Babe Ruth has the highest OPS with >50 home runs in a season, with an OPS of 1.379 in 1920.

Interpreted as:

highest ops by a player in >50 home run season

	NAME	OPS	HR	SEASON	TM	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	WRC	WRAA	WOBA	WRC+	BRAA
1	Babe Ruth B. Ruth	1.379	54	1920	NYY	142	458	158	172	36	9	135	150	3	80	14	14	616	388	99	5				.376	.532	.847	191	120.9	.597	237	110.5
2	Barry Bonds B. Bonds	1.379	73	2001	SFG	153	476	129	156	32	2	137	177	9	93	13	3	664	411	107	0	2	35	5	.328	.515	.863	200	117.7	.537	234	116.6
3	Babe Ruth B. Ruth	1.359	59	1921	NYY	152	540	177	204	44	16	168	145	4	81	17	13	693	457	119	4				.378	.512	.846	214	127.8	.575	224	118.7
4	Babe Ruth B. Ruth	1.258	60	1927	NYY	151	540	158	192	29	8	165	137	0	89	7	6	691	417	97	14				.356	.486	.772	195	109.9	.545	212	104.8
5	Mark McGwire M. McGwire	1.222	70	1998	STL	155	509	130	152	21	0	147	162	6	155	1	0	681	383	91	0	4	28	8	.299	.470	.752	176	91.7	.492	205	90.7
6	Jimmie Foxx J. Foxx	1.218	58	1932	PHA	154	585	151	213	33	9	169	116	0	96	3	7	701	438	100	0				.364	.469	.749	193	105.6	.522	198	95.8
7	Mark McGwire M. McGwire	1.198	52	1996	OAK	130	423	104	132	21	0	113	116	8	112	0	0	548	309	73	0	1	16	14	.312	.467	.730	142	71.8	.489	190	68.5
8	Hack Wilson H. Wilson	1.177	56	1930	CHC	155	585	146	208	35	6	191	105	1	84	3		709	423	97	18				.356	.454	.723	189	89	.497	171	78.9
9	Sammy Sosa S. Sosa	1.174	64	2001	CHC	160	577	146	189	34	5	160	116	6	153	0	2	711	425	103	0	12	37	6	.328	.437	.737	171	82.7	.465	186	79.8
10	Babe Ruth B. Ruth	1.172	54	1928	NYY	154	536	163	173	29	8	146	137	3	87	4	5	684	380	91	8				.323	.463	.709	174	90.6	.510	201	89.3
11	Mickey Mantle M. Mantle	1.169	52	1956	NYY	150	533	132	188	22	5	130	112	2	99	10	1	652	376	79	1	4	6	4	.353	.464	.705	164	88.9	.498	202	84.6
12	Aaron Judge A. Judge	1.159	58	2024	NYY	158	559	122	180	36	1	144	133	9	171	10	0	703	392	95	0	2	20	22	.322	.458	.701	176	93.7	.476	219	95.5
13	Aaron Judge A. Judge	1.144	53	2025	NYY	152	541	137	179	30	2	114	124	7	160	12	5	679	372	85	0	7	36	16	.331	.457	.688	163	82.5	.463	203	82.7
14	Mickey Mantle M. Mantle	1.135	54	1961	NYY	153	514	131	163	16	6	128	126	0	112	12	1	646	353	76	1	5	9	2	.317	.448	.687	156	79.6	.478	197	78.8
15	Jim Thome J. Thome	1.122	52	2002	CLE	147	480	101	146	19	2	118	122	5	139	1	2	613	325	73	0	6	18	5	.304	.445	.677	142	68.3	.461	189	67.1
16	Hank Greenberg H. Greenberg	1.122	58	1938	DET	155	556	143	175	23	4	147	119	3	92	7	5	681	380	85	3				.315	.438	.683	166	80.3	.489	162	62
17	Mark McGwire M. McGwire	1.120	65	1999	STL	153	521	118	145	21	1	147	133	2	141	0	0	661	363	87	0	5	21	12	.278	.424	.697	150	64.2	.453	169	61.5
18	Luis Gonzalez L. Gonzalez	1.117	57	2001	ARI	162	609	128	198	36	7	142	100	14	83	1	1	728	419	100	0	5	24	14	.325	.429	.688	168	77.8	.454	173	69.4
19	Aaron Judge A. Judge	1.111	62	2022	NYY	157	570	133	177	28	0	131	111	6	175	16	3	692	391	90	0	5	19	14	.311	.425	.686	161	81.6	.458	208	84.5
20	Ralph Kiner R. Kiner	1.089	54	1949	PIT	152	549	116	170	19	5	127	117	1	61	6		667	361	78	0			10	.310	.432	.658	153	73.4	.484	179	65.8
21	Ryan Howard R. Howard	1.084	58	2006	PHI	159	581	104	182	25	1	149	108	9	181	0	0	704	383	84	0	6	37	7	.313	.425	.659	151	63	.436	162	57.5
22	Alex Rodriguez A. Rodriguez	1.067	54	2007	NYY	158	583	143	183	31	0	156	95	21	120	24	4	708	376	85	0	9	11	15	.314	.422	.645	155	67.5	.445	175	66.2
23	Willie Mays W. Mays	1.059	51	1955	NYG	152	580	123	185	18	13	127	79	4	60	24	4	670	382	82	0	7	13	12	.319	.400	.659	143	65.3	.450	171	59.7
24	Ralph Kiner R. Kiner	1.055	51	1947	PIT	152	565	118	177	23	4	127	98	2	81	1		666	361	78	1			12	.313	.417	.639	145	69.5	.472	169	58.2
25	Aaron Judge A. Judge	1.049	52	2017	NYY	155	542	128	154	24	3	114	127	5	208	9	4	678	340	79	0	4	11	15	.284	.422	.627	145	62.5	.430	174	61.5