NVIDIA (NVDA) has had the highest return between 2020 and 2025 by a US stock in the S&P 500 (GSPC), returning 3,066.2%.

ASSET	YEARS	% RETURN
NVIDIA (NVDA)	2020-2025	3,066.18%
Palantir Technologies Inc Class A Common Stock (PLTR)	2020-2025	1,679.3%
Super Micro Computer (SMCI)	2020-2025	1,567.09%
Tesla (TSLA)	2020-2025	1,417.74%
Broadcom (AVGO)	2020-2025	1,169.45%
Quanta Services (PWR)	2020-2025	998.07%
Crowdstrike (CRWD)	2020-2025	978.97%
Arista Networks (ANET)	2020-2025	947.45%
Constellation Energy (CEG)	2020-2025	874.25%
Vistra Energy (VST)	2020-2025	846.94%
Applovin (APP)	2020-2025	785.61%
Howmet Aerospace (HWM)	2020-2025	784.33%
Axon Enterprise (AXON)	2020-2025	713.98%
EMCOR (EME)	2020-2025	662.04%
Eli Lilly and (LLY)	2020-2025	652.78%
KLA-Tencor (KLAC)	2020-2025	608.19%
McKesson (MCK)	2020-2025	537.02%
Dell Technologies (DELL)	2020-2025	506.69%
Williams-Sonoma (WSM)	2020-2025	503.9%
Interactive Brokers (IBKR)	2020-2025	502.52%
Seagate Technology (STX)	2020-2025	478.36%
Lam Research (LRCX)	2020-2025	477.4%
EQT (EQT)	2020-2025	465.79%
GE Aerospace (GE)	2020-2025	463.8%
Monolithic Power Systems (MPWR)	2020-2025	455.44%