best performing large stocks 2000 to 2025

QXO (QXO) had the highest return between 2000 and 2025 by a large-cap US stock, returning 1,134,605.9%.

ASSETYEARS% RETURN
QXO (QXO)
2000-2025
1,134,605.88%
NVIDIA (NVDA)
2000-2025
206,662.75%
Monster Beverage (MNST)
2000-2025
171,805.83%
Axon Enterprise (AXON)
2000-2025
97,264.99%
Netflix (NFLX)
2000-2025
81,007.27%
Deckers Outdoor (DECK)
2000-2025
71,004.25%
Texas Pacific Land Trust (TPL)
2000-2025
45,928.85%
Clean Harbors (CLH)
2000-2025
38,377.19%
Tesla (TSLA)
2000-2025
35,403.28%
Old Dominion Freight Line (ODFL)
2000-2025
34,567.26%
Apple (AAPL)
2000-2025
34,473.05%
Tractor Supply (TSCO)
2000-2025
30,338.22%
Broadcom (AVGO)
2000-2025
29,260.37%
Intuitive Surgical (ISRG)
2000-2025
28,219.42%
Sterling Construction (STRL)
2000-2025
24,398.4%
NetEase (NTES)
2000-2025
22,829.02%
Altria (MO)
2000-2025
20,067.89%
Southern Copper (SCCO)
2000-2025
20,044.82%
IDEXX Laboratories (IDXX)
2000-2025
16,771.07%
Comfort Systems USA (FIX)
2000-2025
15,684.23%
Waste Connections (WCN)
2000-2025
15,649.96%
Mastercard (MA)
2000-2025
15,489.33%
CoreSite Realty (COR)
2000-2025
15,297.06%
Transdigm (TDG)
2000-2025
15,262.62%
NVR (NVR)
2000-2025
15,172.82%
Large-cap stocks are treated as having a market cap of $10B+.