Between the 1920 and 1955 seasons, Spud Chandler had the best ERA in a season, with an ERA of 1.64 in 1943.
- Regular season
- Min. 1 Innings Pitched Per Team Game
| NAME | ERA | SEASON | TM | G | W | L | W% | GS | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | S. Chandler | 1.64 | 1943 | 30 | 20 | 4 | .833 | 30 | 134 | 20 | 5 | 0 | 253.0 | 197 | 46 | 62 | 5 | 54 | 4 | 0 | 989 | 3 | 4.77 | 1.92 | 2.48 | 0.18 | 13.5 | 5.5 | 0.99 | .242 | 2.21 | 50 | 2.30 | 68 | 7.01 | 29.8 | ||
| 2 | | C. Hubbell | 1.66 | 1933 | 45 | 23 | 12 | .657 | 33 | 156 | 22 | 10 | 5 | 308.2 | 256 | 57 | 69 | 6 | 47 | 3 | 11 | 1,206 | 3 | 4.55 | 1.37 | 3.32 | 0.17 | 12.9 | 3.9 | 0.98 | .252 | 2.01 | 52 | 2.53 | 74 | 7.46 | 31.1 | ||
| 3 | | M. Cooper | 1.78 | 1942 | 37 | 22 | 7 | .759 | 35 | 152 | 22 | 10 | 0 | 278.2 | 207 | 55 | 73 | 9 | 68 | 5 | 1 | 1,100 | 5 | 4.91 | 2.20 | 2.24 | 0.29 | 13.8 | 6.2 | 0.99 | .229 | 2.36 | 53 | 2.53 | 72 | 6.69 | 30.2 | ||
| 4 | | H. Newhouser | 1.81 | 1945 | 40 | 25 | 9 | .735 | 36 | 212 | 29 | 8 | 2 | 313.1 | 239 | 63 | 73 | 5 | 110 | 0 | 2 | 1,261 | 10 | 6.09 | 3.16 | 1.93 | 0.14 | 16.8 | 8.7 | 1.11 | .251 | 2.10 | 52 | 2.45 | 68 | 6.86 | 39.5 | ||
| 5 | | M. Lanier | 1.90 | 1943 | 32 | 15 | 7 | .682 | 25 | 123 | 14 | 2 | 3 | 213.1 | 195 | 45 | 62 | 3 | 75 | 2 | 5 | 882 | 0 | 5.19 | 3.16 | 1.64 | 0.13 | 13.9 | 8.5 | 1.27 | .283 | 2.62 | 56 | 2.53 | 76 | 8.23 | 19.4 | ||
| 6 | | G. Alexander | 1.91 | 1920 | 46 | 27 | 14 | .659 | 40 | 173 | 33 | 7 | 5 | 363.1 | 335 | 77 | 96 | 8 | 69 | 1 | 6 | 1,447 | 3 | 4.29 | 1.71 | 2.51 | 0.20 | 12.0 | 4.8 | 1.11 | .273 | 2.38 | 61 | 2.66 | 81 | 8.30 | 25 | ||
| 7 | | D. Luque | 1.93 | 1923 | 41 | 27 | 8 | .771 | 37 | 151 | 28 | 6 | 2 | 322.0 | 279 | 69 | 90 | 2 | 88 | 5 | 4 | 1,301 | 4 | 4.22 | 2.46 | 1.72 | 0.06 | 11.6 | 6.8 | 1.14 | .263 | 2.52 | 50 | 2.94 | 77 | 7.80 | 31 | ||
| 8 | | H. Newhouser | 1.94 | 1946 | 37 | 26 | 9 | .743 | 34 | 275 | 29 | 6 | 1 | 292.2 | 215 | 63 | 77 | 10 | 98 | 1 | 2 | 1,176 | 8 | 8.46 | 3.01 | 2.81 | 0.31 | 23.4 | 8.3 | 1.07 | .259 | 2.37 | 54 | 1.96 | 56 | 6.61 | 49.6 | ||
