InterContinental Hotels Group PLC ADR (IHG) had the highest return between 2001 and 2004 by a US stock, returning 8,020,800%.

ASSET	YEARS	% RETURN
InterContinental Hotels Group PLC ADR (IHG)	2001-2004	8,020,800%
Hirequest (HQI)	2001-2004	4,127,500%
Houston American Energy (HUSA)	2001-2004	253,592.31%
ImmunoPrecise Antibodies (HYFT)	2001-2004	85,614.29%
Xcel Brands (XELB)	2001-2004	28,400%
Oramed Pharmaceuticals (ORMP)	2001-2004	8,275.95%
First Majestic Silver (AG)	2001-2004	7,268.44%
Encore Capital (ECPG)	2001-2004	6,694.29%
Ziff Davis (ZD)	2001-2004	6,032.92%
Axon Enterprise (AXON)	2001-2004	5,326.02%
TherapeuticsMD (TXMD)	2001-2004	4,950.01%
USANA Health Sciences (USNA)	2001-2004	3,809.47%
PetMed Express (PETS)	2001-2004	2,944.17%
Cheniere Energy (LNG)	2001-2004	2,576.47%
MEDIFAST (MED)	2001-2004	2,404.32%
Oragenics (OGEN)	2001-2004	2,267.42%
Urban Outfitters (URBN)	2001-2004	2,229.24%
Versus Systems Inc. (VS)	2001-2004	2,200%
Stratasys (SSYS)	2001-2004	1,901.19%
China Yuchai International (CYD)	2001-2004	1,894.59%
Companhia Siderurgica Nacional ADR (SID)	2001-2004	1,793.69%
FirstCash (FCFS)	2001-2004	1,656.44%
Tractor Supply (TSCO)	2001-2004	1,650.74%
NetEase (NTES)	2001-2004	1,593.33%
Inuvo (INUV)	2001-2004	1,569.57%