Babe Ruth has crushed the most career homers versus the Washington Senators, with 89 home runs.

Interpreted as:

most hr by a player against twins all-time

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Babe Ruth B. Ruth	89	349	1,191	276	395	75	34	294	239	6	198	21		1,457	805	198	21				.332	.446	.676	1.122
2	Mickey Mantle M. Mantle	72	304	1,071	216	313	37	11	183	190	2	214	17	3	1,272	588	120	2	7	12	12	.292	.398	.549	.947
3	Jimmie Foxx J. Foxx	69	309	1,099	247	363	64	28	269	202	2	159	16		1,314	690	161	11			8	.330	.435	.628	1.063
4	Jim Thome J. Thome	61	196	695	148	218	34	3	156	118	6	221	2	2	826	441	98	1	6	9	12	.314	.415	.635	1.049
5	Joe DiMaggio J. DiMaggio	58	257	1,002	206	337	62	24	251	117	5	58	3	0	1,124	621	144	0			26	.336	.408	.620	1.028
6	Ted Williams T. Williams	56	331	1,093	262	387	91	21	230	297	5	94	3	0	1,398	688	168	1	2	15	29	.354	.493	.629	1.123
7	Rocky Colavito R. Colavito	55	215	766	129	226	38	4	171	129	7	88	2	4	911	437	97	1	8	13	25	.295	.398	.570	.968
8	Frank Thomas F. Thomas	52	186	668	119	194	42	0	142	103	3	118	2	1	784	392	94	0	10	3	20	.290	.383	.587	.969
9	Al Kaline A. Kaline	52	338	1,189	205	368	64	10	212	153	7	121	13	11	1,367	608	126	1	17	10	30	.310	.387	.511	.898
10	Alex Rodriguez A. Rodriguez	51	150	573	116	181	22	3	130	67	5	96	14	1	653	362	76	1	7	6	15	.316	.388	.632	1.020
11	Reggie Jackson R. Jackson	51	252	902	144	225	54	4	142	102	9	243	9	8	1,018	440	109	1	4	13	20	.249	.330	.488	.818
12	Paul Konerko P. Konerko	50	257	926	131	265	38	3	136	87	8	139	1	0	1,030	459	91	0	9	3	24	.286	.350	.496	.845
13	Lou Gehrig L. Gehrig	48	313	1,147	237	367	68	23	248	213	7	123	11		1,376	625	139	9			0	.320	.429	.545	.974
14	Miguel Cabrera M. Cabrera	47	242	895	133	272	52	1	169	95	7	167	1	3	1,003	467	100	0	6	17	36	.304	.373	.522	.895
15	Eddie Murray E. Murray	44	168	658	102	201	33	1	133	61	1	94	3	1	727	368	78	1	6	9	19	.305	.362	.559	.922
16	Carl Yastrzemski C. Yastrzemski	43	297	1,094	163	321	68	4	158	139	7	121	10	5	1,250	526	115	1	9	11	31	.293	.374	.481	.855
17	Larry Doby L. Doby	43	212	756	144	230	32	6	167	110	4	88	11	2	878	403	81	3	5	0	18	.304	.393	.533	.926
18	Al Simmons A. Simmons	43	264	1,029	182	357	55	30	228	84	2	86	15		1,125	601	128	10			0	.347	.397	.584	.981
19	Ken Griffey Jr. K. Griffey Jr.	42	138	528	102	151	28	1	116	59	3	89	10	5	595	307	71	0	5	14	7	.286	.358	.581	.939
20	Hank Greenberg H. Greenberg	42	176	658	146	227	56	14	171	96	0	85	6		763	437	112	9			6	.345	.428	.664	1.093
21	Gus Zernial G. Zernial	40	171	584	93	177	31	2	137	48	5	77	0	0	642	332	73	0	5	0	9	.303	.358	.568	.927
22	Juan Gonzalez J. Gonzalez	39	141	563	92	166	33	3	115	25	7	101	2	2	602	322	75	0	7	5	15	.295	.329	.572	.901
23	Yogi Berra Y. Berra	39	283	1,018	162	297	51	4	191	95	7	54	4	2	1,130	473	94	1	9	7	15	.292	.353	.465	.818
24	Fred Lynn F. Lynn	38	150	542	105	176	39	5	126	64	1	76	8	3	611	339	82	1	3	5	12	.325	.395	.625	1.021
25	Magglio Ordonez M. Ordonez	37	195	739	115	240	45	2	145	48	2	80	6	5	796	400	84	0	7	2	17	.325	.364	.541	.906