| 9 | | B. Pierce | 1.97 | 1955 | 33 | 15 | 10 | .600 | 26 | 157 | 16 | 6 | 3 | 205.2 | 162 | 45 | 50 | 16 | 64 | 3 | 5 | 5 | 836 | 4 | 6.87 | 2.80 | 2.45 | 0.70 | 18.8 | 7.7 | 1.10 | .245 | 2.19 | 50 | 2.83 | 72 | 7.09 | 24.5 | |
| 10 | | L. Warneke | 2.00 | 1933 | 36 | 18 | 13 | .581 | 34 | 133 | 26 | 4 | 1 | 287.1 | 262 | 64 | 83 | 8 | 75 | 3 | 1 | 1,175 | 6 | 4.17 | 2.35 | 1.77 | 0.25 | 11.3 | 6.4 | 1.17 | .266 | 2.60 | 62 | 3.05 | 88 | 8.21 | 12.8 | ||
| 11 | | A. Benton | 2.02 | 1945 | 31 | 13 | 8 | .619 | 27 | 76 | 12 | 5 | 3 | 191.2 | 175 | 43 | 68 | 7 | 63 | 2 | 4 | 811 | 3 | 3.57 | 2.96 | 1.21 | 0.33 | 9.4 | 7.8 | 1.24 | .253 | 3.19 | 58 | 3.24 | 90 | 8.22 | 7.9 | ||
| 12 | | L. Grove | 2.06 | 1931 | 41 | 31 | 4 | .886 | 30 | 175 | 27 | 4 | 5 | 288.2 | 249 | 66 | 84 | 10 | 62 | 1 | 10 | 1,160 | 2 | 5.46 | 1.93 | 2.82 | 0.31 | 15.1 | 5.3 | 1.08 | .262 | 2.62 | 47 | 3.01 | 70 | 7.76 | 40.8 | ||
| 13 | | A. Reynolds | 2.06 | 1952 | 35 | 20 | 8 | .714 | 29 | 160 | 24 | 6 | 6 | 244.1 | 194 | 56 | 70 | 10 | 97 | 7 | 6 | 1,000 | 4 | 5.89 | 3.57 | 1.65 | 0.37 | 16.0 | 9.7 | 1.19 | .253 | 2.58 | 60 | 2.89 | 83 | 7.15 | 16.2 | ||
| 14 | | D. Vance | 2.09 | 1928 | 38 | 22 | 10 | .688 | 32 | 200 | 24 | 4 | 2 | 280.1 | 226 | 65 | 79 | 11 | 72 | 7 | 5 | 1,126 | 1 | 6.42 | 2.31 | 2.78 | 0.35 | 17.8 | 6.4 | 1.06 | .257 | 2.54 | 53 | 2.83 | 70 | 7.26 | 37.6 | ||
| 15 | | T. Lyons | 2.10 | 1942 | 20 | 14 | 6 | .700 | 20 | 50 | 20 | 1 | 0 | 180.1 | 167 | 42 | 52 | 11 | 26 | 2 | 0 | 720 | 3 | 2.50 | 1.30 | 1.92 | 0.55 | 6.9 | 3.6 | 1.07 | .247 | 2.60 | 58 | 3.12 | 89 | 8.33 | 7.3 | ||
| 16 | | H. Pollet | 2.10 | 1946 | 40 | 21 | 10 | .677 | 32 | 107 | 22 | 4 | 5 | 266.0 | 228 | 62 | 84 | 12 | 86 | 5 | 7 | 1,083 | 1 | 3.62 | 2.91 | 1.24 | 0.41 | 9.9 | 7.9 | 1.18 | .247 | 2.84 | 61 | 3.19 | 92 | 7.71 | 8.4 | ||
