Lou Gehrig has the highest career OPS + 150 in the postseason when making 150+ plate appearances, with 151.21.

Interpreted as:

highest postseason ops+ 150 by a player pas

	NAME	OPS+150	PA	OPS	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG
1	Lou Gehrig L. Gehrig	151.21	150	1.214	34	119	30	43	8	3	10	35	26	2	17	0	1	87	21	1		2	1	.361	.483	.731
2	Babe Ruth B. Ruth	151.21	167	1.214	41	129	37	42	5	2	15	33	33	2	30	4	3	96	22	2		2	3	.326	.470	.744
3	George Brett G. Brett	151.02	184	1.023	43	166	30	56	8	5	10	23	17	0	20	2	3	104	23	0	1	6	4	.337	.397	.627
4	Carlos Beltran C. Beltran	151.02	256	1.021	65	215	45	66	15	1	16	42	37	2	33	11	0	131	32	1	1	2	3	.307	.412	.609
5	Albert Pujols A. Pujols	150.99	360	.995	88	304	57	97	18	1	19	54	50	5	46	1	2	174	38	0	1	20	7	.319	.422	.572
6	Bryce Harper B. Harper	150.99	250	.986	57	208	42	57	14	1	17	34	38	2	56	8	1	124	32	1	1	4	5	.274	.390	.596
7	Nelson Cruz N. Cruz	150.98	207	.979	50	187	35	52	12	0	18	38	19	1	45	1	1	118	30	0	0	2	5	.278	.348	.631
8	Lance Berkman L. Berkman	150.95	224	.949	52	186	38	59	11	1	9	41	31	3	41	4	1	99	21	0	3	6	4	.317	.417	.532
9	David Ortiz D. Ortiz	150.95	369	.947	85	304	51	88	22	2	17	61	59	2	72	0	1	165	41	0	4	11	4	.289	.404	.543
10	Randy Arozarena R. Arozarena	150.95	184	.946	45	161	33	47	6	1	12	19	17	6	52	8	2	91	19	0	0	2	3	.292	.380	.565
11	Yordan Alvarez Y. Alvarez	150.94	252	.944	60	214	39	63	13	3	12	41	31	5	69	0	0	118	28	0	2	5	1	.294	.393	.551
12	Shohei Ohtani S. Ohtani	150.94	159	.940	33	129	27	32	4	1	11	24	29	1	45	1	3	71	16	0	0	9	0	.248	.390	.550
13	Manny Ramirez M. Ramirez	150.94	493	.937	111	410	67	117	19	0	29	78	72	5	91	1	1	223	48	0	6	12	17	.285	.394	.544
14	Barry Bonds B. Bonds	150.94	208	.936	48	151	33	37	8	2	9	24	52	1	26	9	1	76	19	0	4	21	1	.245	.433	.503
15	Hideki Matsui H. Matsui	150.93	235	.933	56	205	32	64	15	1	10	39	27	1	33	0	0	111	26	0	2	2	5	.312	.391	.541
16	J.D. Martinez	150.93	164	.930	41	137	16	39	5	0	10	34	24	1	42	0	1	74	15	0	2	3	2	.285	.390	.540
17	Juan Soto J. Soto	150.93	191	.927	43	160	31	45	8	0	11	30	27	2	40	2	1	86	19	1	1	4	1	.281	.389	.538
18	Giancarlo Stanton G. Stanton	150.93	202	.926	48	177	26	45	8	0	18	44	20	0	49	2	0	107	26	0	5	1	5	.254	.322	.605
19	Pablo Sandoval P. Sandoval	150.92	171	.921	42	157	21	53	13	0	6	20	10	3	24	0	0	84	19	0	1	3	7	.338	.386	.535
20	David Freese D. Freese	150.92	230	.919	69	204	26	61	17	2	10	36	20	4	55	0	1	112	29	0	2	2	9	.299	.370	.549
21	Fred McGriff F. McGriff	150.91	218	.912	50	188	36	57	10	1	10	37	27	0	40	1	1	99	21	0	3	4	4	.303	.385	.527
22	Jason Giambi J. Giambi	150.91	174	.911	45	138	19	40	6	0	7	19	30	4	30	1	0	67	13	0	2	2	3	.290	.425	.486
23	Steve Garvey S. Garvey	150.91	232	.910	55	222	32	75	8	3	11	31	8	0	32	2	2	122	22	2	0	4	4	.338	.361	.550
24	Mickey Mantle M. Mantle	150.91	273	.908	65	230	42	59	6	2	18	40	43	0	54	3	4	123	26	0	0	6	2	.257	.374	.535
25	Kyle Schwarber K. Schwarber	150.91	296	.907	73	244	44	57	7	0	23	37	46	4	79	5	0	133	30	0	2	5	4	.234	.361	.545