The New York Yankees put up their most runs in a game versus the Red Sox on September 28, 1923, with 24 runs.

Interpreted as:

yankees most runs in a regular-season game scored vs red sox

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	24	9/28/1923	NYY	@	BSA	W 24-4	55	30	8	0	2	21	6	0	7	2	0	62	44	10	1				.545	.590	.800	1.390
2	Yankees	22	6/19/2000	NYY	@	BOS	W 22-1	47	19	4	1	5	21	7	0	4	1	0	55	40	10	0	1	1	0	.404	.473	.851	1.324
3	Yankees	20	8/21/2009	NYY	@	BOS	W 20-11	49	23	8	1	2	20	5	0	5	0	0	54	39	11	0	0	0	1	.469	.519	.796	1.314
4	Yankees	19	9/26/2008	NYY	@	BOS	W 19-8	44	20	7	0	3	18	5	2	5	1	0	54	36	10	0	3	0	1	.455	.500	.818	1.318
5	Yankees	19	8/13/1940	NYY	vs	BSA	W 19-8	34	15	2	1	3	18	4	1	1	2	0	41	28	6	2			0	.441	.513	.824	1.336
6	Yankees	18	5/10/1952	NYY	vs	BSA	W 18-3	41	19	1	0	2	16	9	2	6	1	0	52	26	3	0		0	2	.463	.577	.634	1.211
7	Yankees	17	6/29/2019	NYY	@	BOS	W 17-13	45	19	7	0	3	17	6	0	11	0	0	51	35	10	0	0	0	1	.422	.490	.778	1.268
8	Yankees	17	5/27/1957	NYY	@	BOS	W 17-8	38	13	7	0	1	14	11	0	6	0	0	53	23	8	2	2	1	0	.342	.471	.605	1.076
9	Yankees	17	7/7/1954	NYY	vs	BOS	W 17-9	37	18	0	4	3	16	3	0	3	0	0	42	35	7	2	0	0	0	.486	.525	.946	1.471
10	Yankees	17	5/25/1947	NYY	vs	BSA	W 17-2	41	17	4	1	2	15	13	0	8	0	0	54	29	7	0			0	.415	.556	.707	1.263
11	Yankees	17	5/30/1939	NYY	@	BSA	W 17-9	42	17	6	0	0	17	8	2	2	2	0	54	23	6	2			0	.405	.519	.548	1.067
12	Yankees	16	7/2/1965	NYY	@	BOS	W 16-2	48	21	2	1	2	16	2	0	8	0	0	51	31	5	0	1	0	0	.438	.451	.646	1.097
13	Yankees	16	4/18/1959	NYY	@	BOS	W 16-7	44	18	3	1	3	16	5	1	8	1	0	50	32	7	0	0	1	1	.409	.480	.727	1.207
14	Yankees	16	4/19/1950	NYY	@	BSA	W 16-7	36	15	3	0	1	16	13	0	5	0	0	50	21	4	1		2	0	.417	.571	.583	1.155
15	Yankees	16	9/23/1933	NYY	@	BSA	W 16-12	43	23	7	1	2	15	4	1	3	2	3	50	38	10	2				.535	.583	.884	1.467
16	Yankees	15	4/21/2012	NYY	@	BOS	W 15-9	42	16	4	0	3	15	8	0	9	1	0	50	29	7	0	0	2	1	.381	.480	.690	1.170
17	Yankees	15	4/16/2008	NYY	vs	BOS	W 15-9	39	16	5	0	2	13	5	1	4	1	0	45	27	7	0	0	1	0	.410	.489	.692	1.181
18	Yankees	15	9/7/1978	NYY	@	BOS	W 15-3	47	21	4	1	0	15	4	1	8	0	0	54	27	5	1	1	0	0	.447	.491	.574	1.065
19	Yankees	15	6/3/1966	NYY	@	BOS	W 15-5	42	17	4	3	2	15	5	0	6	0	0	47	33	9	0	0	3	1	.405	.468	.786	1.254
20	Yankees	15	7/2/1950	NYY	@	BSA	W 15-9	39	13	2	0	3	12	9	0	3	0	0	49	24	5	1		0	2	.333	.458	.615	1.074
21	Yankees	15	4/18/1950	NYY	@	BSA	W 15-10	41	15	4	3	0	14	8	1	5	0	0	51	25	7	1		0	0	.366	.480	.610	1.090
22	Yankees	15	7/5/1937	NYY	vs	BSA	W 15-0	39	16	2	1	2	14	7	0	3	0	0	46	26	5	0				.410	.500	.667	1.167
23	Yankees	15	6/6/1934	NYY	@	BSA	W 15-3	52	25	3	1	1	14	5	0	3	0	0	57	33	5	0				.481	.526	.635	1.161
24	Yankees	15	6/30/1932	NYY	@	BSA	W 15-4	41	14	4	0	1	12	11	0	3	3	0	52	21	5	0				.341	.481	.512	.993
25	Yankees	15	5/26/1929	NYY	@	BSA	W 15-4	43	16	6	1	3	15	5	1	3	1	0	49	33	10	0				.372	.449	.767	1.216