LeBron James has averaged his fewest career points per game against the Pistons, with 24.1 per game.

lebron james lowest career ppg by opponent

OPP	PPG	GP	MPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
Pistons	24.1	63	37.1	6.7	7.1	1.4	0.5	9.0	18.8	47.6	1.3	4.0	31.6	4.9	6.4	77.2	55.7	1.2	5.5	3.0	2,337	1,521	423	448	90	32	191	90	+356
Clippers	25.2	45	38.0	7.9	6.9	1.5	0.8	9.0	19.2	46.8	2.0	5.6	36.5	5.2	7.4	69.9	56.1	1.1	6.8	3.7	1,709	1,136	354	309	67	36	167	96	+83
Rockets	25.4	44	37.1	7.0	6.9	1.3	0.8	9.6	19.9	48.5	1.7	5.2	31.9	4.5	6.6	67.7	55.7	1.1	5.9	3.3	1,633	1,118	308	304	56	33	144	72	-5
Magic	25.5	62	38.2	7.2	7.3	1.6	0.7	9.1	18.7	48.9	1.3	4.3	30.5	5.9	8.0	73.5	57.3	1.0	6.2	3.6	2,367	1,580	445	453	100	44	222	99	+310
Grizzlies	25.6	47	37.0	7.7	7.8	1.9	0.7	9.5	18.4	51.6	1.9	5.1	37.9	4.7	6.3	74.2	60.5	1.1	6.6	3.9	1,741	1,202	360	368	87	32	182	66	+278
Timberwolves	26.0	42	37.5	8.0	7.6	1.5	1.0	9.9	18.7	52.6	1.8	4.5	39.8	4.5	6.2	72.2	60.5	1.1	6.9	3.2	1,574	1,091	338	319	64	44	133	80	+311
Nuggets	26.2	43	37.5	7.4	8.1	1.2	0.7	10.1	20.1	50.0	1.3	4.6	29.1	4.8	6.9	69.3	56.6	1.0	6.4	3.6	1,612	1,128	319	347	50	29	153	80	+20
Knicks	26.5	59	38.2	7.3	7.3	1.8	0.8	9.6	19.5	49.6	1.6	4.8	34.3	5.6	7.7	73.2	58.1	0.9	6.3	3.6	2,251	1,566	428	432	106	46	213	101	+501
Suns	26.6	45	36.5	7.3	7.4	1.7	0.7	9.8	19.1	51.5	1.8	4.9	37.6	5.1	7.0	72.8	60.0	1.0	6.2	3.7	1,640	1,199	327	334	75	32	167	76	+238
Kings	26.7	42	38.0	7.8	8.6	1.7	0.8	9.8	19.4	50.4	1.7	5.3	31.7	5.5	7.1	77.1	59.3	1.3	6.5	3.5	1,597	1,121	329	363	70	35	148	65	+155
Pelicans	27.0	50	38.1	6.7	8.3	1.7	0.6	10.0	19.5	51.4	1.7	4.8	36.6	5.2	6.8	77.5	60.2	1.1	5.6	3.6	1,906	1,351	335	414	83	30	180	84	+258
Raptors	27.0	60	38.3	7.1	7.7	1.2	0.6	9.6	18.6	51.3	1.3	4.0	32.8	6.6	8.7	75.6	60.1	0.9	6.2	3.0	2,297	1,622	427	464	69	33	180	91	+335
Pacers	27.0	66	38.7	7.6	6.7	1.6	0.8	9.8	19.8	49.4	1.3	4.4	30.1	6.2	8.5	73.0	57.5	1.2	6.4	4.0	2,553	1,785	501	442	103	56	261	118	+321
Mavericks	27.2	43	37.6	8.0	7.0	1.4	0.5	9.8	19.8	49.7	1.7	4.7	36.0	5.8	7.5	77.3	58.8	1.3	6.7	3.5	1,617	1,168	342	302	62	22	150	84	+190
76ers	27.2	56	38.2	7.1	7.9	1.6	0.8	10.1	19.6	51.6	1.4	4.3	33.3	5.5	7.5	73.8	59.4	1.1	6.0	3.7	2,140	1,524	399	442	90	46	207	95	+284
Wizards	27.3	58	38.1	7.5	7.4	1.4	0.8	10.1	19.9	50.5	1.6	4.5	35.0	5.6	7.7	72.8	58.6	1.3	6.2	3.7	2,207	1,586	437	431	81	46	217	114	+237
Hawks	27.4	64	38.3	8.0	7.4	1.7	0.8	9.9	19.0	52.0	1.7	4.6	37.8	5.9	8.0	74.1	60.8	1.4	6.6	2.9	2,449	1,752	513	473	108	48	184	115	+482
Lakers	27.6	30	39.3	7.8	7.3	1.7	0.7	10.1	21.1	47.7	1.5	4.6	33.1	6.0	8.8	67.8	55.3	1.5	6.3	3.3	1,180	829	233	218	50	21	99	61	+117
Heat	27.7	45	39.0	6.8	7.0	1.1	0.5	9.8	20.0	48.8	1.6	4.8	33.2	6.6	9.0	73.5	57.8	1.0	5.7	3.6	1,757	1,248	304	314	51	24	160	95	+142
Nets	27.8	61	37.6	7.3	7.6	1.6	0.5	10.1	19.0	52.9	1.3	3.9	34.2	6.3	8.5	74.7	61.1	1.2	6.1	3.9	2,294	1,696	447	463	95	33	235	113	+426
Spurs	27.9	43	37.3	7.5	7.7	1.3	0.5	10.6	21.0	50.2	1.7	4.7	36.8	5.0	7.1	70.0	57.6	1.3	6.2	3.4	1,602	1,198	321	330	55	22	148	87	+34
Warriors	28.0	41	37.4	8.8	7.3	1.2	0.9	10.3	20.4	50.4	2.0	5.2	38.5	5.4	7.6	70.3	58.7	1.5	7.3	3.9	1,532	1,146	362	300	51	36	161	68	+69
Hornets	28.1	56	37.1	7.6	7.6	1.5	0.9	10.4	19.2	54.1	1.5	4.2	36.8	5.8	7.6	76.2	62.4	1.1	6.5	3.4	2,077	1,576	426	425	82	51	188	105	+557
Bulls	28.2	64	38.7	7.6	6.6	1.7	0.8	10.4	20.8	50.2	1.2	4.0	30.8	6.1	8.2	74.5	57.8	1.0	6.6	3.7	2,474	1,803	489	422	108	52	236	120	+297
Thunder	28.2	39	37.9	7.2	7.2	1.7	0.8	10.5	20.4	51.5	2.0	5.1	38.5	5.2	6.8	76.5	60.2	0.9	6.3	3.5	1,478	1,099	282	282	67	32	137	65	+199