Since 2021, the Los Angeles Dodgers have the most wins by a team, with 455 wins.

Interpreted as:

teams with the most regular-season wins since 2021

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	455	261	.635	716	24,355	3,801	6,214	1,284	112	1,034	3,663	2,722	332	6,042	446	95	27,704	10,824	2,430	53	242	135	430	.255	.335	.444	.780
2	Astros	415	298	.582	713	24,294	3,430	6,277	1,215	71	912	3,300	2,283	292	5,320	375	107	27,121	10,370	2,198	52	200	94	565	.258	.327	.427	.754
3	Braves	410	303	.575	713	24,191	3,497	6,122	1,227	75	1,073	3,362	2,268	280	6,269	383	109	26,963	10,718	2,375	51	173	87	471	.253	.322	.443	.765
4	Yankees	407	306	.571	713	23,738	3,365	5,711	1,019	60	1,039	3,208	2,735	260	6,199	402	122	26,974	9,967	2,118	48	193	112	574	.241	.323	.420	.743
5	Brewers	402	314	.561	716	23,898	3,265	5,703	1,103	89	816	3,114	2,591	300	6,358	610	141	27,023	9,432	2,008	73	161	93	492	.239	.319	.395	.714
6	Rays	401	314	.561	715	24,057	3,285	5,852	1,217	103	808	3,118	2,295	321	6,407	616	190	26,868	9,699	2,128	33	162	65	407	.243	.316	.403	.719
7	Phillies	392	323	.548	715	24,220	3,366	6,099	1,195	115	890	3,229	2,331	274	6,142	531	115	27,095	10,194	2,200	86	184	103	478	.252	.322	.421	.743
8	Giants	386	329	.540	715	23,922	3,164	5,698	1,146	96	838	3,026	2,440	315	6,435	297	82	26,945	9,550	2,080	80	188	98	499	.238	.315	.399	.714
9	Mariners	386	328	.541	714	23,819	3,110	5,518	1,054	59	877	2,986	2,487	421	6,711	470	127	26,938	9,321	1,990	46	165	57	453	.232	.313	.391	.705
10	Mets	385	330	.538	715	23,814	3,203	5,856	1,113	94	853	3,067	2,288	448	5,839	395	93	26,801	9,716	2,060	86	165	86	513	.246	.322	.408	.730
11	Blue Jays	383	332	.536	715	24,268	3,329	6,227	1,282	73	875	3,197	2,278	275	5,452	356	115	27,036	10,280	2,230	50	165	71	554	.257	.325	.424	.749
12	Padres	381	333	.534	714	23,980	3,223	5,942	1,175	81	785	3,077	2,477	256	5,506	468	134	27,019	9,634	2,041	120	186	106	524	.248	.323	.402	.724
13	Guardians	374	339	.525	713	23,863	3,039	5,820	1,150	106	706	2,880	2,051	312	5,382	580	141	26,506	9,300	1,962	81	199	134	479	.244	.310	.390	.699
14	Cardinals	373	342	.522	715	24,142	3,183	6,016	1,192	80	831	3,052	2,278	324	5,728	414	118	27,020	9,861	2,103	83	193	80	474	.249	.320	.408	.728
15	Red Sox	362	355	.505	717	24,584	3,428	6,316	1,465	93	834	3,272	2,210	300	6,343	408	125	27,320	10,469	2,392	45	181	104	494	.257	.324	.426	.749
16	Twins	355	359	.497	714	24,106	3,225	5,895	1,218	89	890	3,073	2,307	367	6,258	276	85	27,002	9,961	2,197	40	182	60	533	.245	.318	.413	.731
17	Orioles	353	360	.495	713	24,076	3,175	5,880	1,206	110	855	3,042	2,112	286	6,146	408	116	26,716	9,871	2,171	55	187	54	436	.244	.310	.410	.720
18	Cubs	352	363	.492	715	24,011	3,291	5,868	1,135	131	829	3,140	2,370	340	6,327	564	153	26,999	9,752	2,095	97	181	71	477	.244	.319	.406	.725
19	Tigers	351	365	.490	716	23,979	2,927	5,685	1,065	153	693	2,812	2,073	230	6,465	320	102	26,513	9,135	1,911	48	183	44	458	.237	.302	.381	.683
20	Reds	339	377	.473	716	23,907	3,225	5,778	1,169	104	823	3,081	2,295	397	6,415	550	171	26,854	9,624	2,096	90	165	50	483	.242	.316	.403	.719
21	Diamondbacks	332	383	.464	715	24,070	3,354	5,917	1,240	150	790	3,187	2,427	286	5,830	484	116	27,146	9,827	2,180	144	219	75	478	.246	.320	.408	.728
22	Rangers	328	387	.459	715	24,128	3,133	5,823	1,076	83	842	2,996	2,150	235	6,074	470	130	26,721	9,591	2,001	45	163	63	427	.241	.308	.398	.705
23	Angels	318	396	.445	714	23,898	2,999	5,665	1,051	102	871	2,864	2,080	308	6,510	392	146	26,514	9,533	2,024	81	147	101	473	.237	.305	.399	.704
24	Royals	315	400	.441	715	23,972	2,965	5,915	1,130	157	679	2,847	1,879	248	5,563	578	168	26,432	9,396	1,966	103	230	59	427	.247	.305	.392	.697
25	Marlins	307	406	.431	713	23,979	2,774	5,804	1,084	97	674	2,644	1,913	256	6,209	492	145	26,401	9,104	1,855	93	160	75	532	.242	.303	.380	.683