Between the 1999-00 and 2008-09 seasons, Kobe Bryant put up the most points per game, with 28.2 per game.

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2000s scoring leaders
Interpreted as:
2000s scoring with a minimum of 41 games played per 82 team games leaders
BryantIversonJamesWadeMcGradyAnthonyCarterNowitzkiPierceO'NealArenasDurantAllenMaloneGarnettDuncanJordanWebberStoudemireJamisonReddRobinsonMashburnBrandRoy28.228.127.525.224.424.223.923.623.323.122.822.722.121.821.621.421.221.121.120.620.520.320.120.019.8
NAMEGPPPGMPGRPGAPGSPGBPGTPGFGMFGAFG%3PM3PA3P%FTMFTAFT%MINPTSREBASTSTLBLKTOVPF+/-
Kobe BryantKobe Bryant74828.239.45.95.21.70.63.19.821.545.71.44.134.27.28.584.429,47621,0654,3813,9211,2464312,3262,092+3470
Allen IversonAllen Iverson68228.141.83.66.22.20.23.69.722.942.41.13.631.17.59.579.328,53319,1542,4714,2271,5211062,4501,198+1187
LeBron JamesLeBron James47227.540.67.06.71.80.93.39.820.947.11.44.132.86.58.873.819,14212,9933,3073,1598304051,541951+1669
Dwyane WadeDwyane Wade39425.237.94.96.71.81.03.88.818.248.30.41.528.57.29.377.214,9259,9221,9252,6257203791,4971,019+1026
Tracy McGradyTracy McGrady67124.437.56.35.21.40.92.58.920.343.51.54.434.05.26.975.025,17716,3804,2303,4899386171,6841,305+1523
Carmelo AnthonyCarmelo Anthony44524.236.26.13.11.10.43.18.718.946.00.72.330.76.17.779.616,11310,7682,7301,3675031991,3751,334+790
Vince CarterVince Carter72723.937.85.44.41.30.72.48.719.544.61.64.337.84.86.179.927,51117,3413,9603,1669145251,7412,211+731
Dirk NowitzkiDirk Nowitzki79223.637.58.92.80.91.02.08.217.347.41.33.538.25.96.787.429,73418,6997,0202,2007478301,5452,073+4665
Paul PiercePaul Pierce76523.337.86.34.01.50.63.17.617.144.31.74.636.36.48.080.128,89317,8124,7983,0681,1834802,3762,201+1925
Shaquille O'NealShaquille O'Neal66223.134.710.62.70.52.22.79.115.558.50.00.00.05.09.552.222,94115,2767,0291,7893441,4311,8182,276+3459
Gilbert ArenasGilbert Arenas43322.837.44.25.51.80.23.37.317.242.72.15.835.86.07.480.916,1759,8531,8282,3877581031,4381,365+96
Kevin DurantKevin Durant15422.736.75.42.61.10.83.08.117.945.31.02.835.95.56.386.75,6533,495830397174128457256-1152
Ray AllenRay Allen72822.137.94.43.81.20.22.37.717.145.22.76.740.34.04.490.027,56116,1013,2382,8019011431,6741,623+2189
Karl MaloneKarl Malone36621.836.08.54.21.40.72.97.816.148.10.00.130.26.27.978.513,1917,9823,1291,5485102431,051994+1303
Kevin GarnettKevin Garnett76921.638.212.14.71.31.62.68.517.149.90.20.728.64.45.679.429,34516,6389,2883,6031,0371,2062,0031,882+3322
Tim DuncanTim Duncan76721.436.511.73.30.82.32.78.216.250.40.00.120.75.17.468.627,97416,4318,9992,5025891,7862,0701,993+5468
Michael JordanMichael Jordan14221.236.15.94.41.50.52.48.720.143.10.20.824.13.74.680.55,1243,01583662120865335290+22
Chris WebberChris Webber50121.136.89.74.31.41.22.78.718.946.10.20.626.73.54.871.418,45010,5694,8362,1467015921,3281,544+1310
Amar'e StoudemireAmar'e Stoudemire43421.134.28.91.40.91.52.67.614.054.10.00.219.25.97.875.514,8489,1393,8815953956391,1121,491+1465
Antawn JamisonAntawn Jamison75120.637.78.11.81.10.41.87.917.345.61.13.134.83.75.074.028,29715,4346,1011,3627992861,3281,845-837
Michael ReddMichael Redd55020.534.04.12.31.00.11.67.216.045.21.84.638.64.35.184.318,70811,2952,2721,25454563907945-303
Glenn RobinsonGlenn Robinson34320.335.46.12.61.20.52.88.017.545.90.92.833.63.33.983.512,1526,9572,087883398182977874-49
Jamal MashburnJamal Mashburn29320.139.16.24.71.00.22.67.618.042.01.33.637.53.64.481.511,4695,8821,8141,38930655768718+726
Elton BrandElton Brand64320.038.010.12.60.92.12.57.715.250.30.00.015.44.76.473.624,42012,8526,5201,6745921,3341,6171,993-1177
Brandon RoyBrandon Roy20919.836.94.65.11.10.21.97.215.646.51.02.836.34.35.480.37,7104,1369681,06023448404413+342