Monster Beverage (MNST) had the highest return between 2003 and 2009 by a large-cap US stock, returning 7,189.3%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2003-2009	7,189.29%
Deckers Outdoor (DECK)	2003-2009	2,972.92%
Apple (AAPL)	2003-2009	2,835.97%
ArcelorMittal SA ADR (MT)	2003-2009	2,510.06%
Bancolombia SA ADR (CIB)	2003-2009	2,504.95%
Intuitive Surgical (ISRG)	2003-2009	2,367.03%
Banco Bradesco SA ADR (BBD)	2003-2009	2,348.38%
Booking (BKNG)	2003-2009	2,147.03%
Southern Copper (SCCO)	2003-2009	2,117.06%
Vale SA ADR (VALE)	2003-2009	1,973.47%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2003-2009	1,862.04%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2003-2009	1,764.47%
Illumina (ILMN)	2003-2009	1,699.37%
Itau Unibanco Banco (ITUB)	2003-2009	1,574.98%
Williams Companies (WMB)	2003-2009	1,500.18%
Alamos Gold (AGI)	2003-2009	1,434.57%
Ambev SA ADR (ABEV)	2003-2009	1,434.38%
Akamai Technologies (AKAM)	2003-2009	1,307.78%
Tenaris SA ADR (TS)	2003-2009	1,241.69%
Axon Enterprise (AXON)	2003-2009	1,197.78%
NetEase (NTES)	2003-2009	1,184.96%
Trip Group Ltd ADR (TCOM)	2003-2009	1,118.93%
U-Haul (UHAL)	2003-2009	1,018.46%
Elbit Systems (ESLT)	2003-2009	1,004.19%
America Movil SAB de CV ADR (AMX)	2003-2009	990.77%

Large-cap stocks are treated as having a market cap of $10B+.