QVC (QVCGA) had the best year in the 2000s by a US stock in 2006, returning 11,185,255.6%.

ASSET	YEAR	% RETURN
QVC (QVCGA)	2006	11,185,255.56%
India Globalization Capital (IGC)	2006	9,733,233.33%
Natwest (NWG)	2007	9,034,940%
Know Labs (KNW)	2006	7,785,769.97%
InterContinental Hotels Group PLC ADR (IHG)	2003	5,929,900%
Hirequest (HQI)	2003	3,889,000%
Ageagle Aerial Systems (UAVS)	2007	3,199,897.9%
Perspective Therapeutics (CATX)	2005	2,416,566.67%
Northern Oil & Gas (NOG)	2007	2,278,907.69%
National Grid PLC ADR (NGG)	2005	700,019.05%
Ring Energy (REI)	2007	263,900%
Ocean Power Technologies (OPTT)	2006	188,788.89%
Gladstone Capital (GLAD)	2002	176,404.17%
Houston American Energy (HUSA)	2002	93,093.14%
Cryoport (CYRX)	2005	71,251.35%
Theriva Biologics (TOVX)	2006	57,400.01%
Gyre Therapeutics (GYRE)	2006	19,089.16%
NanoViricides (NNVC)	2005	17,700%
OPTIMIZERx (OPRX)	2005	13,900%
Xcel Brands (XELB)	2001	10,000%
Future Fintech (FTFT)	2008	9,900%
Oramed Pharmaceuticals (ORMP)	2004	8,275.95%
Titan Pharmaceuticals (TTNP)	2009	8,150%
Weatherford International (WFRD)	2008	7,300%
Metalla Royalty & Streaming (MTA)	2009	6,281.93%