Olema Pharmaceuticals (OLMA) has had the highest return this month by a US stock with a market cap of $2B+, returning 212.4%.

ASSET	MONTH	% RETURN
Olema Pharmaceuticals (OLMA)	November 2025	212.44%
PACS (PACS)	November 2025	165.57%
Cogent Biosciences (COGT)	November 2025	148.55%
Terns Pharmaceuticals (TERN)	November 2025	104.63%
Cidara Therapeutics (CDTX)	November 2025	103.15%
Inspire Medical Systems (INSP)	November 2025	76.7%
Haemonetics (HAE)	November 2025	61.82%
EXACT Sciences (EXAS)	November 2025	56.32%
McGraw Hill (MH)	November 2025	55.3%
Globus Medical (GMED)	November 2025	51.3%
Kohl's (KSS)	November 2025	50.16%
Nuvation Bio (NUVB)	November 2025	50%
Lumentum (LITE)	November 2025	47.72%
Scholar Rock (SRRK)	November 2025	46.82%
Zymeworks Inc Common Stock (ZYME)	November 2025	43.84%
Polibeli Group Ltd Class A Ordinary Shares (PLBL)	November 2025	43.27%
Progyny (PGNY)	November 2025	42.7%
Madrigal Pharmaceuticals (MDGL)	November 2025	42.55%
Aris Mining (ARMN)	November 2025	41.9%
Brinker International (EAT)	November 2025	41.41%
Seaboard (SEB)	November 2025	39.92%
Edgewise Therapeutics (EWTX)	November 2025	39.61%
Compass (COMP)	November 2025	37.47%
Arrowhead Pharmaceuticals (ARWR)	November 2025	37.44%
10X Genomics (TXG)	November 2025	37.16%