The Los Angeles Dodgers had the highest run differential by a team in 1974, with a differential of 237 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	237	1974	162	.630	102	60	5,557	798	1,511	231	34	139	744	597	28	820	149	75	6,332	2,227	404	86	64	95	117	.272	.342	.401	.743
2	Reds	145	1974	163	.605	98	64	5,535	776	1,437	271	35	135	714	693	30	940	146	49	6,372	2,183	441	68	46	87	121	.260	.343	.394	.737
3	Athletics	138	1974	162	.556	90	72	5,331	689	1,315	205	37	132	637	568	38	876	164	93	6,048	1,990	374	60	51	48	108	.247	.321	.373	.694
4	Braves	98	1974	163	.543	88	74	5,533	661	1,375	202	37	120	599	571	24	772	72	44	6,279	2,011	359	109	42	78	124	.249	.319	.363	.683
5	Pirates	94	1974	162	.543	88	74	5,702	751	1,560	238	46	114	692	514	38	828	55	31	6,361	2,232	398	54	53	74	140	.274	.335	.391	.726
6	Yankees	48	1974	162	.549	89	73	5,524	671	1,451	220	30	101	637	515	21	690	53	35	6,181	2,034	351	49	72	52	122	.263	.324	.368	.692
7	Orioles	47	1974	162	.562	91	71	5,535	659	1,418	226	27	116	608	509	58	770	145	58	6,230	2,046	369	72	56	61	124	.256	.322	.370	.692
8	Red Sox	35	1974	162	.519	84	78	5,499	696	1,449	236	31	109	658	569	33	811	104	58	6,214	2,074	376	64	49	57	128	.264	.333	.377	.711
9	Cardinals	34	1974	161	.534	86	75	5,620	677	1,492	216	46	83	610	531	44	752	172	62	6,318	2,049	345	68	55	79	142	.265	.331	.365	.695
10	Astros	21	1974	162	.500	81	81	5,489	653	1,441	222	41	110	603	471	29	864	108	65	6,120	2,075	373	83	48	49	124	.263	.322	.378	.700
11	Royals	5	1974	162	.475	77	85	5,582	667	1,448	232	42	89	623	550	32	768	146	76	6,263	2,031	363	56	43	42	133	.259	.327	.364	.691
12	Expos	5	1974	161	.491	79	82	5,343	662	1,355	201	29	86	610	652	33	812	124	49	6,190	1,872	316	106	56	65	127	.254	.335	.350	.686
13	Twins	4	1974	163	.506	82	80	5,632	673	1,530	190	37	111	632	520	46	791	74	45	6,302	2,127	338	64	40	43	159	.272	.336	.378	.714
14	Rangers	-8	1974	161	.525	84	76	5,449	690	1,482	198	39	99	643	508	38	710	113	80	6,123	2,055	336	81	47	38	155	.272	.336	.377	.713
15	Brewers	-13	1974	162	.469	76	86	5,472	647	1,335	228	49	120	612	500	27	909	106	75	6,090	2,021	397	56	35	37	102	.244	.309	.369	.678
16	Phillies	-25	1974	162	.494	80	82	5,494	676	1,434	233	50	95	636	469	26	822	115	58	6,117	2,052	378	84	44	75	112	.261	.320	.373	.693
17	Indians	-32	1974	162	.475	77	85	5,474	662	1,395	201	19	131	616	432	26	756	79	68	6,019	2,027	351	56	31	31	135	.255	.311	.370	.681
18	White Sox	-37	1974	163	.500	80	80	5,577	684	1,492	225	23	135	633	519	26	858	64	53	6,235	2,168	383	70	43	40	156	.268	.330	.389	.719
19	Angels	-39	1974	163	.420	68	94	5,401	618	1,372	203	31	95	550	509	45	801	119	79	6,085	1,922	329	82	48	38	135	.254	.321	.356	.677
20	Mets	-74	1974	162	.438	71	91	5,468	572	1,286	183	22	96	538	597	29	735	43	23	6,226	1,801	301	87	45	56	148	.235	.311	.329	.641
21	Giants	-89	1974	162	.444	72	90	5,482	634	1,380	228	38	93	568	548	30	869	107	51	6,159	1,963	359	75	24	57	113	.252	.322	.358	.680
22	Tigers	-148	1974	162	.444	72	90	5,568	620	1,375	200	35	131	579	436	24	784	67	38	6,106	2,038	366	41	37	33	132	.247	.303	.366	.669
23	Cubs	-157	1974	162	.407	66	96	5,574	669	1,397	221	42	110	610	621	29	857	78	73	6,344	2,032	373	80	40	66	121	.251	.327	.365	.691
24	Padres	-289	1974	162	.370	60	102	5,415	541	1,239	196	27	99	506	564	20	900	85	45	6,117	1,786	322	83	35	52	105	.229	.302	.330	.632