Mike Zunino had the highest isolated power with >100 at-bats in 2021, with an isolated power of .342.

	NAME	ISO	AB	SEASON	TM	G	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Mike Zunino M. Zunino	.342	333	2021	TBR	109	64	72	11	2	33	62	34	7	132	0	0	375	186	46	0	1	0	7	.216	.301	.559	.860	59	13.7	.358	134	15.4
2	Byron Buxton B. Buxton	.340	235	2021	MIN	61	50	72	23	0	19	32	13	6	62	9	1	254	152	42	0	0	0	0	.306	.358	.647	1.005	53	21.9	.419	170	21.9
3	Shohei Ohtani S. Ohtani	.335	537	2021	LAA	155	103	138	26	8	46	100	96	4	189	26	10	639	318	80	0	2	20	7	.257	.372	.592	.965	119	41.8	.393	150	39.4
4	Fernando Tatis Jr. F. Tatis Jr.	.328	478	2021	SDP	130	99	135	31	0	42	97	62	2	153	25	4	546	292	73	0	4	6	5	.282	.364	.611	.975	106	39.9	.403	158	40.4
5	Brandon Belt B. Belt	.323	325	2021	SFG	97	65	89	14	2	29	59	48	7	103	3	2	381	194	45	0	1	3	9	.274	.378	.597	.975	75	28.9	.406	159	28.4
6	Ronald Acuña Jr. R. Acuña Jr.	.313	297	2021	ATL	82	72	84	19	1	24	52	49	9	85	17	6	360	177	44	0	5	2	0	.283	.394	.596	.990	73	29.1	.412	158	26.4
7	Bryce Harper B. Harper	.305	488	2021	PHI	141	101	151	42	1	35	84	100	5	134	13	3	599	300	78	2	4	14	12	.309	.429	.615	1.044	130	57.7	.431	171	54
8	Joey Votto J. Votto	.297	448	2021	CIN	129	73	119	23	1	36	99	77	4	127	1	0	533	252	60	0	4	6	7	.266	.375	.563	.938	98	33.9	.391	140	27.4
9	George Springer G. Springer	.291	299	2021	TOR	78	59	79	19	1	22	50	37	4	79	4	1	341	166	42	0	1	1	6	.264	.352	.555	.907	60	18.8	.381	140	16.7
10	Mike Trout M. Trout	.291	117	2021	LAA	36	23	39	8	1	8	18	27	2	41	2	0	146	73	17	0	0	5	0	.333	.466	.624	1.090	34	16.5	.451	189	15.9
11	Vladimir Guerrero Jr. V. Guerrero Jr.	.290	604	2021	TOR	161	123	188	29	1	48	111	86	6	110	4	1	698	363	78	0	2	7	20	.311	.401	.601	1.002	145	60.4	.419	166	56.1
12	Kyle Schwarber K. Schwarber	.288	399	2021	TOT	113	76	106	19	0	32	71	64	6	127	1	1	471	221	51	0	2	1	4	.266	.374	.554	.928	87	30.1	.392	145	26.7
13	Patrick Wisdom P. Wisdom	.287	338	2021	CHC	106	54	78	13	0	28	61	32	4	153	4	1	374	175	41	0	0	1	7	.231	.305	.518	.823	55	9.9	.346	117	8
14	Rhys Hoskins R. Hoskins	.283	389	2021	PHI	107	64	96	29	0	27	71	47	5	108	3	2	443	206	56	0	2	0	7	.247	.334	.530	.864	72	18.3	.364	128	15.6
15	Yasmani Grandal Y. Grandal	.280	279	2021	CWS	93	60	67	9	0	23	62	87	3	82	0	0	375	145	32	1	5	0	15	.240	.420	.520	.939	73	27.2	.402	157	26.3
16	Max Muncy M. Muncy	.278	497	2021	LAD	144	95	124	26	2	36	94	83	11	120	2	1	592	262	64	0	1	5	7	.249	.368	.527	.895	103	31.5	.379	140	29.9
17	Brandon Lowe B. Lowe	.277	535	2021	TBR	149	97	132	31	0	39	99	68	9	167	7	1	615	280	70	0	3	4	2	.247	.340	.523	.863	99	24.9	.363	137	27.8
18	Tyler O'Neill T. O'Neill	.274	482	2021	STL	138	89	138	26	2	34	80	38	13	168	15	4	537	270	62	0	4	0	8	.286	.352	.560	.912	96	30.8	.384	143	29.4
19	Marcus Semien M. Semien	.273	652	2021	TOR	162	115	173	39	2	45	102	66	3	146	15	1	724	351	86	0	3	0	9	.265	.334	.538	.873	120	31.9	.368	131	27.4
20	José Ramírez J. Ramírez	.272	552	2021	CLE	152	111	147	32	5	36	103	72	7	87	27	4	636	297	73	0	5	10	13	.266	.355	.538	.893	107	30.2	.372	140	30.9
21	Salvador Perez S. Perez	.271	620	2021	KCR	161	88	169	24	0	48	121	28	13	170	1	0	665	337	72	0	4	4	14	.273	.316	.544	.859	105	24.6	.359	125	20.4
22	Matt Olson M. Olson	.269	565	2021	OAK	156	101	153	35	0	39	111	88	9	113	4	1	673	305	74	0	11	12	17	.271	.371	.540	.911	117	35.7	.379	147	38.9
23	Franmil Reyes F. Reyes	.268	418	2021	CLE	115	57	106	18	2	30	85	43	2	149	4	1	466	218	50	0	3	3	13	.254	.324	.522	.846	72	15.4	.354	128	15.8
24	Nick Castellanos N. Castellanos	.267	531	2021	CIN	138	95	164	38	1	34	100	41	7	121	3	1	585	306	73	0	6	5	16	.309	.362	.576	.939	108	37.2	.391	140	30
25	Seth Brown S. Brown	.267	281	2021	OAK	111	43	60	13	1	20	48	23	1	89	4	1	307	135	34	0	2	2	1	.214	.274	.480	.754	37	0	.315	104	1.5