GeoVax Labs (GOVX) had the highest return between 2009 and 2016 by a US stock, returning 5,263,157,794.2%.

ASSET	YEARS	% RETURN
GeoVax Labs (GOVX)	2009-2016	5,263,157,794.21%
LM Funding America (LMFA)	2009-2016	4,111,011.11%
QXO (QXO)	2009-2016	3,450,050%
Aurora Cannabis (ACB)	2009-2016	2,653,709.33%
Blackboxstocks (BLBX)	2009-2016	2,470,488.24%
Sequans Communications (SQNS)	2009-2016	2,252,912.05%
TCTM Kids IT Education (VSA)	2009-2016	477,949.73%
Processa Pharmaceuticals (PCSA)	2009-2016	291,566.67%
Prairie Operating Co Common Stock (PROP)	2009-2016	177,939.2%
Akari Therapeutics (AKTX)	2009-2016	112,540%
Nutex Health (NUTX)	2009-2016	69,900%
Anfield Energy (AEC)	2009-2016	33,127.85%
NextTrip (NTRP)	2009-2016	21,500%
Patrick Industries (PATK)	2009-2016	18,971.68%
Cementos Pacasmayo SAA ADR (CPAC)	2009-2016	14,140.94%
ACCESS Newswire (ACCS)	2009-2016	13,718.58%
Pioneer Power Solutions (PPSI)	2009-2016	11,811.54%
Nexstar Broadcasting (NXST)	2009-2016	10,006.59%
Sleep Number (SNBR)	2009-2016	8,600%
Natural Health Trend (NHTC)	2009-2016	8,449.8%
MGP Ingredients (MGPI)	2009-2016	7,715.06%
Mitek Systems (MITK)	2009-2016	7,587.5%
OrganiGram (OGI)	2009-2016	6,968.42%
Metalla Royalty & Streaming (MTA)	2009-2016	6,836.75%
Eastside Distilling (BLNE)	2009-2016	5,845.95%