what mlb pitcher has the highest strikeout rate in a single season with at least 20 starts

Matt Kilroy has struck out the most hitters with 20+ starts in a season, with 513 strikeouts in his rookie season in 1886.

	NAME	SO	GS	SEASON	TM	G	W	L	W%	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Matt Kilroy M. Kilroy	513	68	1886	BAL	68	29	34	.460	3.37	66	5	0	583.0	476	218	350	10	182	19	0		2,469	61	7.92	2.81	2.82	0.15	20.8	7.4	1.13	.267	5.40	100	2.60	77	7.35	47
2	Toad Ramsey T. Ramsey	499	67	1886	LOU	67	38	27	.585	2.45	66	3	0	588.2	447	160	297	3	207	12	0		2,477	35	7.63	3.16	2.41	0.05	20.1	8.4	1.11	.253	4.54	71	2.59	76	6.83	54.7
3	Hugh Daily H. Daily	483	58	1884	TOT	58	28	28	.500	2.43	56	5	0	500.2	446	135	268	11	72		0		2,076	50	8.68	1.29	6.71	0.20	23.3	3.5	1.03		4.82	81	2.06	79	8.02	27.4
4	Dupee Shaw D. Shaw	451	66	1884	TOT	67	30	33	.476	2.30	60	5	0	543.1	446	139	281	9	109		1		2,244	24	7.47	1.81	4.14	0.15	20.1	4.9	1.02		4.65	77	2.43	81	7.39	29
5	Old Hoss Radbourn O. Hoss Radbourn	441	73	1884	PRO	75	59	12	.831	1.38	73	11	2	678.2	528	104	216	18	98		2		2,672	34	5.85	1.30	4.50	0.24	16.5	3.7	0.92		2.86	48	2.75	84	7.00	31.9
6	Charlie Buffinton C. Buffinton	417	67	1884	BSN	67	48	16	.750	2.15	63	8	0	587.0	506	140	225	15	76		0		2,383	24	6.39	1.17	5.49	0.23	17.5	3.2	0.99		3.45	74	2.57	77	7.76	46.8
7	Guy Hecker G. Hecker	385	73	1884	LOU	75	52	20	.722	1.80	72	6	0	670.2	526	134	230	4	56	16	2		2,649	27	5.17	0.75	6.88	0.05	14.5	2.1	0.87	.239	3.09	57	2.53	80	7.06	43
8	Nolan Ryan N. Ryan	383	39	1973	CAL	41	21	16	.568	2.87	26	4	1	326.0	238	104	113	18	162	7	2	2	1,355	15	10.57	4.47	2.36	0.50	28.3	12.0	1.23	.280	3.12	80	2.48	69	6.57	40.9
9	Sandy Koufax S. Koufax	382	41	1965	LAD	43	26	8	.765	2.04	27	8	2	335.2	216	76	90	26	71	5	2	4	1,297	11	10.24	1.90	5.38	0.70	29.5	5.5	0.86	.234	2.41	63	1.93	61	5.79	47.9
10	Bill Sweeney B. Sweeney	374	60	1884	BLU	62	40	21	.656	2.59	58	4	0	538.0	522	155	294	13	74		2		2,270	43	6.26	1.24	5.05	0.22	16.5	3.3	1.11		4.92	80	2.61	93	8.73	19.5
11	Randy Johnson R. Johnson	372	34	2001	ARI	35	21	6	.778	2.49	3	2	0	249.2	181	69	74	19	71	18	1	2	994	8	13.41	2.56	5.24	0.68	37.4	7.1	1.01	.315	2.67	55	2.12	48	6.52	63.9
12	Pud Galvin P. Galvin	369	72	1884	BUF	72	46	22	.676	1.99	71	12	0	636.1	566	141	254	23	63		0		2,554	16	5.22	0.89	5.86	0.33	14.4	2.5	0.99		3.59	64	2.88	82	8.01	50.9
