Antero Resources (AR) had the lowest return between 2014 and 2019 by a large-cap US stock, returning -95.3%.

ASSET	YEARS	% RETURN
Antero Resources (AR)	2014-2019	-95.31%
Range Resources (RRC)	2014-2019	-93.98%
Summit Therapeutics (SMMT)	2014-2019	-83.84%
GameStop (GME)	2014-2019	-82.83%
Deutsche Bank (DB)	2014-2019	-81.07%
EQT (EQT)	2014-2019	-77.28%
Teva Pharma Industries Ltd ADR (TEVA)	2014-2019	-72.65%
Ovintiv (OVV)	2014-2019	-71.78%
PG&E (PCG)	2014-2019	-69.39%
ArcelorMittal SA ADR (MT)	2014-2019	-65.5%
Canadian Pacific Railway (CP)	2014-2019	-65.1%
YPF Sociedad Anonima (YPF)	2014-2019	-63.56%
Freeport-McMoran Copper & Gold (FCX)	2014-2019	-61.77%
Cemex SAB de CV ADR (CX)	2014-2019	-61.36%
United States Steel (X)	2014-2019	-59.62%
Cenovus Energy (CVE)	2014-2019	-58.84%
TechnipFMC (FTI)	2014-2019	-55.89%
Devon Energy (DVN)	2014-2019	-54.44%
Permian Resources (PR)	2014-2019	-53.8%
Viatris (VTRS)	2014-2019	-53.67%
Contura Energy (CTRA)	2014-2019	-52.91%
Cameco (CCJ)	2014-2019	-51.86%
GE Aerospace (GE)	2014-2019	-50.89%
Sprouts Farmers Market LLC (SFM)	2014-2019	-49.32%
Alamos Gold (AGI)	2014-2019	-48.96%

Large-cap stocks are treated as having a market cap of $10B+.