The Chicago Cubs have the most games by a team, with 22,413 games.

Interpreted as:

most regular-season games played by a team all-time

	TEAM	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	22,413	.513	11,416	10,836	766,937	103,187	200,795	33,928	7,374	15,395	88,758	68,933	5,316	105,911	15,891	3,095	857,164	295,656	56,697	13,031	2,947	3,530	10,011	.262	.326	.386	.711
2	Braves	22,376	.504	11,189	11,033	766,098	100,033	198,917	32,280	6,313	15,192	87,066	67,906	5,104	101,089	14,148	3,082	854,708	289,399	53,785	12,694	2,906	3,665	10,449	.260	.323	.378	.701
3	Reds	21,998	.504	11,015	10,844	749,489	98,694	195,218	32,548	7,577	14,436	87,809	67,055	5,538	103,233	18,218	3,421	837,992	286,228	54,561	12,671	3,071	3,657	9,793	.260	.325	.382	.707
4	Pirates	21,957	.500	10,908	10,909	751,985	97,586	197,817	32,538	8,948	12,332	87,077	64,673	5,565	100,580	15,745	3,293	838,054	285,247	53,818	12,569	3,139	3,710	10,129	.263	.325	.379	.704
5	Giants	21,882	.535	11,619	10,100	746,721	101,142	196,309	31,511	7,057	15,706	90,592	68,677	5,726	100,534	16,559	3,157	835,858	289,052	54,274	11,680	3,054	4,028	10,258	.263	.328	.387	.716
6	Phillies	21,806	.475	10,300	11,391	746,125	96,885	194,290	33,608	6,695	14,352	87,095	68,089	5,457	106,259	15,040	2,935	834,641	284,344	54,655	11,927	3,043	3,752	9,925	.260	.326	.381	.707
7	Dodgers	21,797	.532	11,521	10,137	742,659	98,447	193,991	31,226	7,018	14,290	88,645	69,290	5,188	101,269	17,396	3,565	833,095	282,123	52,534	12,784	3,098	3,759	10,015	.261	.327	.380	.707
8	Cardinals	20,765	.513	10,583	10,051	710,191	92,869	188,633	31,999	7,056	12,961	84,907	64,500	5,267	99,072	15,070	3,631	795,118	273,627	52,016	11,993	3,167	3,784	10,212	.266	.330	.385	.715
9	Tigers	19,494	.503	9,761	9,640	664,714	89,516	175,540	29,758	6,324	14,714	82,447	65,881	4,491	97,713	11,332	2,948	749,240	262,088	50,796	11,010	3,144	2,455	10,772	.264	.333	.394	.727
10	Twins	19,482	.481	9,328	10,045	664,543	85,649	174,189	29,923	6,346	12,158	78,864	62,714	5,220	95,418	12,100	3,103	745,863	253,278	48,427	10,197	3,189	2,670	11,045	.262	.329	.381	.710
11	Orioles	19,473	.475	9,195	10,168	661,414	84,086	170,594	29,512	4,924	14,565	77,757	63,628	4,527	99,359	10,642	2,808	743,233	253,649	49,001	10,534	3,130	2,587	10,908	.258	.326	.383	.709
12	Guardians	19,470	.513	9,938	9,441	663,473	87,959	175,490	31,319	5,511	14,031	81,313	62,957	4,875	95,536	11,998	3,409	746,172	259,924	50,861	11,483	3,384	2,568	10,578	.265	.331	.392	.723
13	White Sox	19,467	.498	9,652	9,712	659,092	84,532	171,049	28,378	5,559	12,406	77,724	62,432	5,284	92,994	13,669	3,496	742,436	247,763	46,343	12,384	3,244	2,468	10,599	.260	.327	.376	.703
14	Red Sox	19,459	.518	10,042	9,334	665,997	90,908	177,672	33,346	5,615	14,727	84,316	67,154	4,855	96,506	9,722	2,577	751,980	266,429	53,688	10,605	3,369	3,011	11,620	.267	.337	.400	.737
15	Athletics	19,433	.486	9,404	9,942	658,731	85,801	169,542	29,408	5,342	14,297	79,088	64,854	4,767	100,020	12,163	3,228	742,177	252,525	49,047	10,697	3,128	2,281	10,688	.257	.327	.383	.710
16	Yankees	19,172	.569	10,868	8,216	653,399	93,194	173,398	28,802	5,507	17,507	86,615	69,020	4,957	95,850	11,750	2,826	740,296	265,735	51,816	9,601	3,319	2,867	10,757	.265	.339	.407	.745
17	Angels	10,297	.495	5,092	5,202	349,287	44,546	89,259	15,431	1,822	9,369	41,926	32,675	2,891	63,872	6,112	3,119	391,195	136,441	26,622	3,547	2,795	2,500	7,945	.256	.322	.391	.713
18	Rangers	10,285	.477	4,898	5,381	351,090	46,277	90,477	16,144	1,902	10,319	43,732	33,250	2,743	66,091	6,036	2,868	392,913	141,382	28,365	2,971	2,859	2,267	7,861	.258	.324	.403	.727
19	Astros	10,137	.503	5,093	5,039	344,032	43,226	87,683	16,078	2,179	8,553	40,688	32,663	2,948	63,819	7,203	3,149	386,421	133,778	26,810	4,038	2,740	3,154	7,495	.255	.322	.389	.711
20	Mets	10,130	.484	4,897	5,225	342,733	41,877	85,643	15,306	1,825	8,746	39,452	32,781	2,919	65,878	5,993	2,747	385,088	130,837	25,877	4,000	2,655	3,159	7,535	.250	.318	.382	.700
21	Padres	9,005	.468	4,214	4,789	304,394	36,524	75,910	13,444	1,772	7,365	34,352	28,968	2,170	60,282	6,073	2,624	341,558	114,993	22,581	3,748	2,278	2,699	6,573	.249	.317	.378	.695
22	Brewers	9,001	.489	4,404	4,593	305,590	40,102	78,299	14,596	1,769	8,829	37,988	29,430	2,759	59,765	6,083	2,770	343,410	122,920	25,194	3,177	2,454	2,167	6,680	.256	.325	.402	.727
23	Nationals	8,997	.481	4,330	4,663	304,265	37,692	77,163	14,893	1,810	7,707	35,435	28,552	2,661	58,115	6,630	2,809	341,681	118,797	24,410	3,888	2,315	2,891	6,574	.254	.321	.390	.711
24	Royals	8,991	.477	4,287	4,702	307,454	39,299	80,685	15,114	2,302	7,126	37,106	26,297	2,511	52,853	7,157	2,921	341,343	121,781	24,542	2,388	2,693	1,878	6,853	.262	.323	.396	.719
25	Blue Jays	7,710	.500	3,851	3,856	264,155	35,709	68,739	13,736	1,501	8,399	33,881	24,496	2,470	49,692	4,618	1,978	294,800	110,674	23,636	1,525	2,154	1,418	6,023	.260	.326	.419	.745