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biggest stock gainers since sep 2025

Vyne Therapeutics (VYNE) has had the highest return since September 30, 2025 by a US stock, returning 801,215.8%.

ASSET% RETURN
Vyne Therapeutics (VYNE)
801,215.79%
WhiteHawk Minerals (WHK)
436,733.33%
Aptorum Group Ltd Class A (APM)
420,400%
Seaport Therapeutics, Inc Common Stock (SPTX)
239,600%
SharonAI Holdings, Inc Class A Common Stock (SHAZ)
138,569.35%
Mega Fortune Company Limited Ordinary Shares (MGRT)
2,046.41%
CBL International Limited Ordinary Shares (BANL)
1,672.86%
AXT (AXTI)
1,576.37%
Sandisk (SNDK)
1,324.87%
Trinity Biotech (TRIB)
1,109.14%
Climb Bio (CLYM)
773.87%
Erasca (ERAS)
766.03%
Damora Therapeutics (DMRA)
764.13%
Alto Neuroscience (ANRO)
753.25%
Sellas Life Sciences (SLS)
739.74%
Q32 Bio (QTTB)
688.14%
Adlai Nortye Ltd American Depositary Shares (ANL)
686.67%
Praxis Precision Medicines  (PRAX)
616.61%
Spyre Therapeutics (SYRE)
560.26%
Charming Medical Limited Class A Ordinary Shares (MCTA)
539.54%
Alumis (ALMS)
536.32%
Oruka Therapeutics (ORKA)
493.6%
Micron Technology (MU)
474.17%
Immix Biopharma (IMMX)
473.3%
Talkspace (TALK)
458.18%

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