National Grid PLC ADR (NGG) had the highest return between 2002 and 2007 by a large-cap US stock, returning 1,149,159.1%.

ASSET	YEARS	% RETURN
National Grid PLC ADR (NGG)	2002-2007	1,149,159.09%
NetEase (NTES)	2002-2007	10,027.03%
Canadian Pacific Railway (CP)	2002-2007	8,660.21%
Monster Beverage (MNST)	2002-2007	8,250.23%
Cheniere Energy (LNG)	2002-2007	6,772.05%
ArcelorMittal SA ADR (MT)	2002-2007	4,716.13%
Deckers Outdoor (DECK)	2002-2007	3,407.49%
Bancolombia SA ADR (CIB)	2002-2007	2,675.17%
Southern Copper (SCCO)	2002-2007	2,557.11%
Vale SA ADR (VALE)	2002-2007	2,472.3%
CME (CME)	2002-2007	1,724.78%
Apple (AAPL)	2002-2007	1,696.38%
Intuitive Surgical (ISRG)	2002-2007	1,547.87%
Tenaris SA ADR (TS)	2002-2007	1,465.73%
Clean Harbors (CLH)	2002-2007	1,443.28%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2002-2007	1,392.46%
Hologic (HOLX)	2002-2007	1,376.13%
ICICI Bank (IBN)	2002-2007	1,364.32%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2002-2007	1,265.02%
Canadian Natural Resources (CNQ)	2002-2007	1,173.65%
Axon Enterprise (AXON)	2002-2007	1,163.28%
First Solar (FSLR)	2002-2007	990.37%
Steel Dynamics (STLD)	2002-2007	970.99%
Credicorp (BAP)	2002-2007	962.81%
America Movil SAB de CV ADR (AMX)	2002-2007	931.28%

Large-cap stocks are treated as having a market cap of $10B+.