Jesse Crain has the lowest career ERA in starts when pitching at least 500 innings with at most 5 saves, with an ERA of 3.05.
| NAME | ERA | IP | GS | SV | SEASON | TM | G | W | L | W% | SO | CG | SHO | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Crain | 2.00 | 27.0 | 0 | 0 | 2004 |  MIN | 22 | 3 | 0 | 1.000 | 14 | 0 | 0 | 17 | 6 | 6 | 2 | 12 | 1 | 3 | 1 | 109 | 1 | 4.67 | 4.00 | 1.17 | 0.67 | 12.8 | 11.0 | 1.07 | .188 | 2.00 | 43 | 4.41 | 101 | 5.67 | -0.1 |
| 2 | | J. Crain | 2.71 | 79.2 | 0 | 1 | 2005 | MIN | 75 | 12 | 5 | .706 | 25 | 0 | 0 | 61 | 24 | 28 | 6 | 29 | 5 | 17 | 7 | 326 | 2 | 2.82 | 3.28 | 0.86 | 0.68 | 7.7 | 8.9 | 1.13 | .211 | 3.16 | 63 | 4.64 | 111 | 6.89 | -4.2 |
| 3 | | J. Crain | 3.52 | 76.2 | 0 | 1 | 2006 | MIN | 68 | 4 | 5 | .444 | 60 | 0 | 0 | 79 | 30 | 31 | 6 | 18 | 2 | 24 | 2 | 325 | 1 | 7.04 | 2.11 | 3.33 | 0.70 | 18.5 | 5.5 | 1.27 | .305 | 3.64 | 79 | 3.37 | 77 | 9.27 | 8.7 |
| 4 | | J. Crain | 5.51 | 16.1 | 0 | 0 | 2007 | MIN | 18 | 1 | 2 | .333 | 10 | 0 | 0 | 19 | 10 | 16 | 4 | 4 | 1 | 5 | 0 | 71 | 0 | 5.51 | 2.20 | 2.50 | 2.20 | 14.1 | 5.6 | 1.41 | .288 | 8.82 | 125 | 6.11 | 142 | 10.47 | -3.4 |
| 5 | | J. Crain | 3.59 | 62.2 | 0 | 0 | 2008 | MIN | 66 | 5 | 4 | .556 | 50 | 0 | 0 | 62 | 25 | 29 | 6 | 24 | 1 | 14 | 3 | 268 | 2 | 7.18 | 3.45 | 2.08 | 0.86 | 18.7 | 9.0 | 1.37 | .299 | 4.16 | 84 | 3.97 | 95 | 8.90 | 1.5 |
| 6 | | J. Crain | 4.70 | 51.2 | 0 | 0 | 2009 | MIN | 56 | 7 | 4 | .636 | 43 | 0 | 0 | 48 | 27 | 28 | 3 | 27 | 5 | 15 | 3 | 230 | 1 | 7.49 | 4.70 | 1.59 | 0.52 | 18.7 | 11.7 | 1.45 | .296 | 4.88 | 108 | 4.04 | 94 | 8.36 | 1.4 |
| 7 | | J. Crain | 3.04 | 68.0 | 0 | 1 | 2010 | MIN | 71 | 1 | 1 | .500 | 62 | 0 | 0 | 53 | 23 | 27 | 5 | 27 | 1 | 16 | 4 | 278 | 3 | 8.21 | 3.57 | 2.30 | 0.66 | 22.3 | 9.7 | 1.18 | .262 | 3.57 | 73 | 3.44 | 83 | 7.01 | 5.2 |
| 8 | | J. Crain | 2.62 | 65.1 | 0 | 1 | 2011 |  CWS | 67 | 8 | 3 | .727 | 70 | 0 | 0 | 50 | 19 | 20 | 7 | 31 | 0 | 11 | 5 | 268 | 0 | 9.64 | 4.27 | 2.26 | 0.96 | 26.1 | 11.6 | 1.24 | .269 | 2.76 | 62 | 3.69 | 87 | 6.89 | 3.9 |
| 9 | | J. Crain | 2.44 | 48.0 | 0 | 0 | 2012 | CWS | 51 | 2 | 3 | .400 | 60 | 0 | 0 | 29 | 13 | 14 | 5 | 23 | 1 | 6 | 1 | 194 | 4 | 11.25 | 4.31 | 2.61 | 0.94 | 30.9 | 11.9 | 1.08 | .229 | 2.63 | 57 | 3.44 | 80 | 5.44 | 4.4 |
| 10 | | J. Crain | 0.74 | 36.2 | 0 | 0 | 2013 | CWS | 38 | 2 | 3 | .400 | 46 | 0 | 0 | 31 | 3 | 6 | 0 | 11 | 1 | 5 | 1 | 152 | 0 | 11.29 | 2.70 | 4.18 | 0.00 | 30.3 | 7.2 | 1.15 | .330 | 1.47 | 18 | 1.52 | 37 | 7.61 | 10.2 |
| Total | 3.05 | 532.0 | 0 | 4 | 532 | 45 | 30 | .600 | 440 | 0 | 0 | 449 | 180 | 205 | 44 | 206 | 18 | 116 | 27 | 2,221 | 14 | 7.44 | 3.48 | 2.14 | 0.74 | 19.8 | 9.3 | 1.23 | .268 | 3.47 | 71 | 3.76 | 89 | 7.60 | 27.6 |
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