The Cleveland Guardians have a record of 49-39 on April 21 all-time.

	TEAM	DATE	REC	TM		OPP	RESULT	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Naps	4/21/1906	0-1	CLE	@	SLA	L 1-5	.000	35	1	8	1	0	0		2	0		1		37	9	1	0				.229	.270	.257	.527
2	Naps	4/21/1908	1-0	CLE	vs	CWS	W 5-1	1.000	31	5	8	2	1	0	4	0	1	5	5		33	12	3	1				.258	.281	.387	.668
3	Naps	4/21/1910	0-1	CLE	vs	DET	L 0-5	.000	31	0	5	2	0	0	0	2	1	0	0		34	7	2	0				.161	.235	.226	.461
4	Naps	4/21/1911	1-0	CLE	vs	SLA	W 6-5	1.000	27	6	9	0	0	1		7	0	4	2		37	12	1	3				.333	.471	.444	.915
5	Naps	4/21/1912	1-0	CLE	@	DET	W 4-0	1.000	33	4	8	3	0	0	4	1	2	1	0		38	11	3	2				.242	.306	.333	.639
6	Naps	4/21/1913	1-0	CLE	vs	SLA	W 8-3	1.000	36	8	15	5	2	0	8	2	1	1	2		40	24	7	1				.417	.462	.667	1.128
7	Naps	4/21/1914	0-1	CLE	@	DET	L 4-7	.000	31	4	9	2	0	0	4	6	0	4	3		39	11	2	2				.290	.405	.355	.760
8	Indians	4/21/1915	1-0	CLE	@	SLA	W 3-1	1.000	22	3	6	1	0	0		3	0	0	0		27	7	1	2				.273	.360	.318	.678
9	Indians	4/21/1916	0-1	CLE	@	SLA	L 1-11	.000	27	1	1	1	0	0		5	0	0	3		33	2	1	1				.037	.188	.074	.262
10	Indians	4/21/1917	0-1	CLE	vs	DET	L 4-5	.000	30	4	6	0	1	0	3	7	2	2	2		40	8	1	1				.200	.385	.267	.651
11	Indians	4/21/1918	0-1	CLE	vs	SLA	L 7-11	.000	33	7	11	3	0	0	6	10	1	4	1		44	14	3	0				.333	.500	.424	.924
12	Indians	4/21/1921	1-0	CLE	vs	SLA	W 4-3	1.000	32	4	11	7	0	0	4	2	0	2	0	0	37	18	7	3				.344	.382	.563	.945
13	Indians	4/21/1922	0-1	CLE	@	DET	L 7-15	.000	36	7	16	2	0	0	7	4	1	1	0	0	44	18	2	3				.444	.512	.500	1.012
14	Indians	4/21/1923	1-0	CLE	vs	CWS	W 5-1	1.000	31	5	11	1	0	0	5	2	0	1	1	2	35	12	1	2				.355	.394	.387	.781
15	Indians	4/21/1925	0-1	CLE	@	DET	L 3-4	.000	35	3	10	2	0	1	3	4	0	2	0	2	39	15	3	0				.286	.359	.429	.788
16	Indians	4/21/1926	1-0	CLE	vs	DET	W 12-2	1.000	37	12	16	7	0	0	10	6	0	1	0	0	46	23	7	3				.432	.512	.622	1.133
17	Indians	4/21/1930	1-0	CLE	@	DET	W 6-1	1.000	34	6	10	2	0	0	5	1	1	0	0	0	38	12	2	2				.294	.333	.353	.686
18	Indians	4/21/1931	1-0	CLE	vs	DET	W 5-4	1.000	30	5	8	2	1	0	5	5	0	1	1	0	38	12	3	3				.267	.371	.400	.771
19	Indians	4/21/1932	0-1	CLE	vs	DET	L 3-5	.000	32	3	7	2	0	0	3	5	0	5	0	0	37	9	2	0				.219	.324	.281	.606
20	Indians	4/21/1933	1-0	CLE	vs	DET	W 5-0	1.000	30	5	9	3	0	1	3	0	0	9	0	1	31	15	4	1				.300	.300	.500	.800
21	Indians	4/21/1935	0-1	CLE	@	DET	L 2-3	.000	46	2	10	1	0	1	2	3	0	5	1	1	49	14	2	0				.217	.265	.304	.570
22	Indians	4/21/1938	1-0	CLE	vs	SLA	W 4-3	1.000	34	4	11	4	0	0	4	5	0	5	0	0	39	15	4	0				.324	.410	.441	.851
23	Indians	4/21/1939	1-0	CLE	vs	DET	W 5-1	1.000	35	5	11	3	1	0	5	3	0	4	0	0	38	16	4	0			0	.314	.368	.457	.826
24	Indians	4/21/1940	0-1	CLE	vs	DET	L 2-12	.000	31	2	5	2	0	1	2	2	0	1	0	0	33	10	3	0			0	.161	.212	.323	.535
25	Indians	4/21/1942	1-0	CLE	vs	SLA	W 4-2	1.000	31	4	7	2	0	0	3	4	0	1	0	0	35	9	2	0			0	.226	.314	.290	.605
	Total		49-39					.557	2,935	415	780	155	15	79		334	30		58	22	3,379	1,202	249	61	19	10	44	.266	.345	.410	.754