Regular Season
| Season | TM | G | GS | W | L | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | WHIP |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1955 | DET | 15 | 8 | 3 | 5 | 6.35 | 37 | 0 | 0 | 1 | 51.0 | 59 | 36 | 38 | 8 | 32 | 3 | 1.78 |
| 1956 | DET | 15 | 3 | 5 | 1 | 3.71 | 34 | 0 | 0 | 1 | 53.1 | 55 | 22 | 24 | 6 | 28 | 0 | 1.56 |
| 1957 | DET | 45 | 30 | 20 | 8 | 2.69 | 182 | 14 | 1 | 1 | 267.1 | 214 | 80 | 91 | 33 | 72 | 11 | 1.07 |
| 1958 | DET | 35 | 34 | 14 | 12 | 3.52 | 177 | 10 | 3 | 0 | 219.2 | 188 | 86 | 96 | 28 | 79 | 10 | 1.22 |
| 1959 | DET | 40 | 35 | 17 | 13 | 3.89 | 201 | 14 | 1 | 1 | 249.2 | 220 | 108 | 111 | 37 | 75 | 11 | 1.18 |
| 1960 | DET | 36 | 34 | 11 | 14 | 2.79 | 201 | 10 | 3 | 0 | 252.0 | 217 | 78 | 92 | 20 | 64 | 11 | 1.12 |
| 1961 | DET | 38 | 37 | 17 | 11 | 3.19 | 194 | 12 | 4 | 1 | 268.0 | 232 | 95 | 113 | 25 | 71 | 9 | 1.13 |
| 1962 | DET | 41 | 35 | 19 | 10 | 3.59 | 184 | 12 | 2 | 6 | 258.0 | 262 | 103 | 112 | 28 | 74 | 13 | 1.30 |
| 1963 | DET | 39 | 35 | 12 | 13 | 3.88 | 196 | 6 | 2 | 1 | 248.1 | 245 | 107 | 119 | 38 | 69 | 5 | 1.26 |
| 1964 | PHI | 41 | 39 | 19 | 8 | 2.63 | 219 | 13 | 5 | 2 | 284.1 | 248 | 83 | 99 | 23 | 46 | 14 | 1.03 |
| 1965 | PHI | 39 | 39 | 19 | 9 | 2.60 | 268 | 15 | 7 | 0 | 291.0 | 253 | 84 | 92 | 23 | 62 | 12 | 1.08 |
| 1966 | PHI | 43 | 41 | 19 | 14 | 2.41 | 252 | 16 | 5 | 1 | 314.0 | 260 | 84 | 91 | 26 | 55 | 19 | 1.00 |
| 1967 | PHI | 40 | 40 | 17 | 15 | 2.29 | 253 | 16 | 6 | 0 | 302.1 | 241 | 77 | 94 | 18 | 73 | 13 | 1.04 |
| 1968 | PIT | 27 | 26 | 4 | 14 | 3.88 | 95 | 3 | 1 | 0 | 160.0 | 168 | 69 | 75 | 14 | 48 | 8 | 1.35 |
| 1969 | PIT | 25 | 25 | 10 | 9 | 3.81 | 124 | 4 | 0 | 0 | 156.0 | 147 | 66 | 74 | 10 | 49 | 6 | 1.26 |
| 1969 | LAD | 9 | 9 | 3 | 1 | 3.36 | 33 | 1 | 0 | 0 | 56.1 | 65 | 21 | 23 | 5 | 10 | 1 | 1.33 |
| 1969 | TOT | 34 | 34 | 13 | 10 | 3.69 | 157 | 5 | 0 | 0 | 212.1 | 212 | 87 | 97 | 15 | 59 | 7 | 1.28 |
| 1970 | PHI | 34 | 33 | 10 | 15 | 4.11 | 147 | 4 | 0 | 0 | 219.0 | 233 | 100 | 111 | 19 | 56 | 8 | 1.32 |
| 1971 | PHI | 29 | 16 | 5 | 12 | 5.48 | 58 | 1 | 0 | 1 | 110.0 | 126 | 67 | 72 | 11 | 37 | 6 | 1.48 |
| Career | 591 | 519 | 224 | 184 | 3.27 | 2,855 | 151 | 40 | 16 | 3760.1 | 3,433 | 1,366 | 1,527 | 372 | 1,000 | 160 | 1.18 |
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