| 17 | | S. Chandler | 2.10 | 1946 | 34 | 20 | 8 | .714 | 32 | 138 | 20 | 6 | 2 | 257.1 | 200 | 60 | 71 | 7 | 90 | 1 | 2 | 1,028 | 3 | 4.83 | 3.15 | 1.53 | 0.24 | 13.4 | 8.8 | 1.13 | .244 | 2.48 | 60 | 2.73 | 79 | 6.99 | 20.4 | ||
| 18 | | W. Spahn | 2.10 | 1953 | 35 | 23 | 7 | .767 | 32 | 148 | 24 | 5 | 3 | 265.2 | 211 | 62 | 75 | 14 | 70 | 1 | 3 | 1,055 | 3 | 5.01 | 2.37 | 2.11 | 0.47 | 14.0 | 6.6 | 1.06 | .240 | 2.54 | 53 | 2.97 | 76 | 7.15 | 29.2 | ||
| 19 | | D. Trout | 2.12 | 1944 | 49 | 27 | 14 | .659 | 40 | 144 | 33 | 7 | 0 | 352.1 | 314 | 83 | 104 | 9 | 83 | 4 | 6 | 1,421 | 2 | 3.68 | 2.12 | 1.73 | 0.23 | 10.1 | 5.8 | 1.13 | .258 | 2.66 | 59 | 2.79 | 78 | 8.02 | 31 | ||
| 20 | | R. Wolff | 2.12 | 1945 | 33 | 20 | 10 | .667 | 29 | 108 | 21 | 4 | 2 | 250.0 | 200 | 59 | 68 | 7 | 53 | 1 | 4 | 1,000 | 1 | 3.89 | 1.91 | 2.04 | 0.25 | 10.8 | 5.3 | 1.01 | .232 | 2.45 | 66 | 2.69 | 81 | 7.20 | 17.7 | ||
| 21 | | D. Leonard | 2.13 | 1945 | 31 | 17 | 7 | .708 | 29 | 96 | 12 | 4 | 1 | 216.0 | 208 | 51 | 72 | 5 | 35 | 2 | 1 | 885 | 2 | 4.00 | 1.46 | 2.74 | 0.21 | 10.8 | 4.0 | 1.13 | .272 | 3.00 | 66 | 2.47 | 74 | 8.67 | 20.9 | ||
| 22 | | J. Beazley | 2.13 | 1942 | 43 | 21 | 6 | .778 | 23 | 91 | 13 | 3 | 3 | 215.1 | 181 | 51 | 67 | 4 | 73 | 3 | 15 | 890 | 7 | 3.80 | 3.05 | 1.25 | 0.17 | 10.2 | 8.2 | 1.18 | .246 | 2.80 | 63 | 2.87 | 82 | 7.57 | 15.3 | ||
| 23 | | B. Adams | 2.16 | 1920 | 35 | 17 | 13 | .567 | 33 | 84 | 18 | 8 | 2 | 263.0 | 240 | 63 | 83 | 6 | 18 | 1 | 2 | 1,035 | 5 | 2.87 | 0.62 | 4.67 | 0.21 | 8.1 | 1.7 | 0.98 | .253 | 2.84 | 68 | 2.62 | 79 | 8.21 | 20.2 | ||
| 24 | | H. Schumacher | 2.16 | 1933 | 35 | 19 | 12 | .613 | 33 | 96 | 21 | 7 | 1 | 258.2 | 199 | 62 | 71 | 9 | 84 | 1 | 1 | 1,028 | 4 | 3.34 | 2.92 | 1.14 | 0.31 | 9.3 | 8.2 | 1.09 | .227 | 2.47 | 67 | 3.49 | 102 | 6.92 | -3 | ||
| 25 | | D. Vance | 2.16 | 1924 | 35 | 28 | 6 | .824 | 34 | 262 | 30 | 3 | 0 | 308.1 | 238 | 74 | 89 | 11 | 77 | 9 | 1 | 1,221 | 4 | 7.65 | 2.25 | 3.40 | 0.32 | 21.5 | 6.3 | 1.02 | .263 | 2.60 | 58 | 2.64 | 69 | 6.95 | 41.3 | ||
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