InterContinental Hotels Group PLC ADR (IHG) had the highest return between 2000 and 2007 by a US stock, returning 11,160,200%.

ASSET	YEARS	% RETURN
InterContinental Hotels Group PLC ADR (IHG)	2000-2007	11,160,200%
QVC (QVCGA)	2000-2007	9,894,038.89%
India Globalization Capital (IGC)	2000-2007	9,833,233.33%
Hirequest (HQI)	2000-2007	9,080,600%
Natwest (NWG)	2000-2007	9,034,940%
Northern Oil & Gas (NOG)	2000-2007	2,278,907.69%
National Grid PLC ADR (NGG)	2000-2007	1,604,552.94%
Houston American Energy (HUSA)	2000-2007	789,452.39%
Know Labs (KNW)	2000-2007	763,220.61%
Perspective Therapeutics (CATX)	2000-2007	669,900%
Gladstone Capital (GLAD)	2000-2007	308,980%
Ring Energy (REI)	2000-2007	263,900%
Ocean Power Technologies (OPTT)	2000-2007	180,233.33%
OPTIMIZERx (OPRX)	2000-2007	149,900%
Gulf Resources (GURE)	2000-2007	55,900%
ImmunoPrecise Antibodies (HYFT)	2000-2007	42,757.14%
First Majestic Silver (AG)	2000-2007	20,294.67%
Gyre Therapeutics (GYRE)	2000-2007	17,414.09%
Broadwind Energy (BWEN)	2000-2007	17,060.69%
Cryoport (CYRX)	2000-2007	15,727.03%
Versus Systems Inc. (VS)	2000-2007	10,020%
Companhia Siderurgica Nacional ADR (SID)	2000-2007	9,962.5%
Dmc Global (BOOM)	2000-2007	9,457.99%
Monster Beverage (MNST)	2000-2007	8,175.34%
RadNet (RDNT)	2000-2007	5,870.59%