Know Labs (KNW) had the highest return between 2002 and 2008 by a US stock, returning 534,224.4%.

ASSET	YEARS	% RETURN
Know Labs (KNW)	2002-2008	534,224.43%
Perspective Therapeutics (CATX)	2002-2008	66,566.67%
Frontline (FRO)	2002-2008	25,365.9%
Future Fintech (FTFT)	2002-2008	12,400%
NetEase (NTES)	2002-2008	11,688.93%
Ainos (AIMD)	2002-2008	10,350%
TherapeuticsMD (TXMD)	2002-2008	7,439.95%
Houston American Energy (HUSA)	2002-2008	6,731.48%
Monster Beverage (MNST)	2002-2008	6,221.72%
Gulf Resources (GURE)	2002-2008	5,900%
Broadwind Energy (BWEN)	2002-2008	5,300.22%
Companhia Siderurgica Nacional ADR (SID)	2002-2008	5,271.96%
USANA Health Sciences (USNA)	2002-2008	5,169.31%
Sohu (SOHU)	2002-2008	3,911.86%
Insteel Industries (IIIN)	2002-2008	3,734.19%
Oramed Pharmaceuticals (ORMP)	2002-2008	3,134.28%
Companhia Energetica de Minas Gerais CEMIG Pref ADR (CIG)	2002-2008	2,712.24%
Encore Capital (ECPG)	2002-2008	2,669.23%
DXP Enterprises (DXPE)	2002-2008	2,556.36%
EZCORP (EZPW)	2002-2008	2,463.63%
PetMed Express (PETS)	2002-2008	2,315.1%
MEDIFAST (MED)	2002-2008	2,300.11%
CervoMed (CRVO)	2002-2008	2,122.22%
Bancolombia SA ADR (CIB)	2002-2008	1,891.11%
Diamond Hill Investment (DHIL)	2002-2008	1,829.52%