Stephen Curry had the most points by a guard in a game in 2020-21, with 62 points versus the Trail Blazers on January 3, 2021.

Interpreted as:

highest scoring regular-season game by a guard in 2021

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Stephen Curry S. Curry	62	1/3/2021	GSW	vs	POR	36	5	4	0	0	18	31	58.1	8	16	50.0	18	19	94.7	78.8	1	4	5	0	+20
2	Bradley Beal B. Beal	60	1/6/2021	WAS	@	PHI	38	7	5	1	0	20	35	57.1	7	10	70.0	13	15	86.7	72.1	4	3	4	3	-9
3	Stephen Curry S. Curry	57	2/6/2021	GSW	@	DAL	37	2	5	1	0	19	31	61.3	11	19	57.9	8	8	100.0	82.6	0	2	3	3	+7
4	Fred VanVleet F. VanVleet	54	2/2/2021	TOR	@	ORL	37	3	2	3	3	17	23	73.9	11	14	78.6	9	9	100.0	100.1	0	3	1	2	+20
5	Stephen Curry S. Curry	53	4/12/2021	GSW	vs	DEN	36	6	4	0	0	14	24	58.3	10	18	55.6	15	16	93.8	85.4	0	6	5	3	+16
6	Bradley Beal B. Beal	50	5/8/2021	WAS	@	IND	39	5	1	1	2	19	31	61.3	3	7	42.9	9	11	81.8	69.8	4	1	1	1	+8
7	Kevin Porter Jr. K. Porter Jr.	50	4/29/2021	HOU	vs	MIL	41	5	11	0	1	16	26	61.5	9	15	60.0	9	11	81.8	81.1	0	5	5	5	+19
8	Zach LaVine Z. LaVine	50	4/9/2021	CHI	@	ATL	39	8	5	0	0	18	31	58.1	7	12	58.3	7	8	87.5	72.4	1	7	3	1	-3
9	Damian Lillard D. Lillard	50	3/16/2021	POR	vs	NOP	41	6	10	0	0	13	20	65.0	6	13	46.2	18	18	100.0	89.5	1	5	4	3	+9
10	Jamal Murray J. Murray	50	2/19/2021	DEN	@	CLE	38	6	2	2	0	21	25	84.0	8	10	80.0	0	0		100.0	0	6	1	4	+24
11	Stephen Curry S. Curry	49	5/8/2021	GSW	vs	OKC	29	5	2	1	0	14	26	53.8	11	21	52.4	10	10	100.0	80.6	0	5	1	2	+31
12	Stephen Curry S. Curry	49	4/19/2021	GSW	@	PHI	37	3	5	0	0	14	28	50.0	10	17	58.8	11	12	91.7	73.6	0	3	6	2	+11
13	Stephen Curry S. Curry	47	4/17/2021	GSW	@	BOS	37	7	3	0	0	15	27	55.6	11	19	57.9	6	8	75.0	77.0	0	7	5	2	-7
14	Bradley Beal B. Beal	47	1/27/2021	WAS	@	NOP	40	4	6	4	0	17	37	45.9	6	14	42.9	7	7	100.0	58.6	2	2	3	3	-17
15	Stephen Curry S. Curry	46	5/16/2021	GSW	vs	MEM	40	7	9	1	1	16	36	44.4	9	22	40.9	5	6	83.3	59.5	1	6	7	2	+14
16	Bradley Beal B. Beal	46	2/28/2021	WAS	@	BOS	39	7	2	2	1	16	29	55.2	3	6	50.0	11	12	91.7	67.1	2	5	5	1	+2
17	Luka Dončić L. Dončić	46	2/12/2021	DAL	vs	NOP	40	8	12	1	1	17	30	56.7	5	8	62.5	7	9	77.8	67.7	1	7	3	4	+13
18	Zach LaVine Z. LaVine	46	2/10/2021	CHI	vs	NOP	38	7	4	0	1	17	25	68.0	9	14	64.3	3	3	100.0	87.4	1	6	5	0	+20
19	LeBron James L. James	46	1/25/2021	LAL	@	CLE	38	8	6	2	2	19	26	73.1	7	11	63.6	1	2	50.0	85.6	0	8	3	1	+11
20	Kyrie Irving K. Irving	45	5/6/2021	BKN	@	DAL	39	5	4	4	2	17	31	54.8	7	13	53.8	4	4	100.0	68.7	0	5	1	5	-4
21	Bradley Beal B. Beal	45	4/26/2021	WAS	vs	SAS	42	3	1	0	0	20	37	54.1	0	4	0.0	5	5	100.0	57.4	2	1	0	2	-1
22	Devin Booker D. Booker	45	3/31/2021	PHX	vs	CHI	35	4	4	1	1	17	24	70.8	2	5	40.0	9	10	90.0	79.2	1	3	5	3	+7
23	Zach LaVine Z. LaVine	45	1/10/2021	CHI	@	LAC	42	7	7	0	0	15	26	57.7	10	16	62.5	5	5	100.0	79.8	0	7	5	4	-3
24	Gary Trent Jr. G. Trent Jr.	44	4/10/2021	TOR	@	CLE	33	7	4	1	0	17	19	89.5	7	9	77.8	3	3	100.0	108.3	0	7	1	2	+31
25	James Harden J. Harden	44	3/26/2021	BKN	@	DET	42	14	8	1	0	14	30	46.7	4	11	36.4	12	14	85.7	60.8	2	12	3	6	-3