Cecil Cooper and Don Hoak are tied for the most strikeouts in a game when batting 1st, with 6 strikeouts.
Interpreted as:
What is the most strikeouts in a regular-season game for a leadoff hitter?| NAME | SO | DATE | TM | OPP | BAT ORDER | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Cooper | 6 | 6/14/1974 |  BOS | @ |  CAL | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | | D. Hoak | 6 | 5/2/1956 |  CHC | vs |  NYG | 1 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 9 | 1 | 0 | 1 | 0 | 0 | 0 |
| 3 |  | J. Altuve | 5 | 4/3/2025 |  HOU | @ |  MIN | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 |  | J. Chourio | 5 | 3/27/2025 |  MIL | @ |  NYY | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | | J. Bauers | 5 | 8/13/2023 | NYY | @ |  MIA | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | | L. Wade Jr. | 5 | 5/26/2023 |  SFG | @ | MIL | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | | R. UrÃas | 5 | 4/1/2023 |  BAL | @ |  BOS | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | D. Fowler | 5 | 9/24/2019 |  STL | @ |  ARI | 1 | 8 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 9 | 4 | 1 | 0 | 0 | 0 | 0 |
| 9 | | D. Fowler | 5 | 7/9/2018 |  OAK | @ | HOU | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 |  | T. Turner | 5 | 6/2/2018 |  WSH | @ |  ATL | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 |  | B. Dozier | 5 | 7/30/2017 | MIN | @ | OAK | 1 | 6 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 6 | 4 | 1 | 0 | 0 | 0 | 0 |
| 12 |  | T. Anderson | 5 | 8/10/2016 |  CWS | @ |  KCR | 1 | 6 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 7 | 1 | 0 | 0 | 0 | 0 | 0 |
| 13 | | M. A. Taylor | 5 | 6/22/2016 | WSH | @ |  LAD | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 |  | S. Choo | 5 | 4/12/2014 |  TEX | vs | HOU | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15 |  | S. Marte | 5 | 4/18/2013 |  PIT | vs | ATL | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | | R. Durham | 5 | 6/5/1998 | CWS | @ |  CHC | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17 | | R. Thompson | 5 | 9/29/1993 |  NYM | vs | STL | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | | D. DeShields | 5 | 9/17/1991 |  MON | @ | NYM | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19 | | B. Williams | 5 | 8/21/1991 | NYY | @ | KCR | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 |  | S. Sosa | 5 | 5/4/1990 |  CWS | @ | KCR | 1 | 6 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 0 | 0 | 0 | 0 |
| 21 | | P. Bradley | 5 | 9/7/1989 | BAL | @ |  TEX | 1 | 6 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 0 | 0 | 0 | 0 |
| 22 | | F. Taveras | 5 | 5/1/1979 | NYM | vs |  SDP | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23 | | P. Mangual | 5 | 8/11/1975 | MON | vs | SFG | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | D. Buford | 5 | 8/26/1971 | BAL | vs | CWS | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 |  | P. Rose | 5 | 8/15/1970 |  CIN | vs |  PHI | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1916 season.
Some of the information used here was obtained free of charge from Retrosheet.
Blue Jays 
Rays 
COL 
Tigers 
Mariners 
Padres 
