Summit Therapeutics (SMMT) had the highest return on December 27, 2019 by a large-cap US stock, returning 2.6%.

ASSET	DATE	% RETURN
Summit Therapeutics (SMMT)	12/27/2019	2.65%
Super Micro Computer (SMCI)	12/27/2019	2.55%
Five Below (FIVE)	12/27/2019	1.88%
Woori Financial (WF)	12/27/2019	1.71%
WESCO International (WCC)	12/27/2019	1.38%
Rentokil Initial (RTO)	12/27/2019	1.32%
Dick’s Sporting Goods (DKS)	12/27/2019	1.28%
General Mills (GIS)	12/27/2019	1.2%
Zillow Group Inc Class C (Z)	12/27/2019	1.12%
Ensign (ENSG)	12/27/2019	1.11%
McCormick (MKC)	12/27/2019	1.1%
Shinhan Financial (SHG)	12/27/2019	1.1%
ZTO Express (Cayman) (ZTO)	12/27/2019	1.07%
Celsius (CELH)	12/27/2019	1.07%
Arch Capital (ACGL)	12/27/2019	0.95%
Renaissancere (RNR)	12/27/2019	0.94%
Texas Pacific Land Trust (TPL)	12/27/2019	0.94%
Viatris (VTRS)	12/27/2019	0.87%
Roper Technologies (ROP)	12/27/2019	0.82%
America Movil SAB de CV ADR (AMX)	12/27/2019	0.8%
Brookfield Renewable Partners (BEP)	12/27/2019	0.8%
IDEXX Laboratories (IDXX)	12/27/2019	0.79%
Alcoa (AA)	12/27/2019	0.79%
Dollar Tree (DLTR)	12/27/2019	0.79%
Dollar General (DG)	12/27/2019	0.75%

Large-cap stocks are treated as having a market cap of $10B+.