Amerant Bancorp (AMTB) had the highest return between 2017 and 2022 by a US stock, returning 8,533,633.3%.

ASSET	YEARS	% RETURN
Amerant Bancorp (AMTB)	2017-2022	8,533,633.33%
BioNexus Gene Lab Corp Common stock (BGLC)	2017-2022	2,780,387.8%
KULR Technology (KULR)	2017-2022	2,399,900%
Weatherford International (WFRD)	2017-2022	1,469,264.71%
MDxHealth SA ADR (MDXH)	2017-2022	1,321,900%
Diversified Energy (DEC)	2017-2022	579,200%
Avalon GloboCare (ALBT)	2017-2022	466,965.87%
GreenPower Motor (GP)	2017-2022	233,683.78%
Immatics (IMTX)	2017-2022	174,100%
MicroCloud Hologram (HOLO)	2017-2022	131,516.22%
Integra Resources (ITRG)	2017-2022	126,500%
Castellum (CTM)	2017-2022	66,215.79%
Freedom (FRHC)	2017-2022	42,241.82%
Bone Biologics (BBLG)	2017-2022	27,143.24%
Enphase Energy (ENPH)	2017-2022	25,876.47%
GT Biopharma (GTBP)	2017-2022	23,013.04%
Applied Digital (APLD)	2017-2022	18,300%
GeoVax Labs (GOVX)	2017-2022	15,141.94%
Kaival Brands Innovations (KAVL)	2017-2022	14,858.33%
AquaBounty Technologies (AQB)	2017-2022	10,511.11%
ABOT (ABOT)	2017-2022	8,564.9%
Alarum Technologies (ALAR)	2017-2022	6,979.65%
FitLife Brands, Inc Common Stock (FTLF)	2017-2022	6,618.62%
FingerMotion (FNGR)	2017-2022	5,520%
Zynex (ZYXI)	2017-2022	4,972.94%