Chris Sale has the best career K/9, with 11.08 per nine innings.

which pitcher has the highest career strikeouts per nine innings
Interpreted as:
Which pitcher has the highest career strikeouts per nine innings with a minimum of 1500 IP?
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SaleScherzerJohnsonMartinezKershawRyanLincecumKoufaxVerlanderLynnLirianoMcDowellSantanaNomoPriceGonzalezBumgarnerSchillingKazmirClemensHamelsFernandez11.0810.7310.6110.049.819.559.299.289.089.049.018.868.838.738.738.668.608.608.568.558.548.40
NAMEGK/9IPWLW%GSCGGFSHOSVHTBFRERHRBBIBBHBPSOWPERAWHIPH/9BB/9K/BBERA-FIPFIP-PRAA
Chris SaleChris Sale32111.081672.111474.60624116253121,3576,727609563178386151022,059383.031.047.302.085.33712.9269238.3
Max ScherzerMax Scherzer41110.732561.219397.666402122502,08310,36096489528868520973,053733.141.087.322.414.46753.1175292.6
Randy JohnsonRandy Johnson61810.614135.1303166.64660310073723,34617,0671,7031,5134111,497371904,8751093.291.177.283.263.26753.1873554.3
Pedro MartinezPedro Martinez47610.042827.1219100.68740946231732,22111,3941,006919239760301413,154622.931.057.072.424.15662.9168454.6
Clayton KershawClayton Kershaw3829.812471.218884.6913792511501,8699,72874668419860627382,693952.491.006.812.214.44642.7669337.1
Nolan RyanNolan Ryan8079.555386.0324292.526773222136133,92322,5752,1781,9113212,795781585,7142773.191.256.564.672.04902.9683370.2
Tim LincecumTim Lincecum2789.291682.011089.553270103711,5067,12074669914766933441,7361073.741.298.063.582.59993.449081.5
Sandy KoufaxSandy Koufax3979.282324.116587.655314137444091,7549,49780671320481748182,396872.761.116.793.162.93752.6975226.6
Justin VerlanderJustin Verlander4589.083014.0228130.637458260902,55212,3081,1971,11031385527993,041873.311.137.622.553.56783.4080283.3
Lance LynnLance Lynn2889.041583.211577.59926444211,4356,68966061315257420661,591513.481.278.163.262.77853.588889.2
Francisco LirianoFrancisco Liriano4199.011813.2112114.496300319111,6497,78191183718481615621,8151004.151.368.184.052.221013.889538.5
Sam McDowellSam McDowell4258.862492.1141134.5133461033923141,94810,5879998791641,31274592,4531403.171.317.034.741.87903.0684160.4
Johan SantanaJohan Santana3608.832025.213978.64128415231011,7268,26277372122056713361,988683.201.137.672.523.51743.4381187.6
Hideo NomoHideo Nomo3238.731976.1123109.530318162901,7688,46299393225190831381,9181094.241.358.054.132.111024.229814.5
David PriceDavid Price3658.732108.015582.654322177311,8968,65985578021655414632,044403.331.168.092.373.69813.3883164
Gio GonzalezGio Gonzalez3448.661933.0131101.56532844201,7448,24285779517181521501,860593.701.328.123.792.28913.689177.1
Madison BumgarnerMadison Bumgarner3288.602052.0127107.543325161701,8158,38582175023049038791,961273.291.127.962.154.00853.509175
Curt SchillingCurt Schilling5698.603261.0216146.597436838120222,99813,2841,3181,25334771143523,116723.461.148.271.964.38803.2276373.6
Scott KazmirScott Kazmir3038.561701.010897.52730130101,6117,30883076019368717681,618744.021.358.523.632.36984.029726.3
Roger ClemensRoger Clemens7098.554916.2354184.65870711804604,18520,2401,8851,7073631,580631594,6721433.121.177.662.892.96703.0871680.4
Cole HamelsCole Hamels4238.542698.0163122.572422170702,42411,1151,1031,027310767431002,560573.431.188.092.563.34823.6888151.6
Sid FernandezSid Fernandez3078.401866.211496.543300252911,4217,66874969619171533411,743223.361.146.853.452.44903.519350.9
Ian KennedyIan Kennedy4328.371845.2102107.4882902971561,7427,83090684326662327811,716784.111.288.493.042.751014.27107-58.6
J.R. RichardJ.R. Richard2388.371606.010771.6012217631901,2276,6746255627377015171,493923.151.246.884.321.94922.8582114.7
Jake PeavyJake Peavy3888.362377.0152126.547377153602,1349,8381,01196025970842782,207463.631.208.082.683.12903.6489127.6