QXO (QXO) had the highest return between 2008 and 2012 by a US stock with a market cap of $2B+, returning 1,791,977.8%.

ASSET	YEARS	% RETURN
QXO (QXO)	2008-2012	1,791,977.78%
Aris Mining (ARMN)	2008-2012	22,581.91%
Amneal Pharmaceuticals, Inc Class A Common Stock (AMRX)	2008-2012	719.6%
Regeneron Pharmaceuticals (REGN)	2008-2012	612.2%
Ulta Beauty (ULTA)	2008-2012	484.47%
NewMarket (NEU)	2008-2012	464.34%
Bausch Health Companies (BHC)	2008-2012	459.54%
Cirrus Logic (CRUS)	2008-2012	450.76%
Booking (BKNG)	2008-2012	431.38%
Dorman Products (DORM)	2008-2012	427.68%
Tractor Supply (TSCO)	2008-2012	406.78%
Dillard's (DDS)	2008-2012	401.42%
Expedia (EXPE)	2008-2012	392.43%
ePlus (PLUS)	2008-2012	385.33%
Credit Acceptance (CACC)	2008-2012	384.88%
Steven Madden (SHOO)	2008-2012	376.26%
Dollar Tree (DLTR)	2008-2012	369.44%
Westlake Chemical (WLK)	2008-2012	359.53%
Ross Stores (ROST)	2008-2012	349.07%
Trex (TREX)	2008-2012	330.91%
First Majestic Silver (AG)	2008-2012	319.75%
Polaris Industries (PII)	2008-2012	312.29%
LivaNova (LIVN)	2008-2012	299.16%
XPO Logistics (XPO)	2008-2012	295.03%
Edwards Lifesciences (EW)	2008-2012	294.44%