Since 2001, Albert Pujols has hit the most home runs, with 703 homers.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Albert Pujols A. Pujols	703	3,080	11,421	1,914	3,384	686	16	2,218	1,373	123	1,404	117	43	13,041	6,211	1,405	1	123	316	426	.296	.374	.544	.918	2233	685	.385	141	673
2	David Ortiz D. Ortiz	521	2,167	7,878	1,302	2,262	573	18	1,653	1,216	33	1,566	15	9	9,211	4,434	1,112	2	82	204	212	.287	.381	.563	.944	1638	550.4	.396	143	481.6
3	Miguel Cabrera M. Cabrera	511	2,797	10,356	1,551	3,174	627	17	1,881	1,258	74	2,105	40	21	11,796	5,368	1,155	5	103	238	364	.306	.382	.518	.901	1981	585.3	.382	139	547.8
4	Alex Rodriguez A. Rodriguez	507	1,994	7,440	1,394	2,149	354	18	1,491	1,028	145	1,671	196	40	8,692	4,060	879	0	79	88	198	.289	.382	.546	.928	1543	501.9	.394	142	455
5	Nelson Cruz N. Cruz	464	2,055	7,501	1,090	2,053	372	15	1,325	738	86	1,916	84	32	8,387	3,847	851	2	60	78	179	.274	.343	.513	.856	1294	313.6	.363	129	286.2
6	Adam Dunn A. Dunn	462	2,001	6,883	1,097	1,631	334	10	1,168	1,317	86	2,379	63	25	8,328	3,371	806	2	40	122	100	.237	.364	.490	.854	1285	297.9	.367	123	240
7	Adrian Beltre A. Beltre	435	2,566	9,825	1,351	2,828	570	31	1,533	717	86	1,510	88	29	10,727	4,765	1,036	5	94	98	258	.288	.339	.485	.824	1522	254.9	.352	117	209.4
8	Giancarlo Stanton G. Stanton	429	1,649	6,025	907	1,551	305	11	1,103	776	53	1,963	42	15	6,893	3,165	745	0	39	88	153	.257	.345	.525	.871	1093	294.9	.368	135	288.9
9	Edwin Encarnacion E. Encarnacion	424	1,960	7,040	1,099	1,832	370	10	1,261	903	105	1,426	61	14	8,114	3,494	804	0	66	54	185	.260	.350	.496	.846	1233	280.2	.362	125	235.4
10	Mark Teixeira M. Teixeira	409	1,862	6,936	1,099	1,862	408	18	1,298	918	111	1,441	26	7	8,029	3,533	835	0	64	91	158	.268	.360	.509	.869	1268	317.6	.371	127	262.4
11	Alfonso Soriano A. Soriano	409	1,944	7,692	1,145	2,085	478	31	1,155	495	86	1,785	287	83	8,334	3,852	918	7	54	68	123	.271	.320	.501	.821	1161	167.3	.349	111	118.3
12	Carlos Beltran C. Beltran	406	2,318	8,675	1,409	2,423	518	64	1,428	1,000	46	1,591	269	41	9,832	4,287	988	16	95	100	172	.279	.353	.494	.848	1479	311.9	.362	123	272.4
13	Mike Trout M. Trout	387	1,547	5,616	1,137	1,667	312	55	972	992	101	1,520	214	38	6,766	3,250	754	0	57	122	69	.297	.408	.579	.987	1327	541.3	.413	168	543.9
14	Paul Konerko P. Konerko	387	1,983	7,132	986	1,985	344	3	1,205	812	89	1,209	7	3	8,108	3,496	734	0	75	80	230	.278	.356	.490	.846	1223	257.6	.363	120	203.2
15	Ryan Howard R. Howard	382	1,572	5,707	848	1,475	277	21	1,194	709	59	1,843	12	5	6,530	2,940	680	0	55	154	116	.258	.343	.515	.859	976	212.1	.361	121	175.3
16	Jim Thome J. Thome	379	1,469	4,788	868	1,295	237	9	1,014	983	36	1,495	2	9	5,847	2,687	625	0	40	119	93	.270	.396	.561	.957	1077	368.3	.403	146	337.1
17	Aramis Ramirez A. Ramirez	374	2,031	7,575	1,054	2,169	469	20	1,351	599	118	1,121	29	17	8,373	3,800	863	0	81	58	221	.286	.345	.502	.846	1256	263.9	.362	119	197.9
18	Paul Goldschmidt P. Goldschmidt	365	1,961	7,245	1,222	2,100	454	23	1,203	1,059	50	1,904	170	35	8,410	3,695	842	0	56	117	169	.290	.382	.510	.892	1421	436.5	.379	139	392.6
19	Joey Votto J. Votto	356	2,056	7,252	1,171	2,135	459	22	1,144	1,365	81	1,640	80	29	8,746	3,706	837	0	48	147	168	.294	.409	.511	.920	1563	539.6	.394	145	472.9
20	Ryan Braun R. Braun	352	1,766	6,622	1,080	1,963	408	49	1,154	586	77	1,363	216	60	7,329	3,525	809	0	44	56	179	.296	.358	.532	.891	1210	352.7	.379	135	310.8
21	Freddie Freeman F. Freeman	349	2,054	7,635	1,313	2,293	515	31	1,253	1,021	108	1,649	98	31	8,826	3,917	895	0	62	136	161	.300	.388	.513	.901	1518	487.8	.383	142	454.5
22	Manny Machado M. Machado	345	1,767	6,927	1,011	1,933	373	18	1,063	620	27	1,324	105	39	7,648	3,377	736	14	60	69	212	.279	.338	.488	.825	1116	217.8	.350	123	208.8
23	Nolan Arenado N. Arenado	344	1,710	6,520	957	1,853	396	33	1,145	563	41	1,055	29	23	7,205	3,347	773	5	76	79	195	.284	.341	.513	.855	1109	261.6	.359	118	156.5
24	Jose Bautista J. Bautista	344	1,798	6,051	1,022	1,496	312	17	975	1,032	80	1,394	70	32	7,244	2,874	673	23	58	58	170	.247	.361	.475	.836	1085	241.2	.362	126	211.3
25	Curtis Granderson C. Granderson	344	2,057	7,236	1,217	1,800	346	95	937	924	67	1,916	153	50	8,306	3,368	785	30	49	31	64	.249	.337	.465	.803	1149	173.1	.347	115	147.8