Ferguson (FERG) had the highest return between 2005 and 2010 by a large-cap US stock, returning 16,666.5%.

ASSET	YEARS	% RETURN
Ferguson (FERG)	2005-2010	16,666.53%
Booking (BKNG)	2005-2010	1,584.44%
Baidu (BIDU)	2005-2010	1,362.58%
Netflix (NFLX)	2005-2010	1,307.82%
Illumina (ILMN)	2005-2010	1,244.8%
Wheaton Precious Metals (WPM)	2005-2010	1,223.41%
Ambev SA ADR (ABEV)	2005-2010	1,172.28%
Monster Beverage (MNST)	2005-2010	1,018.54%
Apple (AAPL)	2005-2010	895.9%
Southern Copper (SCCO)	2005-2010	863.5%
Credicorp (BAP)	2005-2010	793.85%
CF Industries (CF)	2005-2010	749.98%
Salesforce (CRM)	2005-2010	704.39%
Banco Bradesco SA ADR (BBD)	2005-2010	663.52%
Trip Group Ltd ADR (TCOM)	2005-2010	616.3%
Suzano Papel e Celulose SA ADR (SUZ)	2005-2010	601.3%
Intuitive Surgical (ISRG)	2005-2010	544.06%
Alamos Gold (AGI)	2005-2010	539.01%
TechnipFMC (FTI)	2005-2010	492.78%
Agnico Eagle Mines (AEM)	2005-2010	471.35%
Tenaris SA ADR (TS)	2005-2010	469.87%
Cummins (CMI)	2005-2010	468.96%
Mastercard (MA)	2005-2010	464.18%
Companhia de Saneamento Basico do Estado de Sao Paulo SABESP ADR (SBS)	2005-2010	454.75%
Clean Harbors (CLH)	2005-2010	453.16%

Large-cap stocks are treated as having a market cap of $10B+.