Bright Minds Biosciences (DRUG) had the highest return last year by a small-cap US stock, returning 2,317.4%.

ASSET	YEAR	% RETURN
Bright Minds Biosciences (DRUG)	2024	2,317.45%
Red Cat (RCAT)	2024	1,343.82%
Power Solutions International, Inc Common Stock (PSIX)	2024	1,337.2%
Exodus Movement (EXOD)	2024	1,233.91%
Monopar Therapeutics (MNPR)	2024	1,229.31%
Alliance Entertainment Holding Corporation Class A Common Stock (AENT)	2024	829.23%
Mesoblast (MESO)	2024	816.67%
United States Antimony (UAMY)	2024	613.71%
Root (ROOT)	2024	596.64%
Nano Nuclear Energy Inc Common Stock (NNE)	2024	591.53%
Intuitive Machines (LUNR)	2024	590.49%
POET Technologies (POET)	2024	489.11%
Candel Therapeutics (CADL)	2024	482.55%
Redwire (RDW)	2024	467.59%
TheRealReal (REAL)	2024	452.02%
SEALSQ (LAES)	2024	412.5%
Janux Therapeutics (JANX)	2024	401.31%
Innodata (INOD)	2024	394%
DeFi Technologies (DEFT)	2024	365.43%
Byrna Technologies (BYRN)	2024	357.3%
Cango (CANG)	2024	344.44%
Willis Lease Finance (WLFC)	2024	339.91%
Unusual Machines (UMAC)	2024	320.5%
Emergent Biosolutions (EBS)	2024	306.81%
Benitec Biopharma Ltd ADR (BNTC)	2024	293.46%

Small-cap stocks are treated as having a market cap between $300M and $2B.