The New York Yankees had the highest run differential by a team in 1947, with a differential of 226 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	GIDP	AVG	OBP	SLG	OPS
1	Yankees	226	1947	155	.630	97	57	5,308	794	1,439	230	72	115	748	610	27	581	27	23	6,031	2,158	417	86	122	.271	.349	.407	.756
2	Cardinals	146	1947	156	.578	89	65	5,422	780	1,462	235	65	115	718	612	29	511	28		6,131	2,172	415	68	136	.270	.347	.401	.747
3	Dodgers	105	1947	155	.610	94	60	5,249	774	1,428	241	50	83	719	732	29	561	88		6,125	2,018	374	115	87	.272	.364	.384	.749
4	Indians	99	1947	157	.519	80	74	5,367	687	1,392	234	51	112	649	501	14	607	29	25	5,975	2,064	397	93	107	.259	.324	.385	.709
5	Braves	79	1947	154	.558	86	68	5,253	701	1,444	265	42	85	645	558	14	502	58		5,954	2,048	392	129	130	.275	.346	.390	.736
6	Tigers	72	1947	158	.552	85	69	5,276	714	1,363	234	42	103	662	761	13	563	52	60	6,147	1,990	379	97	130	.258	.353	.377	.730
7	Giants	69	1947	155	.526	81	73	5,343	830	1,446	220	48	221	790	494	23	570	29		5,924	2,425	489	64	114	.271	.335	.454	.789
8	Red Sox	51	1947	157	.539	83	71	5,322	720	1,412	206	54	103	674	667	16	589	41	35	6,100	2,035	363	95	140	.265	.349	.382	.731
9	Athletics	19	1947	156	.506	78	76	5,198	633	1,311	218	52	61	581	605	24	563	37	33	5,971	1,816	331	144	117	.252	.333	.349	.682
10	Pirates	-71	1947	156	.403	62	92	5,307	744	1,385	216	44	156	699	606	24	684	30		6,007	2,157	416	70	136	.261	.339	.406	.746
11	Reds	-74	1947	154	.474	73	81	5,299	681	1,372	242	43	95	637	539	21	530	46		5,954	1,985	380	95	97	.259	.330	.375	.704
12	Phillies	-98	1947	155	.403	62	92	5,256	589	1,354	210	52	60	544	464	26	593	60		5,828	1,848	322	82	119	.258	.321	.352	.673
13	White Sox	-108	1947	155	.455	70	84	5,274	553	1,350	211	41	53	519	491	15	528	91	57	5,836	1,802	305	56	142	.256	.321	.342	.663
14	Cubs	-155	1947	155	.448	69	85	5,305	567	1,373	231	48	71	540	469	19	578	22		5,857	1,913	350	64	112	.259	.321	.361	.682
15	Senators	-179	1947	154	.416	64	90	5,112	496	1,234	186	48	42	459	525	8	534	53	51	5,717	1,642	276	72	131	.241	.313	.321	.634
16	Browns	-180	1947	154	.383	59	95	5,145	564	1,238	189	52	90	526	583	15	663	69	49	5,819	1,801	331	76	118	.241	.320	.350	.670