Since 2000, the New York Yankees have the most road wins by a team, with 1,108 wins.

Interpreted as:

team most regular-season wins on road, MLB, since 2000

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	1,108	946	.539	2,055	72,191	10,269	18,655	3,676	302	2,610	9,815	7,572	822	15,813	1,272	444	81,496	30,765	6,588	308	603	410	1,776	.258	.333	.426	.759
2	Dodgers	1,087	967	.529	2,054	72,112	9,862	18,593	3,695	440	2,224	9,388	7,291	798	15,629	1,178	447	81,408	29,840	6,359	613	594	530	1,603	.258	.330	.414	.744
3	Red Sox	1,064	990	.518	2,054	72,577	9,919	18,581	3,693	305	2,543	9,478	7,176	765	15,972	1,155	402	81,377	30,513	6,541	272	587	457	1,662	.256	.327	.420	.747
4	Braves	1,056	997	.514	2,053	71,896	9,582	18,367	3,752	293	2,409	9,172	6,804	636	15,854	1,023	402	80,482	29,932	6,454	663	483	531	1,650	.255	.323	.416	.740
5	Cardinals	1,048	1,004	.511	2,052	71,632	9,704	18,463	3,646	305	2,405	9,238	6,720	851	15,722	973	415	80,434	29,934	6,356	676	555	529	1,654	.258	.326	.418	.744
6	Guardians	1,005	1,051	.489	2,056	71,858	9,577	18,348	3,754	395	2,288	9,145	6,690	843	15,432	1,252	461	80,439	29,756	6,437	440	608	376	1,569	.255	.324	.414	.738
7	Angels	990	1,064	.482	2,054	71,657	9,533	18,399	3,592	360	2,233	9,049	6,315	765	15,011	1,403	584	79,730	29,410	6,185	409	584	439	1,619	.257	.321	.410	.732
8	Giants	987	1,064	.481	2,052	71,684	9,294	18,065	3,582	335	2,284	8,889	6,609	730	15,721	923	397	80,191	29,169	6,201	611	557	584	1,612	.252	.319	.407	.726
9	Astros	983	1,071	.479	2,055	71,693	9,399	18,248	3,686	266	2,287	8,959	6,504	789	15,457	1,193	488	80,131	29,327	6,239	576	569	380	1,683	.255	.321	.409	.730
10	Athletics	977	1,076	.476	2,053	71,686	9,501	17,962	3,654	271	2,393	9,069	6,980	762	15,944	1,019	353	80,226	29,337	6,318	255	543	295	1,641	.251	.321	.409	.731
11	Phillies	976	1,079	.475	2,055	71,832	9,212	18,114	3,658	378	2,170	8,771	6,834	782	16,216	1,383	384	80,567	29,038	6,206	597	522	567	1,476	.252	.322	.404	.726
12	Mariners	968	1,085	.472	2,053	72,336	9,576	18,695	3,618	325	2,305	9,109	6,375	812	15,411	1,337	514	80,485	29,878	6,248	396	566	394	1,525	.258	.323	.413	.736
13	Mets	965	1,089	.470	2,054	71,691	9,453	18,378	3,678	356	2,254	8,989	6,695	821	15,629	1,309	446	80,396	29,530	6,288	659	530	502	1,639	.256	.325	.412	.737
14	Cubs	959	1,093	.467	2,053	71,633	9,143	17,926	3,684	341	2,317	8,727	6,584	788	16,574	1,074	439	80,128	29,243	6,342	626	497	454	1,517	.250	.318	.408	.726
15	Blue Jays	952	1,101	.464	2,053	71,822	9,492	18,294	3,660	271	2,372	9,062	6,611	724	15,272	997	423	80,036	29,612	6,303	322	557	300	1,676	.255	.322	.412	.734
16	Brewers	949	1,106	.462	2,056	71,415	9,106	17,977	3,570	320	2,272	8,694	6,539	910	16,877	1,387	522	79,952	29,003	6,162	602	486	438	1,633	.252	.320	.406	.727
17	Twins	947	1,108	.461	2,055	71,863	9,303	18,243	3,645	327	2,197	8,819	6,457	713	15,718	1,055	489	79,942	29,133	6,169	361	548	370	1,657	.254	.319	.405	.725
18	Diamondbacks	933	1,122	.454	2,055	71,316	8,837	17,416	3,491	352	2,183	8,431	6,692	666	16,418	1,243	437	79,843	28,160	6,026	622	547	486	1,454	.244	.313	.395	.708
19	Rays	922	1,133	.449	2,055	71,719	9,239	18,088	3,654	361	2,283	8,829	6,454	732	16,546	1,491	573	79,773	29,313	6,298	320	548	281	1,489	.252	.318	.409	.727
20	Padres	918	1,138	.446	2,056	71,518	9,254	18,116	3,659	335	2,104	8,816	6,548	670	16,100	1,306	454	79,907	28,757	6,098	599	572	401	1,526	.253	.319	.402	.722
21	Reds	917	1,138	.446	2,055	71,101	8,807	17,566	3,510	350	2,126	8,389	6,496	882	16,564	1,360	509	79,701	28,154	5,986	721	501	463	1,550	.247	.316	.396	.712
22	White Sox	913	1,142	.444	2,055	71,591	8,987	18,235	3,587	309	2,136	8,610	5,720	742	15,719	1,145	526	79,057	28,848	6,032	455	549	252	1,652	.255	.314	.403	.717
23	Rangers	905	1,149	.441	2,054	71,774	9,216	17,932	3,590	284	2,347	8,765	6,094	724	16,145	1,196	449	79,506	29,131	6,221	375	539	343	1,453	.250	.313	.406	.719
24	Nationals	903	1,153	.439	2,056	70,946	8,821	17,727	3,546	348	2,083	8,391	6,531	762	16,083	1,298	539	79,502	28,218	5,977	727	536	477	1,534	.250	.318	.398	.715
25	Tigers	893	1,161	.435	2,054	71,883	9,063	18,260	3,642	359	2,186	8,682	6,033	639	16,711	980	443	79,439	29,178	6,187	370	514	321	1,577	.254	.315	.406	.721