Roel Ramirez had the highest ERA with 0.1+ innings pitched in 2021, with an ERA of 81.00 in his rookie season.

Interpreted as:

highest era by a player in 2021, min 0.3 ip

	NAME	ERA	IP	SEASON	TM	G	W	L	W%	GS	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Roel Ramirez R. Ramirez	81.00	0.1	2021	STL	1	0	0		0	0	0	0	0	1	3	3	0	2	0	0	0	4	0	0.00	54.00	0.00	0.00	0.0	50.0	9.00	.500	81.00	1990	21.16	509	27.00	-0.6
2	John Axford J. Axford	54.00	0.1	2021	MIL	1	0	0		0	0	0	0	0	2	2	2	0	1	1	0	0	5	0	0.00	27.00	0.00	0.00	0.0	20.0	9.00	.667	54.00	1287	21.16	494	54.00	-0.6
3	Felix Pena F. Pena	37.80	1.2	2021	LAA	2	0	0		0	2	0	0	0	7	7	7	0	4	0	0	0	16	1	10.80	21.60	0.50	0.00	12.5	25.0	6.60	.700	37.80	858	7.96	183	37.80	-0.7
4	Colten Brewer C. Brewer	36.00	1.0	2021	BOS	1	0	0		0	1	0	0	0	4	4	4	0	3	0	0	0	9	0	9.00	27.00	0.33	0.00	11.1	33.3	7.00	.800	36.00	786	10.16	235	36.00	-0.6
5	Wilmer Difo W. Difo	36.00	2.0	2021	PIT	2	0	0		0	1	0	0	0	9	8	8	1	3	0	2	0	18	0	4.50	13.50	0.33	4.50	5.6	16.7	6.00	.615	36.00	850	13.16	310	40.50	-2
6	Robel Garcia R. Garcia	36.00	1.0	2021	HOU	1	0	0		0	0	0	0	0	5	4	4	2	0	0	1	0	8	0	0.00	0.00		18.00	0.0	0.0	5.00	.500	36.00	842	29.16	689	45.00	-2.8
7	Jesús Tinoco J. Tinoco	33.75	1.1	2021	COL	1	0	0		0	0	0	0	0	5	5	5	3	1	1	0	0	10	0	0.00	6.75	0.00	20.25	0.0	10.0	4.50	.400	33.75	699	36.91	829	33.75	-4.6
8	Keury Mella K. Mella	32.40	1.2	2021	ARI	2	0	0		0	2	0	0	0	8	6	6	2	2	0	1	0	15	0	10.80	10.80	1.00	10.80	13.3	13.3	6.00	.667	32.40	772	19.96	485	43.20	-3
9	Jorge Guzman J. Guzman	32.40	1.2	2021	MIA	2	0	0		0	3	0	0	0	4	6	6	0	6	0	0	1	15	0	16.20	32.40	0.50	0.00	20.0	40.0	6.00	.667	32.40	772	10.36	249	21.60	-1.2
10	Justin Topa J. Topa	29.70	3.1	2021	MIL	4	0	0		0	1	0	0	0	12	11	11	2	1	0	0	1	23	0	2.70	2.70	1.00	5.40	4.3	4.3	3.90	.526	29.70	708	11.26	263	32.40	-2.6
11	Albert Almora Jr. A. Almora Jr.	27.00	1.0	2021	NYM	1	0	0		0	0	0	0	0	1	3	3	1	1	1	1	0	6	0	0.00	9.00	0.00	9.00	0.0	16.7	2.00	.000	27.00	677	22.16	528	9.00	-2
12	Tyler Beede T. Beede	27.00	1.0	2021	SFG	1	0	0		0	2	0	0	0	2	3	3	0	0	1	0	0	6	1	18.00	0.00		0.00	33.3	0.0	2.00	.667	27.00	670	2.16	53	18.00	0.2
13	Brandon Drury B. Drury	27.00	0.2	2021	NYM	1	0	0		0	0	0	0	0	3	2	2	1	1	1	0	0	7	0	0.00	13.50	0.00	13.50	0.0	14.3	6.00	.500	27.00	677	31.66	754	40.50	-2.1
14	Francisco Mejía F. Mejía	27.00	2.0	2021	TBR	2	0	0		0	0	0	0	0	6	6	6	1	0	2	2	0	14	0	0.00	0.00		4.50	0.0	0.0	3.00	.455	27.00	658	12.66	308	27.00	-2
15	David Peralta D. Peralta	27.00	1.0	2021	ARI	1	0	0		0	1	0	0	0	4	3	3	1	0	1	1	0	9	0	9.00	0.00		9.00	11.1	0.0	4.00	.500	27.00	644	17.16	417	36.00	-1.5
16	Kevin Quackenbush K. Quackenbush	27.00	0.1	2021	LAD	1	0	0		0	1	0	0	0	3	1	1	0	0	0	0	0	4	0	27.00	0.00		0.00	25.0	0.0	9.00	1.000	27.00	663	-2.84	-66	81.00	0.3
17	Chaz Roe C. Roe	27.00	0.2	2021	TBR	1	0	0		0	2	0	0	0	1	2	2	0	1	0	0	0	4	0	27.00	13.50	2.00	0.00	50.0	25.0	3.00	1.000	27.00	658	1.66	40	13.50	0.2
18	Elvis Peguero E. Peguero	27.00	2.1	2021	LAA	3	0	1	.000	0	0	0	0	0	7	7	7	0	3	1	0	0	17	0	0.00	11.57	0.00	0.00	0.0	17.6	4.29	.538	27.00	613	8.31	190	27.00	-1
19	Kutter Crawford K. Crawford	22.50	2.0	2021	BOS	1	0	1	.000	1	2	0	0	0	5	5	5	1	2	0	0	0	13	0	9.00	9.00	1.00	4.50	15.4	15.4	3.50	.500	22.50	491	10.66	247	22.50	-1.4
20	Gregory Santos G. Santos	22.50	2.0	2021	SFG	3	0	2	.000	0	3	0	0	0	5	5	6	3	2	0	1	0	13	0	13.50	9.00	1.50	13.50	23.1	15.4	3.50	.400	27.00	559	22.66	557	22.50	-4.3
21	Kyle Lobstein K. Lobstein	20.25	1.1	2021	WSH	3	0	0		0	1	0	0	0	3	3	3	1	1	0	1	0	8	0	6.75	6.75	1.00	6.75	12.5	12.5	3.00	.400	20.25	483	13.66	319	20.25	-1.4
22	Cooper Criswell C. Criswell	20.25	1.1	2021	LAA	1	0	1	.000	1	0	0	0	0	6	3	3	0	0	0	0	0	10	0	0.00	0.00		0.00	0.0	0.0	4.50	.600	20.25	460	3.16	72	40.50	0.2
23	Mickey Jannis M. Jannis	18.90	3.1	2021	BAL	1	0	0		0	1	0	0	0	8	7	7	3	4	0	0	0	21	0	2.70	10.80	0.25	8.10	4.8	19.0	3.60	.385	18.90	429	17.86	394	21.60	-4.6
24	Anthony Bemboom A. Bemboom	18.00	1.0	2021	LAA	1	0	0		0	0	0	0	0	3	2	2	1	0	0	1	0	7	0	0.00	0.00		9.00	0.0	0.0	3.00	.333	18.00	408	16.16	371	27.00	-1.3
25	Andy Burns A. Burns	18.00	1.0	2021	LAD	1	0	0		0	1	0	0	0	3	2	2	1	0	0	1	0	6	0	9.00	0.00		9.00	16.7	0.0	3.00	.500	18.00	442	14.16	331	27.00	-1.1