13	Mark Baldwin M. Baldwin	368	59	1889	COL	63	27	34	.443	3.61	54	6	1	513.2	458	206	358	9	274	20	4		2,275	83	6.45	4.80	1.34	0.16	16.2	12.0	1.43	.280	6.27	100	3.52	98	8.02	-3
14	Nolan Ryan N. Ryan	367	41	1974	CAL	42	22	16	.579	2.89	26	3	0	332.2	221	107	127	18	202	9	1	3	1,392	9	9.93	5.46	1.82	0.49	26.4	14.5	1.27	.255	3.44	85	2.97	84	5.98	20.2
15	Randy Johnson R. Johnson	364	35	1999	ARI	35	17	9	.654	2.48	12	2	0	271.2	207	75	86	30	70	9	0	3	1,079	4	12.06	2.32	5.20	0.99	33.7	6.5	1.02	.292	2.85	53	2.75	59	6.86	57.2
16	Tim Keefe T. Keefe	359	68	1883	NYM	68	41	27	.603	2.41	68	5	0	619.0	488	166	244	6	108		0		2,517	27	5.22	1.57	3.32	0.09	14.3	4.3	0.96		3.55	72	2.74	82	7.10	45.1
17	Toad Ramsey T. Ramsey	355	64	1887	LOU	65	37	27	.578	3.43	61	0	0	561.0	544	214	358	9	167	16	1		2,430	46	5.70	2.68	2.13	0.14	14.6	6.9	1.27	.284	5.74	78	3.20	76	8.73	64.2
18	Rube Waddell R. Waddell	349	46	1904	PHA	46	25	19	.568	1.62	39	8	0	383.0	307	69	109	5	91	14	0		1,496	8	8.20	2.14	3.84	0.12	23.3	6.1	1.04	.291	2.56	61	1.59	62	7.21	41.5
19	Bob Feller B. Feller	348	42	1946	CLE	48	26	15	.634	2.18	36	10	4	371.1	277	90	101	11	153	3	5		1,512	3	8.43	3.71	2.27	0.27	23.0	10.1	1.16	.267	2.45	65	2.16	65	6.71	48.3
20	Randy Johnson R. Johnson	347	35	2000	ARI	35	19	7	.731	2.64	8	3	0	248.2	202	73	89	23	76	6	0	1	1,001	5	12.56	2.75	4.57	0.83	34.7	7.6	1.12	.326	3.22	56	2.53	53	7.31	61.1
21	Hardie Henderson H. Henderson	346	52	1884	BLA	52	27	23	.540	2.62	50	4	0	439.1	382	128	235	9	116	16	0		1,900	45	7.09	2.38	2.98	0.18	18.2	6.1	1.13	.264	4.81	81	2.87	89	7.83	16.5
22	Mickey Welch M. Welch	345	65	1884	NYG	65	39	21	.650	2.50	62	4	0	557.1	528	155	275	12	146		1		2,370	39	5.57	2.36	2.36	0.19	14.6	6.2	1.21		4.44	85	3.10	92	8.53	14.6
23	Jim Whitney J. Whitney	345	56	1883	BSN	62	37	21	.638	2.24	54	1	2	514.0	492	128	258	7	35		5		2,101	37	6.04	0.61	9.86	0.12	16.4	1.7	1.03		4.52	74	2.29	75	8.61	39.8
24	Jim McCormick J. McCormick	343	65	1884	TOT	66	40	25	.615	2.37	63	10	0	569.0	508	150	263	19	89		2		2,336	15	5.43	1.41	3.85	0.30	14.7	3.8	1.05		4.16	80	2.97	94	8.04	9.6
25	Nolan Ryan N. Ryan	341	37	1977	CAL	37	19	16	.543	2.77	22	4	0	299.0	198	92	110	12	204	9	0	7	1,272	21	10.26	6.14	1.67	0.36	26.8	16.0	1.34	.263	3.31	72	3.11	79	5.96	27.9