | 8 | 2 | 1 | 0 | 0 | .667 | .714 | 1.333 | 2.048 |
| 9 |  | Giants | 3 | 6/14/2018 | SFG | @ | MIA | 5 | 3 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | .600 | .571 | .600 | 1.171 |
| 10 | | Yankees | 3 | 7/15/2017 | NYY | @ |  BOS | 5 | 4 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 8 | 5 | 1 | 1 | 1 | 1 | .800 | .714 | 1.000 | 1.714 |
| 11 |  | Blue Jays | 3 | 4/5/2012 |  TOR | @ | CLE | 5 | 1 | 0 | 0 | 1 | 3 | 1 | 0 | 1 | 6 | 4 | 1 | 0 | 0 | 0 | .200 | .333 | .800 | 1.133 |
| 12 |  | Tigers | 3 | 7/3/2009 |  DET | @ | MIN | 8 | 5 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 8 | 6 | 1 | 0 | 0 | 0 | .625 | .625 | .750 | 1.375 |
| 13 |  | Cubs | 3 | 6/22/1996 |  CHC | @ |  SDP | 6 | 2 | 1 | 0 | 1 | 2 | 0 | 0 | 1 | 6 | 6 | 2 | 0 | 0 | 0 | .333 | .333 | 1.000 | 1.333 |
| 14 |  | Pirates | 3 | 8/10/1992 |  PIT | @ |  NYM | 6 | 4 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 8 | 4 | 0 | 1 | 0 | 1 | .667 | .714 | .667 | 1.381 |
| 15 | | Angels | 3 | 7/7/1986 | CAL | @ |  MIL | 5 | 2 | 0 | 2 | 0 | 3 | 2 | 0 | 0 | 7 | 6 | 2 | 0 | 0 | 0 | .400 | .571 | 1.200 | 1.771 |
| 16 |  | Mariners | 3 | 4/11/1982 |  SEA | @ | OAK | 5 | 2 | 1 | 0 | 0 | 3 | 2 | 0 | 0 | 7 | 3 | 1 | 0 | 0 | 1 | .400 | .571 | .600 | 1.171 |
| 17 |  | Dodgers | 2 | 8/25/2021 |  LAD | @ |  SDP | 5 | 2 | 1 | 0 | 1 | 2 | 1 | 0 | 0 | 6 | 6 | 2 | 0 | 0 | 1 | .400 | .500 | 1.200 | 1.700 |
| 18 |  | Orioles | 2 | 7/25/2019 |  BAL | @ |  LAA | 5 | 2 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 5 | 5 | 1 | 0 | 0 | 0 | .400 | .400 | 1.000 | 1.400 |
| 19 |  | Marlins | 2 | 7/3/2018 | MIA | vs | TBR | 5 | 3 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | .600 | .571 | .600 | 1.171 |
| 20 |  | Nationals | 2 | 6/24/2014 |  WSH | @ |  MIL | 5 | 2 | 0 | 0 | 1 | 2 | 0 | 0 | 2 | 5 | 5 | 1 | 0 | 0 | 0 | .400 | .400 | 1.000 | 1.400 |
| 21 |  | Diamondbacks | 2 | 8/18/2013 |  ARI | @ | PIT | 5 | 2 | 1 | 0 | 0 | 2 | 1 | 0 | 1 | 6 | 3 | 1 | 0 | 0 | 0 | .400 | .500 | .600 | 1.100 |
| 22 |  | White Sox | 2 | 6/5/2013 | CWS | @ |  SEA | 6 | 3 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 7 | 3 | 0 | 0 | 0 | 1 | .500 | .571 | .500 | 1.071 |
| 23 |  | Astros | 2 | 8/24/2010 |  HOU | @ |  PHI | 5 | 2 | 0 | 0 | 0 | 2 | 2 | 1 | 1 | 8 | 2 | 0 | 0 | 0 | 2 | .400 | .625 | .400 | 1.025 |
| 24 |  | Rangers | 2 | 8/18/2003 |  TEX | @ | DET | 7 | 4 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 7 | 8 | 2 | 0 | 0 | 0 | .571 | .571 | 1.143 | 1.714 |
| 25 |  | Astros | 2 | 8/20/1999 |  HOU | @ |  FLA | 4 | 2 | 1 | 0 | 1 | 2 | 2 | 0 | 1 | 7 | 6 | 2 | 0 | 1 | 1 | .500 | .571 | 1.500 | 2.071 |
Results may be incomplete. StatMuse has complete event-level data for runs going back to the 1974 season.
Some of the information used here was obtained free of charge from Retrosheet.
Brewers 
Astros 
STL 
